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GDF7

  • Official Full Name

    growth differentiation factor 7

  • Overview

    This gene encodes a member of the bone morphogenetic protein (BMP) family. BMPs belong to the transforming growth factor-beta superfamily of secreted signalling molecules that regulate diverse processes in growth, repair and embryonic development. In mouse, this gene functions as an inductive signal from the roof plate required for the specification of neuronal identity in the dorsal spinal cord.
  • Synonyms

    GDF7; growth differentiation factor 7; growth/differentiation factor 7; BMP12; bone morphogenetic protein 12; GDF-7; GDF7_HUMAN; OTTHUMP00000115986;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • E. coli
  • E.coli
  • HEK293
  • Mammalian Cell
  • Wheat Germ
  • C
  • His
  • GST
  • His (Fc)
  • Avi
  • His(C
  • ter)
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human GDF7-28992TH Recombinant Human GDF7 protein E.coli N/A 129
Human GDF7-39H Recombinant Human Growth Differentiation Factor 7 E.coli N/A
Human GDF7-2200H Recombinant Human GDF7 Protein, His-tagged E.coli N-His Thr322-Arg450
Human GDF7-4828H Recombinant Human GDF7 Protein, GST-tagged Wheat Germ GST
Human GDF7-35H Active Recombinant Human GDF7 Protein (Lys352-Arg450), C-His tagged, Animal-free, Carrier-free E.coli C-His Lys352-Arg450
Human GDF7-051H Active Recombinant Human GDF7 Protein E. coli
Human GDF7-107H Recombinant Active Human GDF7 Protein, His-tagged(C-ter) E.coli His(C-ter)
Mouse Gdf7-675M Recombinant Mouse Gdf7 protein E.coli N/A 146
Mouse GDF7-6289M Recombinant Mouse GDF7 Protein Mammalian Cell His
Mouse GDF7-3522M-B Recombinant Mouse GDF7 Protein Pre-coupled Magnetic Beads HEK293
Mouse GDF7-3522M Recombinant Mouse GDF7 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Gdf7-279M Recombinant Mouse Gdf7 Protein, His-tagged E.coli His Ser295~Val447
Rat Gdf7-1573R Recombinant Rat Gdf7 Protein, His-tagged E.coli N-His Arg304-Arg449
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • GDF7 Related Articles
  • GDF7 Related Gene Family

GDF7 involved in several pathways and played different roles in them. We selected most pathways GDF7 participated on our site, such as Hippo signaling pathway, TGF-beta signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with GDF7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Hippo signaling pathwayFzd4;AMH;GSK3B;WWC1;PARD6A;SMAD3;LATS2;PPP2R1B;TGFB2
TGF-beta signaling pathwayINHBAB;TGIF2;ACVR1;AMHR2;BMPR1BB;ZFYVE16;CUL1;BMPR1B;BMPR2A

GDF7 has several biochemical functions, for example, cytokine activity, growth factor activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GDF7 itself. We selected most functions GDF7 had, and list some proteins which have the same functions with GDF7. You can find most of the proteins on our site.

Function Related Protein
cytokine activityCcl27a;GDF5;FAM3B;Fasl;GRN;IL23;BMP5;Ifnz;SPP1
growth factor activityFGF11;HDGF;GDNFA;AMELX;THPO;FGF6A;CSF3;FGF6B;HBEGFB
protein bindingCBX7;TMEM41A;SP3;C8orf48;PARP4;CFI;THBS4;EN1;PDCD4
protein homodimerization activityASNS;PYGL;ADRB3;PFKM;MZF1;GRIK1;RABEP1;MYPOP;BAXA
transforming growth factor beta receptor bindingSMAD2;INHBAB;GDF15;GDF3;BMP8A;BMP7B;BMP8B;GDF7;BMP15

GDF7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GDF7 here. Most of them are supplied by our site. Hope this information will be useful for your research of GDF7.

Bakdash, G; Vogelpoel, LTC; et al. Retinoic acid primes human dendritic cells to induce gut-homing, IL-10-producing regulatory T cells. MUCOSAL IMMUNOLOGY 8:265-278(2015).
Wendroth, SM; Mentrikoski, MJ; et al. GATA3 expression in morphologic subtypes of breast carcinoma: a comparison with gross cystic disease fluid protein 15 and mammaglobin. ANNALS OF DIAGNOSTIC PATHOLOGY 19:6-9(2015).
TGF
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