gdf7
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  • Official Full Name
  • growth differentiation factor 7
  • Background
  • This gene encodes a member of the bone morphogenetic protein (BMP) family. BMPs belong to the transforming growth factor-beta superfamily of secreted signalling molecules that regulate diverse processes in growth, repair and embryonic development. In mouse, this gene functions as an inductive signal from the roof plate required for the specification of neuronal identity in the dorsal spinal cord.
  • Synonyms
  • GDF7; growth differentiation factor 7; growth/differentiation factor 7; BMP12; bone morphogenetic protein 12; GDF-7; GDF7_HUMAN; OTTHUMP00000115986
Cat.#:GDF7-4828HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human GDF7 Protein, GST-tagged
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Cat.#:Gdf7-279MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Gdf7 Protein, His-tagged
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Cat.#:GDF7-28992THTag:N/A
Source (Host):E.coliSpecies:Human
Product nameRecombinant Human GDF7 protein
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Cat.#:GDF7-6289MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse GDF7 Protein
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Cat.#:Gdf7-675MTag:N/A
Source (Host):E.coliSpecies:Mouse
Product nameRecombinant Mouse Gdf7 protein
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Cat.#:GDF7-39HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Growth Differentiation Factor 7
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Involved Pathway

GDF7 involved in several pathways and played different roles in them. We selected most pathways GDF7 participated on our site, such as Hippo signaling pathway, TGF-beta signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with GDF7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Hippo signaling pathway
PARD6A; FZD9; FZD3; Fzd4; WTIP; FZD5; WNT1; YWHAB; ITGB2L; GDF7
TGF-beta signaling pathway
BMP2; BMPR1BA; TNF; INHBE; ID2A; BMPR2; GDF5; GDF6; BMP2B; ACVR2AA

Protein Function

GDF7 has several biochemical functions, for example, cytokine activity, growth factor activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GDF7 itself. We selected most functions GDF7 had, and list some proteins which have the same functions with GDF7. You can find most of the proteins on our site.
Function
Related Protein
Function cytokine activity
Related Protein IL36RN; CER1; CMTM7; GDF6; CCL20A.3; FGF2; FAM3D; CSF1B; TNFSF15; CCL6
Function growth factor activity
Related Protein TGFB1; FGF10B; PDGFA; IL10; FGF13; MSTNB; GMFB; FGF11; TYMP; VEGFB
Function protein binding
Related Protein ZBTB5; ABCG1; UBE2F; NUP107; NDRG1; PDZK1; ECE2; CARM1; HNRNPH2; TTC1
Function protein homodimerization activity
Related Protein DGAT2; GSTM3; ODC1; COQ9; DDX1; GDF6; ABCD2; LMLN; NAMPT; SQSTM1
Function transforming growth factor beta receptor binding
Related Protein NDR1; BMP7B; BMP10; GDF10; BMP5; LRG1; BMP15; INHBC; LFT1; SMAD3

GDF7 Related Articles

Bakdash, G; Vogelpoel, LTC; et al. Retinoic acid primes human dendritic cells to induce gut-homing, IL-10-producing regulatory T cells. MUCOSAL IMMUNOLOGY 8:265-278(2015).
Wendroth, SM; Mentrikoski, MJ; et al. GATA3 expression in morphologic subtypes of breast carcinoma: a comparison with gross cystic disease fluid protein 15 and mammaglobin. ANNALS OF DIAGNOSTIC PATHOLOGY 19:6-9(2015).

GDF7 Related Gene Family

TGF