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Official Full Name growth differentiation factor 7
Background This gene encodes a member of the bone morphogenetic protein (BMP) family. BMPs belong to the transforming growth factor-beta superfamily of secreted signalling molecules that regulate diverse processes in growth, repair and embryonic development. In mouse, this gene functions as an inductive signal from the roof plate required for the specification of neuronal identity in the dorsal spinal cord.
Synonyms GDF7; growth differentiation factor 7; growth/differentiation factor 7; BMP12; bone morphogenetic protein 12; GDF-7; GDF7_HUMAN; OTTHUMP00000115986
    • Species :
    • Human
    • Mouse
    • Source :
    • E.coli
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human GDF7-28992TH Recombinant Human GDF7 protein E.coli N/A
    Human GDF7-39H Recombinant Human Growth Differentiation Factor 7 E.coli N/A
    Human GDF7-4828H Recombinant Human GDF7 Protein, GST-tagged Wheat Germ GST
    Mouse Gdf7-279M Recombinant Mouse Gdf7 Protein, His-tagged E.coli His
    Mouse GDF7-6289M Recombinant Mouse GDF7 Protein Mammalian Cell His
    Mouse Gdf7-675M Recombinant Mouse Gdf7 protein E.coli N/A

    GDF7 involved in several pathways and played different roles in them. We selected most pathways GDF7 participated on our site, such as Hippo signaling pathway, TGF-beta signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with GDF7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Hippo signaling pathway CCND2; PARD3; WNT4; FZD2; FGF1; GDF6; FZD8; AREG; BIRC5; TGFBR2
    TGF-beta signaling pathway SKP1; RPS6KB1; BMPR1A; ID2A; GDF5; RBX1; TGFBR1A; BAMBI; SMAD1; PPP2R1B

    GDF7 has several biochemical functions, for example, cytokine activity, growth factor activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GDF7 itself. We selected most functions GDF7 had, and list some proteins which have the same functions with GDF7. You can find most of the proteins on our site.

    Function Related Protein
    cytokine activity FAM3C; TGFB2; LTA; IFNA12; TIMP1; TNFSF13B; IFNPHI2; IL36B; IFNA3; FASLG
    growth factor activity VHL; CECR1; AMH; FGF10B; GDF15; FIGF; VEGFAA; CLCF1; VEGFB; TYMP
    protein binding UQCRC2; NLK; LPL; CD2BP2; APOBEC3H; Trf; PLXDC1; C7orf49; SMG5; PHC2
    protein homodimerization activity CSF1; CCDC88A; KCNE2; ADD2; STK25; TENM1; ENO2; PDXK; BNIP3; Pdgfa&Pdgfb
    transforming growth factor beta receptor binding SMAD3; BMP5; TGFB2; NDR1; MSTN; GDF15; MSTNB; GDF6; GDF1; FKBP1A

    GDF7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GDF7 here. Most of them are supplied by our site. Hope this information will be useful for your research of GDF7.

    Bakdash, G; Vogelpoel, LTC; et al. Retinoic acid primes human dendritic cells to induce gut-homing, IL-10-producing regulatory T cells. MUCOSAL IMMUNOLOGY 8:265-278(2015).
    Wendroth, SM; Mentrikoski, MJ; et al. GATA3 expression in morphologic subtypes of breast carcinoma: a comparison with gross cystic disease fluid protein 15 and mammaglobin. ANNALS OF DIAGNOSTIC PATHOLOGY 19:6-9(2015).


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