Recombinant Mouse Gdf7 protein

Name: Recombinant Mouse Gdf7 protein
SKU: Gdf7-675M

Specification
Gene Information
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Species :	Mouse
Source :	E.coli
Tag :	Non
Protein Length :	146
Description :	Growth/differentiation factors (GDF-1 to GDF-15) are members of the BMP family of TGF-beta superfamily proteins. They are produced as inactive preproproteins which are then cleaved and assembled into active secreted homodimers. GDF dimers are disulfide-linked with the exception of GDF-3 and -9. GDF proteins are important during embryonic development, particularly in the skeletal, nervous, and muscular systems.
Form :	Lyophilized from a 0.2μm filtered concentrated solution in 30 % Acetonitrile and 0.1 % TFA.
Bio-activity :	Fully biologically active when compared to standard. The ED50 as determined by inducing alkaline phosphatase production of murine ATDC5 cells is less than 0.5 μg/ml, corresponding to a specific activity of > 2000 IU/mg.
Molecular Mass :	Approximately 29.8 kDa, a homodimeric protein consisting of two 146 amino acid non-glycosylated polypeptide chains.
AA Sequence :	TALAGTRGAQGSGGGGGGGGGGGGGGGGGGGGAGRGHGRRGRSRCSRKSLHVDFKELGWDDWIIAPLDYEAYHCEGVCDFPLRSHLEPTNHAIIQTLLNSMAPDAAPASCCVPARLSPISILYIDAANNVVYKQYEDMVVEACGCR
Endotoxin :	Less than 0.1 EU/µg of rMuGDF-7/BMP-12 as determined by LAL method.
Purity :	>95% by SDS-PAGE and HPLC analysis.
Storage :	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 centigrade as supplied. 1 month, 2 to 8 centigrade under sterile conditions after reconstitution. 3 months, -20 to -70 centigrade under sterile conditions after reconstitution.
Reconstitution :	We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤-20 centigrade. Further dilutions should be made in appropriate buffered solutions.

Gene Name	Gdf7
Official Symbol	Gdf7
Synonyms	GDF7; growth differentiation factor 7; growth/differentiation factor 7; GDF-7; BMP12;
Gene ID	238057
mRNA Refseq	NM_013527
Protein Refseq	NP_038555
UniProt ID	P43029