Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at BIO-Europe Spring|March 18–20, 2024|Booth #34

Hmox1

  • Official Full Name

    heme oxygenase (decycling) 1

  • Overview

    Heme oxygenase, an essential enzyme in heme catabolism, cleaves heme to form biliverdin, which is subsequently converted to bilirubin by biliverdin reductase, and carbon monoxide, a putative neurotransmitter. Heme oxygenase activity is induced by its substrate heme and by various nonheme substances. Heme oxygenase occurs as 2 isozymes, an inducible heme oxygenase-1 and a constitutive heme oxygenase-2. HMOX1 and HMOX2 belong to the heme oxygenase family.
  • Synonyms

    32 kD; bK286B10; D8Wsu38e; heat shock protein 32 kD; heat shock protein 32kD; Heat shock protein; Heme oxygenase (decycling) 1; Heme oxygenase 1; Hemox; HMOX 1; Hmox; HMOX1; HMOX1_HUMAN; HO 1; HO; HO-1; HO1; Hsp32;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Cattle
  • Chicken
  • Human
  • Mouse
  • Pig
  • Rat
  • E. coli
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • Yeast
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • His|GST
  • His|MBP
  • His|S
  • His|T7
  • B2M
  • Myc
  • DDK
  • MYC
  • N/A
  • N
  • Tag Free
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human HMOX1-138H Active Recombinant Human HMOX1 protein, His-tagged E.coli His
Human HMOX1-2604H Recombinant Human HMOX1 protein, His & S-tagged E.coli His/S Leu61~Ile172 (Accession # P09601)
Human HMOX1-27002TH Recombinant Human HMOX1 E.coli N/A 288 amino acids
Human HMOX1-137H Recombinant Human Heme Oxygenase 1, His-tagged E.coli His
Human HMOX1-277H Recombinant Human HMOX1 protein, His/MBP-tagged E.coli His/MBP 175-266 aa
Human HMOX1-4884H Recombinant Human HMOX1 Protein, GST-tagged Wheat Germ GST
Human HMOX1-1556H Recombinant Human HMOX1 protein, His-tagged E.coli His
Human HMOX1-1597H Recombinant Human Heme Oxygenase (decycling) 1, GST-tagged E.coli GST
Human HMOX1-27877TH Recombinant Human HMOX1, His-tagged E.coli His
Human HMOX1-5467HCL Recombinant Human HMOX1 293 Cell Lysate HEK293 N/A
Human HMOX1-023H Recombinant Human HMOX1 Protein, His-tagged E.coli His 1-265
Human HMOX1-061H Recombinant Human HMOX1 Protein, His-tagged E. coli His 1-265
Human HMOX1-5723H Recombinant Human HMOX1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human HMOX1-3040H Recombinant Human HMOX1 protein, His-tagged E.coli His 3-288aa
Human HMOX1-3665HF Recombinant Full Length Human HMOX1 Protein, GST-tagged In Vitro Cell Free System GST 288 amino acids
Human HMOX1-2248H Recombinant Human HMOX1 Protein, His-tagged E.coli N-His Met1-Met288
Human HMOX1-1170HFL Recombinant Full Length Human HMOX1 Protein, C-Flag-tagged Mammalian cells Flag
Human HMOX1-1083H-B Recombinant Human HMOX1 Protein Pre-coupled Magnetic Beads HEK293
Human HMOX1-1083H Recombinant Human HMOX1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human HMOX1-3082H Recombinant Human HMOX1 Protein (Met1-Thr261) E.coli Tag Free Met1-Thr261
Human HMOX1-3083H Recombinant Human HMOX1 Protein (Leu61-Ile172), N-His tagged E.coli N-His Leu61-Ile172
Mouse Hmox1-2605M Recombinant Mouse Hmox1 protein, His & S-tagged E.coli His/S Pro99~Arg237 (Accession # P14901)
Mouse HMOX1-7743M Recombinant Mouse HMOX1 Protein Mammalian Cell His
Mouse HMOX1-1412M Recombinant Mouse HMOX1 Protein (1-289 aa), His-tagged Yeast His 1-289 aa
Mouse Hmox1-3041M Recombinant Mouse Hmox1 protein, His-B2M-tagged E.coli His-B2M 1-289aa
Mouse HMOX1-4248M Recombinant Mouse HMOX1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Hmox1-1141M Recombinant Mouse Hmox1 Protein, MYC/DDK-tagged HEK293T MYC/DDK
Mouse HMOX1-4248M-B Recombinant Mouse HMOX1 Protein Pre-coupled Magnetic Beads HEK293
Rat HMOX1-2872R Recombinant Rat HMOX1 Protein Mammalian Cell His
Rat Hmox1-31R Recombinant Rat Hmox1, His-tagged E.coli His
Rat Hmox1-1557R Recombinant Rat Hmox1 protein, His-tagged E.coli His
Rat Hmox1-32R Recombinant Rat Hmox1 protein, His-tagged E.coli His Gln145~Arg237
Rat Hmox1-716R Recombinant Rat Heme Oxygenase (Decycling) 1 E.coli N/A
Rat Hmox1-2758R Recombinant Rat Hmox1 Protein, His-tagged E.coli N-His Met1-Met289
Rat HMOX1-2527R-B Recombinant Rat HMOX1 Protein Pre-coupled Magnetic Beads HEK293
Rat HMOX1-2527R Recombinant Rat HMOX1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat HMOX1-2493R Recombinant Rat HMOX1 Protein (1-289 aa), His-tagged Yeast His 1-289 aa
Cattle HMOX1-2603C Recombinant Cattle HMOX1 protein, His & T7-tagged E.coli His/T7 Met1~Met289
Pig HMOX1-2606P Recombinant Pig HMOX1 protein, His & S-tagged E.coli His/S Leu61~Val172 (Accession # P32394)
Pig HMOX1-2607P Recombinant Pig HMOX1 protein, His & GST-tagged E.coli His/GST Met1~Met288 (Accession # P32394)
Chicken HMOX1-6896C Recombinant Chicken HMOX1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Hmox1 Related Articles
  • Hmox1 Related Research Area

Hmox1 involved in several pathways and played different roles in them. We selected most pathways Hmox1 participated on our site, such as Porphyrin and chlorophyll metabolism, HIF- signaling pathway, Mineral absorption, which may be useful for your reference. Also, other proteins which involved in the same pathway with Hmox1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Porphyrin and chlorophyll metabolismHCCSA.1;HMBSB;UGT2A1;ALAS1;HMOX2;UGT5G1;CPOX;EARS2;UGT2A2
HIF- signaling pathwayIFNGR2;PIK3CG;IGF1;IL6;MKNK2;ENO3;GAPDH;ANGPT2;PIK3R2
Mineral absorptionMT1X;STEAP1;SLC8A1;SLC30A1;SLC26A9;MT2A;SLC11A2;HEPH;ATP1B3
MicroRNAs in cancerTGFB2;ITGA5;IRS1;PDGFA;THBS1;PRKCA;TRP53;IGF2BP1;BCL2L2

Hmox1 has several biochemical functions, for example, enzyme binding, heme binding, heme oxygenase (decyclizing) activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Hmox1 itself. We selected most functions Hmox1 had, and list some proteins which have the same functions with Hmox1. You can find most of the proteins on our site.

Function Related Protein
enzyme bindingPRKCE;HIST1H2AG;PPP1R3D;PTPLAD1;HIST1H2AM;PIAS3;CUTA;HYAL2;HAND2
heme bindingCYB5B;NOS2;CBSB;CYP19A1B;HBAA1;CYP21A2;CYP2AA3;CYP2J6;CYP8B1
heme oxygenase (decyclizing) activityHMOX2A;HMOX1B;HMOX1;HMOX1A;HMOX2
metal ion bindingSNAI2;TET3;CYBA;OSGEPL1;ZNF133;KDM7AB;ATP2C2;ZNF295;DGKAA
phospholipase D activityPLD3;PLD2;GPLD1;PLD1A;PLD4;HMOX1;PLD1
protein bindingRPL5;CTBP1;COA6;RNF180;BID;TFF3;YY1AP1;PARN;FRMD7
protein homodimerization activitySNX1;NR4A2;SUPV3L1;CECR1;CRYBA1;ALDH1A3;CLIC6;GAMT;IKBKB
signal transducer activityGPR27;TAS2R140;GRM8B;PTH1RB;GPR34A;GNGT2B;OPN1MW3;VAPA;MRGPRG

Hmox1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Hmox1 here. Most of them are supplied by our site. Hope this information will be useful for your research of Hmox1.

POT1; CREB3; ASL; TERF1; proS; q7ckk6_yerpe; hemL2; comEA; yvaE; gcvP

Muhsain, SNF; Lang, MA; et al. Mitochondrial targeting of bilirubin regulatory enzymes: An adaptive response to oxidative stress. TOXICOLOGY AND APPLIED PHARMACOLOGY 282:77-89(2015).
Repesse, Y; Peyron, I; et al. Development of inhibitory antibodies to therapeutic factor VIII in severe hemophilia A is associated with microsatellite polymorphisms in the HMOX1 promoter. HAEMATOLOGICA 98:1650-1655(2013).
  • Q&As
  • Reviews

Q&As (5)

Ask a question
Can you discuss the role of HMOX1 in modulating the immune response in the context of infectious diseases, and how its induction may impact host-pathogen interactions? 03/02/2022

HMOX1 modulates the immune response during infectious diseases, influencing host-pathogen interactions. Its induction can contribute to an anti-inflammatory environment and impact the outcome of infections.

How does HMOX1 contribute to the regulation of iron homeostasis, and what are the molecular mechanisms involved in its interaction with iron-responsive elements? 06/10/2020

HMOX1 regulates iron homeostasis by releasing free iron during heme degradation. Its interaction with iron-responsive elements influences cellular iron levels and responses to iron availability.

What is the relationship between HMOX1 and oxidative stress-induced autophagy, and how does this connection influence cellular responses to stressors? 01/23/2019

HMOX1 is linked to oxidative stress-induced autophagy, contributing to cellular adaptation and survival. This connection influences the cellular response to stressors by promoting self-cleaning mechanisms.

Can you discuss the role of HMOX1 in vascular health and its impact on endothelial function, particularly in the context of cardiovascular diseases? 12/18/2018

HMOX1 plays a role in vascular health by protecting endothelial cells. Its anti-inflammatory and vasodilatory effects contribute to cardiovascular protection and may have implications for disease prevention.

How does HMOX1 participate in the modulation of the immune response, and what are the mechanisms by which it influences inflammatory pathways? 10/14/2018

HMOX1 modulates the immune response by suppressing inflammation. It inhibits pro-inflammatory pathways by influencing transcription factors and inhibiting the production of inflammatory mediators.

Customer Reviews (3)

Write a review
Reviews
10/03/2021

    A reliable source for top-notch proteins. Fast shipping is a big plus.

    04/14/2020

      Exceptional service! This product has become a staple in our lab.

      09/30/2018

        Impressed with the product's quality. Shipping is always on time.

        Ask a Question for All Hmox1 Products

        Required fields are marked with *

        My Review for All Hmox1 Products

        Required fields are marked with *

        logo

        FOLLOW US

        Terms and Conditions        Privacy Policy

        Copyright © 2024 Creative BioMart. All Rights Reserved.

        Contact Us

        • /

        Stay Updated on the Latest Bioscience Trends