hmox1
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  • Official Full Name
  • heme oxygenase (decycling) 1
  • Background
  • Heme oxygenase, an essential enzyme in heme catabolism, cleaves heme to form biliverdin, which is subsequently converted to bilirubin by biliverdin reductase, and carbon monoxide, a putative neurotransmitter. Heme oxygenase activity is induced by its substrate heme and by various nonheme substances. Heme oxygenase occurs as 2 isozymes, an inducible heme oxygenase-1 and a constitutive heme oxygenase-2. HMOX1 and HMOX2 belong to the heme oxygenase family.
  • Synonyms
  • 32 kD; bK286B10; D8Wsu38e; heat shock protein 32 kD; heat shock protein 32kD; Heat shock protein; Heme oxygenase (decycling) 1; Heme oxygenase 1; Hemox; HMOX 1; Hmox; HMOX1; HMOX1_HUMAN; HO 1; HO; HO-1; HO1; Hsp32
Cat.#:HMOX1-1412MTag:His
Source (Host):YeastSpecies:Mouse
Product nameRecombinant Mouse HMOX1 Protein (1-289 aa), His-tagged
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Cat.#:HMOX1-2493RTag:His
Source (Host):YeastSpecies:Rat
Product nameRecombinant Rat HMOX1 Protein (1-289 aa), His-tagged
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Cat.#:HMOX1-4884HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human HMOX1 Protein, GST-tagged
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Cat.#:HMOX1-1597HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Heme Oxygenase (decycling) 1, GST-tagged
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Cat.#:HMOX1-137HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Heme Oxygenase 1, His-tagged
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Cat.#:HMOX1-138HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human HMOX1 protein, His-tagged
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Cat.#:HMOX1-1556HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinent Human HMOX1 protein, His-tagged
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Cat.#:HMOX1-2604HTag:His/S
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human HMOX1 protein, His & S-tagged
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Cat.#:HMOX1-27002THTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human HMOX1
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Cat.#:HMOX1-277HTag:His/MBP
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human HMOX1 protein, His/MBP-tagged
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Cat.#:HMOX1-27877THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human HMOX1, His-tagged
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Cat.#:Hmox1-2605MTag:His/S
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Hmox1 protein, His & S-tagged
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Cat.#:HMOX1-7743MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse HMOX1 Protein
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Cat.#:Hmox1-1557RTag:His
Source (Host):E. coliSpecies:Rat
Product nameRecombinent Rat Hmox1 protein, His-tagged
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Cat.#:HMOX1-2872RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat HMOX1 Protein
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Cat.#:Hmox1-31RTag:His
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Hmox1, His-tagged
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Cat.#:Hmox1-32RTag:His
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Hmox1 protein, His-tagged
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Cat.#:Hmox1-716RTag:N/A
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Heme Oxygenase (Decycling) 1
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Cat.#:HMOX1-6896CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken HMOX1
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Cat.#:HMOX1-2603CTag:His/T7
Source (Host):E. coliSpecies:Cattle
Product nameRecombinant Cattle HMOX1 protein, His & T7-tagged
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Cat.#:HMOX1-2606PTag:His/S
Source (Host):E. coliSpecies:Pig
Product nameRecombinant Pig HMOX1 protein, His & S-tagged
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Cat.#:HMOX1-2607PTag:His/GST
Source (Host):E. coliSpecies:Pig
Product nameRecombinant Pig HMOX1 protein, His & GST-tagged
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Cat.#:HMOX1-5467HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human HMOX1 293 Cell Lysate
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Involved Pathway

Hmox1 involved in several pathways and played different roles in them. We selected most pathways Hmox1 participated on our site, such as Porphyrin and chlorophyll metabolism, HIF- signaling pathway, Mineral absorption, which may be useful for your reference. Also, other proteins which involved in the same pathway with Hmox1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Porphyrin and chlorophyll metabolism
UGT1A2; UGT2A2; UGT1AB; UGT2B15; UGT1A3; UGT1A9; UROD; HEPH; CPOX; ALAS2
HIF- signaling pathway
AKT2; GM5506; VEGFA; EP300; GAPDH; Trf; HK1; INS; IFNGR1; TEK
Mineral absorption
SLC11A2; STEAP2; S100G; HMOX1; FTL; SLC26A6; CLCN2; ATP1A1; SLC5A1; ATP1B3
MicroRNAs in cancer
PIK3R2; PDGFA; ERBB3; MMP9; WNT3; SERPINB5; APC2; GRB2; ST14; CDC25A

Protein Function

Hmox1 has several biochemical functions, for example, enzyme binding, heme binding, heme oxygenase (decyclizing) activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Hmox1 itself. We selected most functions Hmox1 had, and list some proteins which have the same functions with Hmox1. You can find most of the proteins on our site.
Function
Related Protein
Function enzyme binding
Related Protein RAD9A; DHCR24; CD4; PRTN3; ZFP346; CLSTN2; HDAC6; PDE4DIP; CYB5A; HLCS
Function heme binding
Related Protein NOX5; TDO2A; DUOX2; CYP4F3; NR1D1; CYP1A; CYP1C1; CYP4F2; CYP3A7; CYP2P10
Function heme oxygenase (decyclizing) activity
Related Protein HMOX2A; HMOX1; HMOX1B; HMOX2; HMOX1A
Function metal ion binding
Related Protein ZNF497; GALNS; JUB; ZNF134; ZNF821; YY1B; SMAD5; FOXP1; NME2; ZBTB12.2
Function phospholipase D activity
Related Protein PLD1A; GPLD1; PLD1; PLD3; PLD4; PLD2; HMOX1
Function protein binding
Related Protein HYI; NIPSNAP3A; COPS7B; ING2; AP2B1; RALBP1; SCARB1; ARID1A; ABCE1; SCYL3
Function protein homodimerization activity
Related Protein CBLN1; FLT3; TFAP2A; MLL1; CER1; MTUS2; FASN; SNX6; ERP29; GCA
Function signal transducer activity
Related Protein OLFR181; OLFR1002; GPR158; GNAQ; TMTOPS2B; DRD1B; CSPG4; OLFR78; GPR31B; GNG12

Interacting Protein

Hmox1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Hmox1 here. Most of them are supplied by our site. Hope this information will be useful for your research of Hmox1.
POT1; CREB3; ASL; TERF1; proS; q7ckk6_yerpe; hemL2; comEA; yvaE; gcvP

Hmox1 Related Articles

Muhsain, SNF; Lang, MA; et al. Mitochondrial targeting of bilirubin regulatory enzymes: An adaptive response to oxidative stress. TOXICOLOGY AND APPLIED PHARMACOLOGY 282:77-89(2015).
Repesse, Y; Peyron, I; et al. Development of inhibitory antibodies to therapeutic factor VIII in severe hemophilia A is associated with microsatellite polymorphisms in the HMOX1 promoter. HAEMATOLOGICA 98:1650-1655(2013).