|Official Full Name||insulin-like growth factor binding protein 4|
|Background||This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein binds both insulin-like growth factors (IGFs) I and II and circulates in the plasma in both glycosylated and non-glycosylated forms. Binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors.|
|Synonyms||IGFBP4; insulin-like growth factor binding protein 4; BP-4; IBP4; IGFBP-4; HT29-IGFBP; insulin-like growth factor-binding protein 4; IBP-4; IGF-binding protein 4; Insulin-like growth factor-binding protein 4|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
IGFBP4 involved in several pathways and played different roles in them. We selected most pathways IGFBP4 participated on our site, such as Metabolism of proteins, Myometrial Relaxation and Contraction Pathways, Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs), which may be useful for your reference. Also, other proteins which involved in the same pathway with IGFBP4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Metabolism of proteins||IGFALS; ARSF; ZNF408; LTF; DDOST; HSCB; F9B; FXC1; CNIH; MLEC|
|Myometrial Relaxation and Contraction Pathways||ACTA1; GABPA; RGS18; GUCA2A; RGS17; RGS6; IGFBP6; CNN1; ATF5; CRH|
|Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)||IGFBP5; IGFBP5A; KLK13; IGFALS; IGFBP6; IGFBP4; IGFBP1A; IGF2B; IGFBP6A; IGFBP2A|
|Wnt signaling network||RYK; ATP6AP2; RSPO1; IGFBP4; WIF1; CTHRC1|
IGFBP4 has several biochemical functions, for example, insulin-like growth factor I binding, insulin-like growth factor II binding. Some of the functions are cooperated with other proteins, some of the functions could acted by IGFBP4 itself. We selected most functions IGFBP4 had, and list some proteins which have the same functions with IGFBP4. You can find most of the proteins on our site.
|insulin-like growth factor I binding||IGF1R; IGFBP5; IGFBP5A; INSR; IGFBP2A; IGFBP4; IGFBP6A; IGFBP6; IGFBP6B; IGFBP3|
|insulin-like growth factor II binding||IGFBP6; IGFBP5; IGFBP5A; IGFBP6B; IGFBP2; IGFBP3; IGFBP5B; IGFBP2A; IGFBP4; IGFBP2B|
IGFBP4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IGFBP4 here. Most of them are supplied by our site. Hope this information will be useful for your research of IGFBP4.
SUV39H1; KDM1A; q81l39_bacan