il37
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  • Official Full Name
  • interleukin 37
  • Background
  • The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine can bind to, and may be a ligand for interleukin 18 receptor (IL18R1/IL-1Rrp). This cytokine also binds to interleukin 18 binding protein (IL18BP), an inhibitory binding protein of interleukin 18 (IL18), and subsequently forms a complex with IL18 receptor beta subunit, and through which it inhibits the activity of IL18. This gene along with eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Five alternatively spliced transcript variants encoding distinct isoforms have been reported.
  • Synonyms
  • interleukin 1 family, member 7 (zeta); Interleukin-1-related protein; FIL1Z; FIL1 zeta; IL-1 zeta; IL-1H4; IL-1RP1; IL-1X protein; IL1H4; IL1RP1; interleukin 1 family member 7; FIL1; interleukin 1, zeta; FIL1(ZETA); interleukin-1 family member 7; Interleukin-1 homolog 4; interleukin-1 superfamily z; Interleukin-1 zeta; IL-1X; IL-37; IL1F7; IL-1F7; interleukin-23; OTTHUMP00000162032; OTTHUMP00000162033; OTTHUMP00000162034; OTTHUMP00000162035; OTTHUMP00000162036; IL-1F7b (IL-1H4, IL-1H, IL-1RP1); IL1F7 (canonical product IL-1F7b); interleukin 37; IL37; IL-1H
Cat.#:IL1F7-318HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human IL1F7
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Cat.#:IL1F7-14171HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human IL1F7, GST-tagged
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Cat.#:IL37-142HTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human IL37 protein
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Cat.#:IL37-370HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human IL37, His-tagged
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Cat.#:IL37-753HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human IL37 protein
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Cat.#:IL37-7843HTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human IL37
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Cat.#:IL37-853HTag:Met
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human IL37
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Cat.#:IL1F7-159HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Interleukin 1 Family, Member 7, His-tagged
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Cat.#:IL37-5237HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human IL1F7 293 Cell Lysate
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Protein Function

IL37 has several biochemical functions, for example, cytokine activity, interleukin-1 receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by IL37 itself. We selected most functions IL37 had, and list some proteins which have the same functions with IL37. You can find most of the proteins on our site.
Function
Related Protein
Function cytokine activity
Related Protein INHBAB; CLCF1; FLT3LG; IL36RN; HMGB1; FGF2; LEFTY1; Ctf2; SP100; OSTN
Function interleukin-1 receptor binding
Related Protein IL36B; IL1F10; IRAK4; TLR5; IL1A; IL36A; IL37; TLR9; IRAK1; IL36RN

Interacting Protein

IL37 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IL37 here. Most of them are supplied by our site. Hope this information will be useful for your research of IL37.
SMAD3

IL37 Related Articles

Hu, ZL; Chen, ZY; et al. Expression, purification of IL-38 in Escherichia coli and production of polyclonal antibodies. PROTEIN EXPRESSION AND PURIFICATION 107:76-82(2015).
Lee, KW; Kim, DK; et al. Immune modulation by Bacillus subtilis-based direct-fed microbials in commercial broiler chickens. ANIMAL FEED SCIENCE AND TECHNOLOGY 200:76-85(2015).