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Active Recombinant Human IL37 Protein (Lys53-Asp218), C-His tagged, Animal-free, Carrier-free

Cat.No. : IL37-124H
Product Overview : Recombinant Human IL37 Protein (Lys53-Asp218) with C-His tag was expressed in E. coli and Animal-free as well as Carrier-free.
  • Specification
  • Gene Information
  • Related Products
Description : Interleukin-37 (IL-37) consists of 192 amino acids. IL-37 is a member of the interleukin-1 cytokine family. The primary function is binding to the interleukin-18 receptor (IL18R1 /IL-1Rrp) and then becoming a subunit to inhibit the activity of IL-18. This behavior often occurs between various immune responses. It also significantly affects the negative regulation of tumor necrosis factor production.
Source : E. coli
Species : Human
Tag : C-His
Form : Lyophilized
Bio-activity : Measure by its ability to induce IL-8 secretion in human PBMCs. The ED50 for this effect is < 0.9 μg/mL.
Molecular Mass : The protein has a calculated MW of 19.49 kDa.
The protein migrates as 22 kDa under reducing condition (SDS-PAGE analysis).
Protein Length : Lys53-Asp218
Endotoxin : < 0.1 EU/μg of the protein by the LAL method.
Purity : >95% as determined by SDS-PAGE analysis.
Storage : This product is stable after storage at:
-20 centigrade for 12 months in lyophilized state from date of receipt.
-20 or -80 centigrade for 1 month under sterile conditions after reconstitution.
Avoid repeated freeze/thaw cycles.
Storage Buffer : Lyophilized from a 0.2 μm filtered solution of PBS, pH 8.0.
Reconstitution : It is recommended to reconstitute the lyophilized protein in sterile H2O to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.
Shipping : The product is shipped with polar packs. Upon receipt, store it immediately at -20 centigrade or lower for long term storage.
Gene Name : IL37 interleukin 37 [ Homo sapiens (human) ]
Official Symbol : IL37
Synonyms : IL37; interleukin 37; IL1F7, interleukin 1 family, member 7 (zeta); interleukin-37; FIL1; FIL1(ZETA); FIL1Z; IL 1F7; IL 1H4; IL 1RP1; interleukin 1; zeta; interleukin 1 homolog 4; interleukin 1 related protein; FIL1 zeta; IL-1 zeta; IL-1X protein; interleukin-23; interleukin 1, zeta; interleukin-1 homolog 4; interleukin-1 superfamily z; interleukin 1 family member 7; interleukin-1-related protein; IL-1F7b (IL-1H4, IL-1H, IL-1RP1); IL1F7 (canonical product IL-1F7b); IL-1H; IL-37; IL1F7; IL1H4; IL-1F7; IL-1H4; IL1RP1; IL-1RP1;
Gene ID : 27178
mRNA Refseq : NM_014439
Protein Refseq : NP_055254
MIM : 605510
UniProt ID : Q9NZH6

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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