IRF8 has several biochemical functions, for example, protein binding, regulatory region DNA binding, transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding. Some of the functions are cooperated with other proteins, some of the functions could acted by IRF8 itself. We selected most functions IRF8 had, and list some proteins which have the same functions with IRF8. You can find most of the proteins on our site.
Function protein binding
Related Protein KRT18; MUTED; NFE2; SEMA7A; PARP2; DNTT; SIK3; NTSR1; ARPC2; BPTF
Function regulatory region DNA binding
Related Protein IRF1B; NFKB1; IRF5; IRF4A; IRF6; IRF1A; IRF8; IRF2A; HMGA2; IRF3
Function transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
Related Protein POU3F1; PAX3; PROX1; IRF8; FOXC1; JUN; FOXP3; SOX17; PTH; FOXC2