Recombinant Human IRF8 Protein, GST-tagged

• Cat.No.: IRF8-5033H
• Product Overview: Human IRF8 full-length ORF ( NP_002154.1, 1 a.a. - 426 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: Interferon consensus sequence-binding protein (ICSBP) is a transcription factor of the interferon (IFN) regulatory factor (IRF) family. Proteins of this family are composed of a conserved DNA-binding domain in the N-terminal region and a divergent C-terminal region that serves as the regulatory domain. The IRF family proteins bind to the IFN-stimulated response element (ISRE) and regulate expression of genes stimulated by type I IFNs, namely IFN-alpha and IFN-beta. IRF family proteins also control expression of IFN-alpha and IFN-beta-regulated genes that are induced by viral infection. [provided by RefSeq
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 74.8 kDa
• AA Sequence: MCDRNGGRRLRQWLIEQIDSSMYPG LIWENEEKSMFRIPWKHAGKQDYNQ EVDASIFKAWAVFKGKFKEGDKAEP ATWKTRLRCALNKSPDFEEVTDRSQ LDISEPYKVYRIVPEEEQKCKLGVA TAGCVNEVTEMECGRSEIDELIKEP SVDDYMGMIKRSPSPPEACRSQLLP DWWAQQPSTGVPLVTGYTTYDAHHS AFSQMVISFYYGGKLVGQATTTCPE GCRLSLSQPGLPGTKLYGPEGLELV RFPPADAIPSERQRQVTRKLFGHLE RGVLLHSSRQGVFVKRLCQGRVFCS GNAVVCKGRPNKLERDEVVQVFDTS QFFRELQQFYNSQGRLPDGRVVLCF GEEFPDMAPLRSKLILVQIEQLYVR QLAEEAGKSCGAGSVMQAPEEPPPD QVFRMFPDICASHQRSFFRENQQIT V
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: IRF8 interferon regulatory factor 8 [ Homo sapiens ]
• Official Symbol: IRF8
• Synonyms: IRF8; interferon regulatory factor 8; ICSBP1, interferon consensus sequence binding protein 1; ICSBP; IRF 8; interferon consensus sequence binding protein 1; IRF-8; ICSBP1; H-ICSBP
• Gene ID: 3394
• mRNA Refseq: NM_002163
• Protein Refseq: NP_002154
• MIM: 601565
• UniProt ID: Q02556