|Official Full Name||K(lysine) acetyltransferase 2A|
|Background||KAT2A, or GCN5, is a histone acetyltransferase (HAT) that functions primarily as a transcriptional activator. It also;functions as a repressor of NF-kappa-B (see MIM 164011) by promoting ubiquitination of the NF-kappa-B subunit RELA;(MIM 164014) in a HAT-independent manner (Mao et al., 2009 (PubMed 19339690)).|
|Synonyms||KAT2A; K(lysine) acetyltransferase 2A; GCN5 general control of amino acid synthesis 5 like 2 (yeast) , GCN5L2; histone acetyltransferase KAT2A; GCN5; PCAF b; STAF97; hsGCN5; lysine acetyltransferase 2A; histone acetyltransferase GCN5; general control of a|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
KAT2A involved in several pathways and played different roles in them. We selected most pathways KAT2A participated on our site, such as content, which may be useful for your reference. Also, other proteins which involved in the same pathway with KAT2A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Notch signaling pathway||ADAM17; ADAM17A; DTX4; TUBB3; DTX3L; PSEN2; PSEN1; MAML2; LFNG; NUMB|
|Thyroid hormone signaling pathway||MED12L; PRKCG; PIK3CA; PRKACB; PIK3R5; PIK3CG; MED27; GSK3B; NCOA3; PLCE1|
|HTLV-I infection||ETS2; FZD5; LTA; WNT1; HLA-DQA1; KRAS; ANAPC4; WNT9A; H2-AB1; HLA-DMA|
|Viral carcinogenesis||UBE3A; EP300; HIST1H2BO; CCNE1; HIST1H2BF; HIST1H4G; GTF2H1; PIK3CD; KAT2B; GTF2H4|
KAT2A has several biochemical functions, for example, Content. Some of the functions are cooperated with other proteins, some of the functions could acted by KAT2A itself. We selected most functions KAT2A had, and list some proteins which have the same functions with KAT2A. You can find most of the proteins on our site.
|H3 histone acetyltransferase activity||KAT2A; ELP3; BRCA2|
|chromatin binding||POLR2B; PHF8; SMC1A; HDAC7A; CHAF1A; NR5A1; HDGF2; PAF1; TRP63; HESX1|
|histone acetyltransferase activity||CLOCK; METTL8; NCOA1; HAT1; NCOA2; CREBBP; KAT7; KAT5; KAT8; KAT2B|
|contributes_to histone acetyltransferase activity||TAF5L; KAT2A; TAF10; TADA1; TAF6L; TAF12; TADA2B; TADA3; KAT5; ELP4|
|histone acetyltransferase activity (H4-K12 specific)||KAT2A|
|histone deacetylase binding||HES1; NKX3; SOD3; ZNF703; PKN2; SFPQ; PKN1; RUNX2; TFAP4; RFXANK|
|protein binding||IST1; BMPR2; MED1; FRMD4B; MMP14; RRP8; ABCB1; PRPF4B; DYNLT1; TEK|
|protein phosphatase binding||EGFR; ANAPC7; STAT6; GRB2; TRP53; JUP; CTNNB1; CDC27; TRAF2; PARD3|
|transcription coactivator activity||PRMT2; MED14; RFXAP; FUS; SOX17; GABPA; MTA1; WWTR1; SUPT7L; NR1H4|
|transcription factor binding||TFDP1; ID1; SIX2; TAF12; GTF2F1; BCOR; PER1; TFDP1B; NKX3-1; NR0B2A|
KAT2A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KAT2A here. Most of them are supplied by our site. Hope this information will be useful for your research of KAT2A.
TRRAP; WDHD1; ATXN7; BRCA1