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KAT2A

  • Official Full Name

    K(lysine) acetyltransferase 2A

  • Overview

    KAT2A, or GCN5, is a histone acetyltransferase (HAT) that functions primarily as a transcriptional activator. It also;functions as a repressor of NF-kappa-B (see MIM 164011) by promoting ubiquitination of the NF-kappa-B subunit RELA;(MIM 164014) in a HAT-independent manner (Mao et al., 2009 (PubMed 19339690)).
  • Synonyms

    KAT2A; K(lysine) acetyltransferase 2A; GCN5 general control of amino acid synthesis 5 like 2 (yeast) , GCN5L2; histone acetyltransferase KAT2A; GCN5; PCAF b; STAF97; hsGCN5; lysine acetyltransferase 2A; histone acetyltransferase GCN5; general control of a;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Human
  • Human
  • E. coli
  • E.coli
  • HEK293
  • Human
  • In Vitro Cell Free System
  • Insect cell
  • Insect Cell
  • Insect Cells
  • Sf21 Insect Cell
  • Sf9 Insect Cell
  • Wheat Germ
  • GST
  • His
  • Myc|DDK
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human KAT2A-274H Active Recombinant Human KAT2A, His-tagged Sf21 Insect Cell His
Human KAT2A-1392H Active Recombinant Human KAT2A, GST-tagged Sf9 Insect Cell GST 323 aa-end
Human KAT2A-18H Recombinant Human KAT2A Protein, GST-tagged E.coli GST
Human KAT2A-29886TH Recombinant Human KAT2A, His-tagged E.coli His 427 amino acids
Human KAT2A-120H Recombinant Human KAT2A Protein, GST-tagged E.coli GST 726-837
Human KAT2A-121H Recombinant Human KAT2A(497-662) Protein E. coli 497-662 aa
Human KAT2A-1017H Recombinant Human KAT2A, His-tagged Human His
Human KAT2A-2132H Recombinant Human KAT2A protein, GST-tagged Wheat Germ GST
Human KAT2A-2129H Recombinant Human K(lysine) Acetyltransferase 2A, His-tagged Insect Cell His
Human KAT2A-290HCL Recombinant Human KAT2A HEK293T cell lysate HEK293 Myc/DDK
Human KAT2A-058H Recombinant Human KAT2A Protein, His-tagged Insect cell His 2-837
Human KAT2A-005H Recombinant Human KAT2A Protein, His-tagged Insect Cells His 2-837
Human KAT2A-679HF Recombinant Full Length Human KAT2A Protein, GST-tagged In Vitro Cell Free System GST 837 amino acids
Human KAT2A-2352H Recombinant Human KAT2A Protein, His-tagged E.coli N-His Ala648-Lys837
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • KAT2A Related Research Area

KAT2A involved in several pathways and played different roles in them. We selected most pathways KAT2A participated on our site, such as Notch signaling pathway, Thyroid hormone signaling pathway, HTLV-I infection, which may be useful for your reference. Also, other proteins which involved in the same pathway with KAT2A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Notch signaling pathwayNOTCH1;ADAM17;NOTCH1A;DTX3;MARK2;MFAP5;DTX2;RBPJA;TUBB3
Thyroid hormone signaling pathwayPIK3CB;PRKACG;SLC9A1;MAP2K2;SLC16A10;PIK3CA;PIK3CD;ATP1A1;HRAS
HTLV-I infectionPPP3CA;BCL2L1;DLG1;MAP3K14;HLA-DRA;PPP3CB;IL15RA;SLC25A6;PDGFRB
Viral carcinogenesisC3;RB1;MAD1L1;SND1;GTF2A1L;KRAS;ACTN1;HDAC4;HIST1H4E

KAT2A has several biochemical functions, for example, H3 histone acetyltransferase activity, chromatin binding, histone acetyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by KAT2A itself. We selected most functions KAT2A had, and list some proteins which have the same functions with KAT2A. You can find most of the proteins on our site.

Function Related Protein
H3 histone acetyltransferase activityKAT2A;BRCA2;ELP3
chromatin bindingRERE;NUP62;Trl;HDGF2;SUV39H1;LDB1;ATAD2;TRP63;OVOL2
histone acetyltransferase activityTAF1;KAT6B;EP300;KAT7B;CDYL;KAT2B;HTATIP;vnc;KAT5
contributes_to histone acetyltransferase activityTEX30;EPC1;ELP4;KAT2A;SUPT7L;KAT5;TAF12;SAP130;TAF9
histone acetyltransferase activity (H4-K12 specific)
histone deacetylase bindingHOXA10;BRMS1L;MAGEA2;RAD9;HDAC5;DDX20;HEY2;HDAC10;NRIP1
protein bindingTYRP1;KRTAP9-4;SIN3B;C3orf39;CA4;ITGB1;SPRED1;IMP4;CNNM3
protein phosphatase bindingVCAN;MAP3K5;MAPK14;CDC27;FGF19;NEK2;DLG3;HSP90B1;Itga10&Itgb1
transcription coactivator activityTAF11;CCNE1;TUBB3;SERTAD2;TADA2A;ARID1A;PIAS1;ARL2BP;LPIN3
transcription factor bindingZFPM1;PAXBP1;E2F1;SOX8;PPP1R13BB;JUNBA;NLK;GTF2A1;NFATC2

KAT2A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KAT2A here. Most of them are supplied by our site. Hope this information will be useful for your research of KAT2A.

TRRAP; WDHD1; ATXN7; BRCA1

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