KAT2A

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KAT2A

Official Full Name K(lysine) acetyltransferase 2A
Background KAT2A, or GCN5, is a histone acetyltransferase (HAT) that functions primarily as a transcriptional activator. It also;functions as a repressor of NF-kappa-B (see MIM 164011) by promoting ubiquitination of the NF-kappa-B subunit RELA;(MIM 164014) in a HAT-independent manner (Mao et al., 2009 (PubMed 19339690)).
Synonyms KAT2A; K(lysine) acetyltransferase 2A; GCN5 general control of amino acid synthesis 5 like 2 (yeast) , GCN5L2; histone acetyltransferase KAT2A; GCN5; PCAF b; STAF97; hsGCN5; lysine acetyltransferase 2A; histone acetyltransferase GCN5; general control of a
    • Species :
    • Human
    • Source :
    • E.coli
    • HEK293
    • Human
    • Insect Cell
    • Sf21 Insect Cell
    • Sf9 Insect Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • Myc
    • DDK
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human KAT2A-1017H Recombinant Human KAT2A, His-tagged Human His
    Human KAT2A-120H Recombinant Human KAT2A Protein, GST-tagged E.coli GST
    Human KAT2A-121H Recombinant Human KAT2A Protein, His-tagged E.coli His
    Human KAT2A-1392H Recombinant Human KAT2A (Active), GST-tagged Sf9 Insect Cell GST
    Human KAT2A-18H Recombinant Human KAT2A Protein, GST-tagged E.coli GST
    Human KAT2A-2129H Recombinant Human K(lysine) Acetyltransferase 2A, His-tagged Insect Cell His
    Human KAT2A-2132H Recombinant Human KAT2A protein, GST-tagged Wheat Germ GST
    Human KAT2A-274H Recombinant Human KAT2A, His-tagged Sf21 Insect Cell His
    Human KAT2A-290HCL Recombinant Human KAT2A HEK293T cell lysate HEK293 Myc/DDK
    Human KAT2A-29886TH Recombinant Human KAT2A, His-tagged E.coli His

    KAT2A involved in several pathways and played different roles in them. We selected most pathways KAT2A participated on our site, such as content, which may be useful for your reference. Also, other proteins which involved in the same pathway with KAT2A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Notch signaling pathway ADAM17; ADAM17A; DTX4; TUBB3; DTX3L; PSEN2; PSEN1; MAML2; LFNG; NUMB
    Thyroid hormone signaling pathway MED12L; PRKCG; PIK3CA; PRKACB; PIK3R5; PIK3CG; MED27; GSK3B; NCOA3; PLCE1
    HTLV-I infection ETS2; FZD5; LTA; WNT1; HLA-DQA1; KRAS; ANAPC4; WNT9A; H2-AB1; HLA-DMA
    Viral carcinogenesis UBE3A; EP300; HIST1H2BO; CCNE1; HIST1H2BF; HIST1H4G; GTF2H1; PIK3CD; KAT2B; GTF2H4

    KAT2A has several biochemical functions, for example, Content. Some of the functions are cooperated with other proteins, some of the functions could acted by KAT2A itself. We selected most functions KAT2A had, and list some proteins which have the same functions with KAT2A. You can find most of the proteins on our site.

    Function Related Protein
    H3 histone acetyltransferase activity KAT2A; ELP3; BRCA2
    chromatin binding POLR2B; PHF8; SMC1A; HDAC7A; CHAF1A; NR5A1; HDGF2; PAF1; TRP63; HESX1
    histone acetyltransferase activity CLOCK; METTL8; NCOA1; HAT1; NCOA2; CREBBP; KAT7; KAT5; KAT8; KAT2B
    contributes_to histone acetyltransferase activity TAF5L; KAT2A; TAF10; TADA1; TAF6L; TAF12; TADA2B; TADA3; KAT5; ELP4
    histone acetyltransferase activity (H4-K12 specific) KAT2A
    histone deacetylase binding HES1; NKX3; SOD3; ZNF703; PKN2; SFPQ; PKN1; RUNX2; TFAP4; RFXANK
    protein binding IST1; BMPR2; MED1; FRMD4B; MMP14; RRP8; ABCB1; PRPF4B; DYNLT1; TEK
    protein phosphatase binding EGFR; ANAPC7; STAT6; GRB2; TRP53; JUP; CTNNB1; CDC27; TRAF2; PARD3
    transcription coactivator activity PRMT2; MED14; RFXAP; FUS; SOX17; GABPA; MTA1; WWTR1; SUPT7L; NR1H4
    transcription factor binding TFDP1; ID1; SIX2; TAF12; GTF2F1; BCOR; PER1; TFDP1B; NKX3-1; NR0B2A

    KAT2A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KAT2A here. Most of them are supplied by our site. Hope this information will be useful for your research of KAT2A.

    TRRAP; WDHD1; ATXN7; BRCA1

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