Active Recombinant Human KAT2A, His-tagged
Cat.No. : | KAT2A-274H |
Product Overview : | Human GCN5 is fused to a His-tag. |
- Specification
- Gene Information
- Related Products
Description : | GCN5 functions as a histone acetyltransferase (HAT) to promote transcriptional activation. Acetylation of histones gives a specific tag for epigenetic transcription activation. It has significant histone acetyltransferase activity with core histones, but not with nucleosome core particles. In case of HIV-1 infection, it is recruited by the viral protein Tat. It regulates Tats transactivating activity and may help inducing chromatin remodeling of proviral genes. GCN5 is a component of the Ada Two-A containing (ATAC) complex, a complex with histone acetyltransferase activity on histones H3 and H4. |
Source : | Baculovirus infected Sf21 Cells |
Species : | Human |
Tag : | His |
Form : | Liquid. In 50mM TRIS-HCl, pH 7.5, containing 100mM sodium chloride, 0.2% NP-40, 50mM imidazole and 10% glycerol. |
Bio-activity : | ~200-300ng are required for standard HAT assay. |
Purity : | ≥95% (SDS-PAGE) |
Stability : | Stable for at least 6 months after receipt when stored at -80°C. |
Storage : | Short Term Storage: -20°C; Long Term Storage: -80°C. After opening, prepare aliquots and store at -80°C. Avoid freeze/thaw cycles. |
Concentration : | Lot dependent (0.2-0.5mg/ml) |
Gene Name : | KAT2A K(lysine) acetyltransferase 2A [ Homo sapiens ] |
Official Symbol : | KAT2A |
Synonyms : | KAT2A; K(lysine) acetyltransferase 2A; GCN5 general control of amino acid synthesis 5 like 2 (yeast) , GCN5L2; histone acetyltransferase KAT2A; GCN5; PCAF b; STAF97; hsGCN5; lysine acetyltransferase 2A; histone acetyltransferase GCN5; general control of amino acid synthesis protein 5-like 2; General control of amino acid synthesis, yeast, homolog-like 2; GCN5 (general control of amino-acid synthesis, yeast, homolog)-like 2; hGCN5; GCN5L2; PCAF-b; MGC102791; |
Gene ID : | 2648 |
mRNA Refseq : | NM_021078 |
Protein Refseq : | NP_066564 |
MIM : | 602301 |
UniProt ID : | Q92830 |
Chromosome Location : | 17q12-q21 |
Pathway : | C-MYC pathway, organism-specific biosystem; E2F transcription factor network, organism-specific biosystem; Gene Expression, organism-specific biosystem; Generic Transcription Pathway, organism-specific biosystem; HTLV-I infection, organism-specific biosystem; HTLV-I infection, conserved biosystem; NOTCH1 Intracellular Domain Regulates Transcription, organism-specific biosystem; |
Function : | H3 histone acetyltransferase activity; chromatin binding; histone acetyltransferase activity; contributes_to histone acetyltransferase activity; histone acetyltransferase activity (H4-K12 specific); histone deacetylase binding; protein binding; transcription coactivator activity; transferase activity; |
Products Types
◆ Recombinant Protein | ||
KAT2A-058H | Recombinant Human KAT2A Protein, His-tagged | +Inquiry |
KAT2A-005H | Recombinant Human KAT2A Protein, His-tagged | +Inquiry |
KAT2A-2352H | Recombinant Human KAT2A Protein, His-tagged | +Inquiry |
KAT2A-18H | Recombinant Human KAT2A Protein, GST-tagged | +Inquiry |
KAT2A-2129H | Recombinant Human K(lysine) Acetyltransferase 2A, His-tagged | +Inquiry |
◆ Lysates | ||
KAT2A-290HCL | Recombinant Human KAT2A HEK293T cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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