Recombinant Human KAT2A Protein, His-tagged

• Cat.No.: KAT2A-005H
• Product Overview: Recombinant Human KAT2A protein (2-837)with a N-terminal His-tag was expressed in Sf21 cells

Specification

• Description: KAT2A, or GCN5, is a histone acetyltransferase (HAT) that functions primarily as a transcriptional activator. It also functions as a repressor of NF-kappa-B by promoting ubiquitination of the NF-kappa-B subunit RELA in a HAT-independent manner.
• Source: Insect Cells
• Species: Human
• Tag: His
• Molecular Mass: 96.3 kDa
• Protein length: 2-837
• Purity: ≥50 % (estimated by SDS-PAGE)
• Unit Definition: One unit is defined as the amount of enzyme required to convert 1 nmol of acetyl-CoA to reduced Coenzyme A (CoASH) per minute at 37 centigrade in 100 mM HEPES, pH 7.5, containing 0.8% polysorbate 20. CoASH produced in the reaction is measured fluorometrically using HAT Inhibitor Screening Assay Kit with 100 µM histone H3 peptide (1-21) as the acetyl acceptor.
• Stability: ≥ 2 years
• Storage: -80 centigrade
• Storage Buffer: 50 mM Tris-HCl, pH 8.0, containing 150 mM sodium chloride and 20% glycerol
• Shipping: Dry ice in continental US, may vary elsewhere.

Gene Information

• Gene Name: KAT2A lysine acetyltransferase 2A [ Homo sapiens (human) ]
• Official Symbol: KAT2A
• Synonyms: KAT2A; lysine acetyltransferase 2A; GCN5; hGCN5; GCN5L2; PCAF-b; histone acetyltransferase KAT2A; GCN5 (general control of amino-acid synthesis, yeast, homolog)-like 2; General control of amino acid synthesis, yeast, homolog-like 2 K(lysine) acetyltransferase 2A; STAF97; general control of amino acid synthesis protein 5-like 2; histone acetyltransferase GCN5; histone glutaryltransferase KAT2A; histone succinyltransferase KAT2A; hsGCN5; EC 2.3.1.48
• Gene ID: 2648
• mRNA Refseq: NM_021078
• Protein Refseq: NP_066564
• MIM: 602301
• UniProt ID: Q92830