KLK8

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KLK8

Official Full Name kallikrein-related peptidase 8
Background Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in tandem in a gene cluster on chromosome 19. The encoded protein may be involved in proteolytic cascade in the skin and may serve as a biomarker for ovarian cancer. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013]
Synonyms KLK8; kallikrein-related peptidase 8; NP; HNP; NRPN; PRSS19; TADG14; kallikrein-8; ovasin; serine protease 19; serine protease TADG-14; tumor-associated differentially expressed gene 14 protein; BSP1
    • Species :
    • Human
    • Mouse
    • Rat
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Human Cell
    • Mammalian Cell
    • NS0
    • Sf9 Insect Cell
    • Wheat Germ
    • Yeast
    • Tag :
    • DDK
    • GST
    • His
    • T7
    • Myc/DDK
    • Myc
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Mouse KLK8-2157M Recombinant Mouse KLK8 Protein (33-260 aa), His-tagged Yeast His
    Mouse Klk8-3727M Recombinant Mouse Klk8 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Human KLK8-480H Recombinant Human KLK8 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human KLK8-1166H Recombinant Human KLK8, His tagged Human Cell His
    Human KLK8-1985HCL Recombinant Human KLK8 cell lysate Human Cell N/A
    Human KLK8-462H Recombinant Human KLK8 Protein, DDK-tagged Sf9 Insect Cell DDK
    Human KLK8-4928H Recombinant Human KLK8 Protein, GST-tagged Wheat Germ GST
    Human KLK8-688H Recombinant Human KLK8 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human KLK8-797H Recombinant Human KLK8 protein, His & T7-tagged E.coli His/T7
    Human KLK8-998H Recombinant Human KLK8 Protein, His-tagged NS0 His
    Mouse Klk8-798M Recombinant Mouse Klk8 protein, His & GST-tagged E.coli His/GST
    Mouse KLK8-8755M Recombinant Mouse KLK8 Protein Mammalian Cell His
    Rat Klk8-799R Recombinant Rat Klk8 protein, His & GST-tagged E.coli His/GST

    KLK8 involved in several pathways and played different roles in them. We selected most pathways KLK8 participated on our site, such as Spinal Cord Injury, which may be useful for your reference. Also, other proteins which involved in the same pathway with KLK8 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Spinal Cord Injury OMG; GDNF; TNFSF13B; RTN4R; AIF1; LGALS3; GAP43; NOX4; RTN4; RGMA

    KLK8 has several biochemical functions, for example, protein binding, serine-type endopeptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by KLK8 itself. We selected most functions KLK8 had, and list some proteins which have the same functions with KLK8. You can find most of the proteins on our site.

    Function Related Protein
    protein binding PCBP1; UBQLN4; GAPDH; LPP; KHK; ERRFI1; MAP1S; RFWD3; RND2; CD226
    serine-type endopeptidase activity IMMP1L; PRSS7; KLK1B11; TMPRSS4; TMPRSS11G; CTRL; PRSS27; PRSS57; KLK1B4; KLK6

    KLK8 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KLK8 here. Most of them are supplied by our site. Hope this information will be useful for your research of KLK8.

    NOTCH2NL; ZDHHC17; RGS2

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