micb
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  • Official Full Name
  • MHC class I polypeptide-related sequence B
  • Background
  • MICA and MICB (Major Histocompatibility Complex class I Chain-related gene A and gene B) bind to the activating immunoreceptor NKG2D. NKG2D is expressed on NK (Natural Killer) cells, NKT cells, ??T cells and CD8+??T cells. Recognition of MICA and MICB by
  • Synonyms
  • MICB; MHC class I polypeptide-related sequence B; PERB11.2; MIC-B; MHC class I mic-B antigen; stress inducible class I homolog; MHC class I chain-related protein B; MHC class I-like molecule PERB11.2-IMX
Cat.#:MICB-2051HTag:Fc|His
Source (Host):HEK293Species:Human
Product nameRecombinant Human MICB Protein, Fc/His-tagged
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Cat.#:MICB-1231HTag:Myc|DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human MICB Protein, MYC/DDK-tagged
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Cat.#:MICB-5326HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human MICB Protein, GST-tagged
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Cat.#:MICB-5454HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human MHC Class I Polypeptide-Related Sequence B
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Cat.#:MICB-08HTag:N/A
Source (Host):E.coliSpecies:Human
Product nameRecombinant Human MICB protein
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Cat.#:MICB-520HTag:Fc Chimera
Source (Host):NSO cellsSpecies:Human
Product nameRecombinant Human MICB, Fc Chimera
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Cat.#:MICB-807HTag:Fc|His
Source (Host):HEK293Species:Human
Product nameRecombinant Human MICB, Fc-His tagged
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Cat.#:MICB-808HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human MICB, His tagged
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Cat.#:MICB-2769RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey MICB Protein, His-tagged
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Cat.#:MICB-5194HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human MHC Class I Polypeptide-Related Sequence B
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Cat.#:MICB-2712HCLTag:N/A
Source (Host):HEK293Species:Human
Product nameRecombinant Human MICB cell lysate
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Cat.#:MICB-2885HCLTag:N/A
Source (Host):HEK293Species:Human
Product nameRecombinant Human MICB cell lysate
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Involved Pathway

MICB involved in several pathways and played different roles in them. We selected most pathways MICB participated on our site, such as Natural killer cell mediated cytotoxicity, which may be useful for your reference. Also, other proteins which involved in the same pathway with MICB were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Natural killer cell mediated cytotoxicity
KLRC1; TYROBP; Raet1c; MAPK1; PTPN6; NCR2; KIR2DS2; TNFRSF10B; VAV3; IFNA4

Protein Function

MICB has several biochemical functions, for example, natural killer cell lectin-like receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MICB itself. We selected most functions MICB had, and list some proteins which have the same functions with MICB. You can find most of the proteins on our site.
Function
Related Protein
Function natural killer cell lectin-like receptor binding
Related Protein H60a; ULBP3; Raet1a; RAET1D; ULBP1; RAET1E; Raet1c; ULBP2; CLEC2H; MICB

MICB Related Articles

Amin, PJ; Shankar, BS; et al. Sulforaphane induces ROS mediated induction of NKG2D ligands in human cancer cell lines and enhances susceptibility to NK cell mediated lysis. LIFE SCIENCES 126:19-27(2015).
Nowroozpoor-Dailami, K; Mirabi, AM; et al. Aqueous Humor and Serum Concentrations of Soluble MICA and MICB in Glaucoma Patients. IRANIAN JOURNAL OF IMMUNOLOGY 11:275-281(2014).