Recombinant Human MICB protein, His-Avi-tagged, Biotinylated

• Cat.No.: MICB-980HB
• Product Overview: Biotinylated Rcombinant Human MICB Protein is expressed from mammalian with His and Avi Tag at the C-terminal. It contains Ala23-Gly298.

Specification

• Description: MICB (MHC class I chain-related gene B) is a transmembrane glycoprotein that functions as a ligand for NKG2D. A closely related protein, MICA, shares 85% amino acid identity with MICB. MICB Seems to have no role in antigen presentation. Acts as a stress-induced self-antigen that is recognized by gamma delta T cells. Ligand for the KLRK1/NKG2D receptor. Binding to KLRK1 leads to cell lysis.
• Source: HEK293
• Species: Human
• Tag: His-Avi
• Form: Supplied as 0.22μm filtered solution in PBS(pH 7.4).
• Molecular Mass: The protein has a predicted MW of 34.4KDa. Due to glycosylation, the protein migrates to 48-65KDa based on Bis-Tris PAGE result.
• Protein length: Ala23-Gly298
• Endotoxin: Less than 0.05EU per μg by the LAL method.
• Purity: >95% as determined by HPLC; >95% as determined by Tris-Bis PAG
• Storage: The product should be stored at -70°C. Please do not repeated freeze-thaw cycles.

Gene Information

• Gene Name: MICB
• Official Symbol: MICB
• Synonyms: MHC class I chain-related protein B; MHC class I mic-B antigen; MHC class I polypeptide-related sequence B; MICB; MIC-B; PERB11.2MHC class I-like molecule PERB11.2-IMX; stress inducible class I homolog
• Gene ID: 4277
• mRNA Refseq: NM_001289160.1
• Protein Refseq: NP_001276089.1
• MIM: 602436
• UniProt ID: Q29980