mrc2
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  • Official Full Name
  • mannose receptor, C type 2
  • Background
  • MRC2 is a recycling endocytic receptor that functions in cell motility and remodeling of the extracellular matrix by promoting cell migration and uptake of collagens for intracellular degradation (Wienke et al., 2007
  • Synonyms
  • MRC2; mannose receptor, C type 2; C-type mannose receptor 2; CD280; CLEC13E; ENDO180; KIAA0709; C-type lectin domain family 13 member E; CD 280; CD280 antigen; CLEC 13E; ENDO 180; Endocytic receptor (macrophage mannose receptor family); Endocytic receptor 180; FLJ35911; Macrophage mannose receptor 2; Mannose receptor C type 2; MRC 2; MRC2_HUMAN; UPAR-associated protein; UPARAP; Urokinase plasminogen activator receptor associated protein; Urokinase receptor associated protein; Urokinase receptor-associated protein; Urokinase-type plasminogen activator receptor-associated protein; urokinase plasmino
Cat.#:MRC2-22HTag:Myc|DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human MRC2 Protein, MYC/DDK-tagged
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Cat.#:MRC2-5535HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human MRC2 Protein, GST-tagged
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Cat.#:MRC2-1133HTag:His
Source (Host):Mammalian CellsSpecies:Human
Product nameRecombinant Human MRC2
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Cat.#:MRC2-29703THTag:N/A
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human MRC2
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Cat.#:MRC2-825HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human MRC2 protein, His-tagged
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Cat.#:MRC2-3747RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat MRC2 Protein
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Involved Pathway

MRC2 involved in several pathways and played different roles in them. We selected most pathways MRC2 participated on our site, such as Phagosome, Tuberculosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with MRC2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Phagosome
ATP6V0A4; ITGB1; TUBA1C; Cd209g; ATP6V1F; ITGB2L; TUBA8; TUBA8L; PIK3C3; THBS4
Tuberculosis
MAPK9; TRAF6; IL1A; KSR1; TLR4; CALM3; IL12A; FCGR2C; Il23a; Il12b; NOS2

Protein Function

MRC2 has several biochemical functions, for example, carbohydrate binding, collagen binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MRC2 itself. We selected most functions MRC2 had, and list some proteins which have the same functions with MRC2. You can find most of the proteins on our site.
Function
Related Protein
Function carbohydrate binding
Related Protein GALNT5; LAYN; SIGLEC12; GANC; KRT1; KLRB1B; LGALS2A; MAN2A2; PKD1; GALNTL6
Function collagen binding
Related Protein CTSB; Itga10&Itgb1; HSD17B12; Pdgfa&Pdgfb; LRRC15; LUM; DDR2; CTSK; ITGA9; MMP9
Function protein binding
Related Protein ZFP423; SEMA4D; CUBN; PYYA; TAF3; PRKCQ; BBS7; DUSP12; HAPLN2; GFI1

Interacting Protein

MRC2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MRC2 here. Most of them are supplied by our site. Hope this information will be useful for your research of MRC2.
PPM1D; XRCC3; BAG4; RAF1; PTPN1; AKT1; PAX2; PALB2; RB1CC1; ESR2; NDEL1; BRMS1