| Description : |
This gene encodes a member of the mannose receptor family of proteins that contain a fibronectin type II domain and multiple C-type lectin-like domains. The encoded protein plays a role in extracellular matrix remodeling by mediating the internalization and lysosomal degradation of collagen ligands. Expression of this gene may play a role in the tumorigenesis and metastasis of several malignancies including breast cancer, gliomas and metastatic bone disease. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
166.5 kDa |
| AA Sequence : |
MGPGRPAPAPWPRHLLRCVLLLGCL HLGRPGAPGDAALPEPNVFLIFSHG LQGCLEAQGGQVRVTPACNTSLPAQ RWKWVSRNRLFNLGTMQCLGTGWPG TNTTASLGMYECDREALNLRWHCRT LGDQLSLLLGARTSNISKPGTLERG DQTRSGQWRIYGSEEDLCALPYHEV YTIQGNSHGKPCTIPFKYDNQWFHG CTSTGREDGHLWCATTQDYGKDERW GFCPIKSNDCETFWDKDQLTDSCYQ FNFQSTLSWREAWASCEQQGADLLS ITEIHEQTYINGLLTGYSSTLWIGL NDLDTSGGWQWSDNSPLKYLNWESD QPDNPSEENCGVIRTESSGGWQNRD CSIALPYVCKKKPNATAEPTPPDRW ANVKVECEPSWQPFQGHCYRLQAEK RSWQESKKACLRGGGDLVSIHSMAE LEFITKQIKQEVEELWIGLNDLKLQ MNFEWSDGSLVSFTHWHPFEPNNFR DSLEDCVTIWGPEGRWNDSPCNQSL PSICKKAGQLSQGAAEEDHGCRKGW TWHSPSCYWLGEDQVTYSEARRLCT DHGSQLVTITNRFEQAFVSSLIYNW EGEYFWTALQDLNSTGSFFWLSGDE VMYTHWNRDQPGYSRGGCVALATGS AMGLWEVKNCTSFRARYICRQSLGT PVTPELPGPDPTPSLTGSCPQGWAS DTKLRYCYKVFSSERLQDKKSWVQA QGACQELGAQLLSLASYEEEHFVAN MLNKIFGESEPEIHEQHWFWIGLNR RDPRGGQSWRWSDGVGFSYHNFDRS RHDDDDIRGCAVLDLASLQWVAMQC DTQLDWICKIPRGTDVREPDDSPQG RREWLRFQEAEYKFFEHHSTWAQAQ RICTWFQAELTSVHSQAELDFLSHN LQKFSRAQEQHWWIGLHTSESDGRF RWTDGSIINFISWAPGKPRPVGKDK KCVYMTASREDWGDQRCLTALPYIC KRSNVTKETQPPDLPTTALGGCPSD WIQFLNKCFQVQGQEPQSRVKWSEA QFSCEQQEAQLVTITNPLEQAFITA SLPNVTFDLWIGLHASQRDFQWVEQ EPLMYANWAPGEPSGPSPAPSGNKP TSCAVVLHSPSAHFTGRWDDRSCTE ETHGFICQKGTDPSLSPSPAALPPA PGTELSYLNGTFRLLQKPLRWHDAL LLCESHNASLAYVPDPYTQAFLTQA ARGLRTPLWIGLAGEEGSRRYSWVS EEPLNYVGWQDGEPQQPGGCTYVDV DGAWRTTSCDTKLQGAVCGVSSGPP PPRRISYHGSCPQGLADSAWIPFRE HCYSFHMELLLGHKEARQRCQRAGG AVLSILDEMENVFVWEHLQSYEGQS RGAWLGMNFNPKGGTLVWQDNTAVN YSNWGPPGLGPSMLSHNSCYWIQSN SGLWRPGACTNITMGVVCKLPRAEQ SSFSPSALPENPAALVVVLMAVLLL LALLTAALILYRRRQSIERGAFEGA RYSRSSSSPTEATEKNILVSDMEMN EQQETRTRPLEQKLISEEDLAANDI LDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
