Recombinant Full Length Human MRC2 Protein, C-Flag-tagged

• Cat.No.: MRC2-515HFL
• Product Overview: Recombinant Full Length Human MRC2 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene encodes a member of the mannose receptor family of proteins that contain a fibronectin type II domain and multiple C-type lectin-like domains. The encoded protein plays a role in extracellular matrix remodeling by mediating the internalization and lysosomal degradation of collagen ligands. Expression of this gene may play a role in the tumorigenesis and metastasis of several malignancies including breast cancer, gliomas and metastatic bone disease.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 166.5 kDa
• AA Sequence: MGPGRPAPAPWPRHLLRCVLLLGCL HLGRPGAPGDAALPEPNVFLIFSHG LQGCLEAQGGQVRVTPACNT SLPAQRWKWVSRNRLFNLGTMQCLG TGWPGTNTTASLGMYECDREALNLR WHCRTLGDQLSLLLGARTSN ISKPGTLERGDQTRSGQWRIYGSEE DLCALPYHEVYTIQGNSHGKPCTIP FKYDNQWFHGCTSTGREDGH LWCATTQDYGKDERWGFCPIKSNDC ETFWDKDQLTDSCYQFNFQSTLSWR EAWASCEQQGADLLSITEIH EQTYINGLLTGYSSTLWIGLNDLDT SGGWQWSDNSPLKYLNWESDQPDNP SEENCGVIRTESSGGWQNRD CSIALPYVCKKKPNATAEPTPPDRW ANVKVECEPSWQPFQGHCYRLQAEK RSWQESKKACLRGGGDLVSI HSMAELEFITKQIKQEVEELWIGLN DLKLQMNFEWSDGSLVSFTHWHPFE PNNFRDSLEDCVTIWGPEGR WNDSPCNQSLPSICKKAGQLSQGAA EEDHGCRKGWTWHSPSCYWLGEDQV TYSEARRLCTDHGSQLVTIT NRFEQAFVSSLIYNWEGEYFWTALQ DLNSTGSFFWLSGDEVMYTHWNRDQ PGYSRGGCVALATGSAMGLW EVKNCTSFRARYICRQSLGTPVTPE LPGPDPTPSLTGSCPQGWASDTKLR YCYKVFSSERLQDKKSWVQA QGACQELGAQLLSLASYEEEHFVAN MLNKIFGESEPEIHEQHWFWIGLNR RDPRGGQSWRWSDGVGFSYH NFDRSRHDDDDIRGCAVLDLASLQW VAMQCDTQLDWICKIPRGTDVREPD DSPQGRREWLRFQEAEYKFF EHHSTWAQAQRICTWFQAELTSVHS QAELDFLSHNLQKFSRAQEQHWWIG LHTSESDGRFRWTDGSIINF ISWAPGKPRPVGKDKKCVYMTASRE DWGDQRCLTALPYICKRSNVTKETQ PPDLPTTALGGCPSDWIQFL NKCFQVQGQEPQSRVKWSEAQFSCE QQEAQLVTITNPLEQAFITASLPNV TFDLWIGLHASQRDFQWVEQ EPLMYANWAPGEPSGPSPAPSGNKP TSCAVVLHSPSAHFTGRWDDRSCTE ETHGFICQKGTDPSLSPSPA ALPPAPGTELSYLNGTFRLLQKPLR WHDALLLCESHNASLAYVPDPYTQA FLTQAARGLRTPLWIGLAGE EGSRRYSWVSEEPLNYVGWQDGEPQ QPGGCTYVDVDGAWRTTSCDTKLQG AVCGVSSGPPPPRRISYHGS CPQGLADSAWIPFREHCYSFHMELL LGHKEARQRCQRAGGAVLSILDEME NVFVWEHLQSYEGQSRGAWL GMNFNPKGGTLVWQDNTAVNYSNWG PPGLGPSMLSHNSCYWIQSNSGLWR PGACTNITMGVVCKLPRAEQ SSFSPSALPENPAALVVVLMAVLLL LALLTAALILYRRRQSIERGAFEGA RYSRSSSSPTEATEKNILVS
  DMEMNEQQETRTRPLEQKLISEEDL AANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome, Transmembrane

Gene Information

• Gene Name: MRC2 mannose receptor C type 2 [ Homo sapiens (human) ]
• Official Symbol: MRC2
• Synonyms: CD280; UPARAP; CLEC13E; ENDO180
• Gene ID: 9902
• mRNA Refseq: NM_006039.5
• Protein Refseq: NP_006030.2
• MIM: 612264
• UniProt ID: Q9UBG0