myl6
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  • Official Full Name
  • myosin, light chain 6, alkali, smooth muscle and non-muscle
  • Background
  • Myosin light polypeptide 6 is a protein that in humans is encoded by the MYL6 gene. Myosin is a hexameric ATPase cellular motor protein. It is composed of two heavy chains, two nonphosphorylatable alkali light chains, and two phosphorylatable regulatory light chains. This gene encodes a myosin alkali light chain that is expressed in smooth muscle and non-muscle tissues. Genomic sequences representing several pseudogenes have been described and two transcript variants encoding different isoforms have been identified for this gene
  • Synonyms
  • MYL6; myosin, light chain 6, alkali, smooth muscle and non-muscle; myosin, light polypeptide 6, alkali, smooth muscle and non muscle; myosin light polypeptide 6; ESMLC; MLC1SM; MLC3NM; myosin light chain A3; 17 kDa myosin light chain; myosin light chain a
Cat.#:MYL6-5814HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human MYL6 Protein, GST-tagged
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Cat.#:MYL6-30266THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human MYL6, His-tagged
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Cat.#:MYL6-30267THTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human MYL6
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Cat.#:MYL6-3446HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human MYL6 protein, His-tagged
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Cat.#:MYL6-10317MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse MYL6 Protein
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Cat.#:MYL6-2923RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey MYL6 Protein, His-tagged
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Cat.#:MYL6-1485ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish MYL6
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Cat.#:MYL6-4023HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human MYL6 293 Cell Lysate
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Cat.#:MYL6-4024HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human MYL6 293 Cell Lysate
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Involved Pathway

MYL6 involved in several pathways and played different roles in them. We selected most pathways MYL6 participated on our site, such as Vascular smooth muscle contraction, Oxytocin signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with MYL6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Vascular smooth muscle contraction
RAF1; PLA2G2A; CALD1; NPR2; MYLK4; RAF1B; PLA2G2F; RHOAD; CACNA1C; PLA2G4F
Oxytocin signaling pathway
PRKAG1; PLCB3; CALM3; GNAI3; PRKAA1; PIK3CG; GNAI1; PLA2G4A; GUCY1A3; CALML5

Protein Function

MYL6 has several biochemical functions, for example, actin-dependent ATPase activity, calcium ion binding, motor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by MYL6 itself. We selected most functions MYL6 had, and list some proteins which have the same functions with MYL6. You can find most of the proteins on our site.
Function
Related Protein
Function actin-dependent ATPase activity
Related Protein MYH7; MYO3A; MYH9; MYO1C; MYL6; MYH10; MYO7A; MYO1D
Function calcium ion binding
Related Protein DUOX2; PCDH2AB1; NELL1; SPARCL1; CD93; C2CD4A; MYL2B; SLIT2; PKD1L2; RCN1
Function motor activity
Related Protein MYO5A; MYH8; MYO6A; MYH6; DYNLT3; MYHZ1.2; SMYHC3; MYO5C; MYO1A; KIF18B
Function protein binding
Related Protein SLC7A1; SCGB2A2; RAPGEF4; METTL17; TBC1D10A; HEY2; PARP9; IGF1; RBM39; SYT17
Function structural constituent of muscle
Related Protein SYNM; MYLPF; MYL2; MYOM1; MYBPC3; MYL9; ACTN3; MYL6; CAPN3; NEBL

Interacting Protein

MYL6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MYL6 here. Most of them are supplied by our site. Hope this information will be useful for your research of MYL6.
ESR1; IKBKE; ADAMTS12; VCAM1; 1-phosphatidyl-1d-myo-inositol 3,5-bisphosphate; 1-phosphatidyl-1d-myo-inositol 4,5-bisphosphate; PPP2R2B; ESR2

MYL6 Related Articles

Yuan, SQ; Stratton, CJ; et al. Spata6 is required for normal assembly of the sperm connecting piece and tight head-tail conjunction. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 112:E430-E439(2015).
Tsai, CJ; Lin, YC; et al. Chemical derivatization combined with capillary LC or MALDI-TOF MS for trace determination of lipoic acid in cosmetics and integrated protein expression profiling in human keratinocytes. TALANTA 130:347-355(2014).