MYL6
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Official Full Name
myosin, light chain 6, alkali, smooth muscle and non-muscle
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Overview
Myosin light polypeptide 6 is a protein that in humans is encoded by the MYL6 gene. Myosin is a hexameric ATPase cellular motor protein. It is composed of two heavy chains, two nonphosphorylatable alkali light chains, and two phosphorylatable regulatory light chains. This gene encodes a myosin alkali light chain that is expressed in smooth muscle and non-muscle tissues. Genomic sequences representing several pseudogenes have been described and two transcript variants encoding different isoforms have been identified for this gene -
Synonyms
MYL6; myosin, light chain 6, alkali, smooth muscle and non-muscle; myosin, light polypeptide 6, alkali, smooth muscle and non muscle; myosin light polypeptide 6; ESMLC; MLC1SM; MLC3NM; myosin light chain A3; 17 kDa myosin light chain; myosin light chain a;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rhesus Macaque
- Zebrafish
- E.coli
- HEK293
- HEK293T
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- Myc
- DDK
- N/A
- N
- Involved Pathway
- Protein Function
- Interacting Protein
- MYL6 Related Articles
MYL6 involved in several pathways and played different roles in them. We selected most pathways MYL6 participated on our site, such as Vascular smooth muscle contraction, Oxytocin signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with MYL6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Vascular smooth muscle contraction | GUCY1A3;MYL12.1;PLA2G4D;PRKACB;PPP1R12C;MYL6B;MYH11;CYP4A14;ARHGEF1 |
| Oxytocin signaling pathway | PLA2G4C;NOS3;GNAQ;PRKAB2;CACNA2D4;PIK3R2;KCNJ14;MAP2K5;PLCB4 |
MYL6 has several biochemical functions, for example, actin-dependent ATPase activity, calcium ion binding, motor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by MYL6 itself. We selected most functions MYL6 had, and list some proteins which have the same functions with MYL6. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| actin-dependent ATPase activity | MYH7;MYH9;MYO1D;MYH10;MYO3A;MYO1C;MYO7A;MYL6 |
| calcium ion binding | SPOCK3;PCDHGA11;PCDH1A6;ANXA1;RYR3;EPD;AIF1;CAPN1;CAPN2 |
| motor activity | MYO6B;VMHCL;DNAIC2;SMYHC3;MYO1C;DYNLL1;DNAI1;MYO6;KIF2A |
| protein binding | GATA6;AIFM1;RAB3C;Apba1;TOR1B;NFE2L3;SAP30L;ABHD1;AMOTL2A |
| structural constituent of muscle | TPM1;ANKRD2;MYL6;MYL3;MYL1;CAPN3;JPH1;TPM2;CSRP3 |
MYL6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MYL6 here. Most of them are supplied by our site. Hope this information will be useful for your research of MYL6.
ESR1; IKBKE; ADAMTS12; VCAM1; 1-phosphatidyl-1d-myo-inositol 3,5-bisphosphate; 1-phosphatidyl-1d-myo-inositol 4,5-bisphosphate; PPP2R2B; ESR2
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