NCAM1
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Official Full Name
neural cell adhesion molecule 1 -
Overview
Neural Cell Adhesion Molecule (NCAM, also the cluster of differentiation CD56) is a homophilic binding glycoprotein expressed on the surface of neurons, glia, skeletal muscle and natural killer cells. NCAM has been implicated as having a role in cell–cell adhesion, neurite outgrowth, synaptic plasticity, and learning and memory. -
Synonyms
CD56;NCAM;MSK39;NCAM1;neural cell adhesion molecule 1;NCAM-1;N-CAM-1;OTTHUMP00000235666;neural cell adhesion molecule, NCAM;antigen recognized by Monoclonal 5.1H11;ANTI-CD56 Mouse;ANTI-CD56;NATURAL KILLER CELL;ANTI-CD56, NCAM;ANTI-CD56/NCAM-1 Mouse MAb;ANTI-CD56, NATURAL KILLER CELL;ANTI-SCLC;ANTI-NKH1;CD56;NCAM1;NCAM;MSK39
Recombinant Proteins
- Human
- Mouse
- Chicken
- Rat
- Insect Cells
- Mammalian Cells
- HEK293
- Wheat Germ
- Human
- Human Cells
- E.coli
- His
- Non
- T7
- Fc
- Avi
- GST
- DDK
- Myc
- Flag
Involved Pathway
NCAM1 involved in several pathways and played different roles in them. We selected most pathways NCAM1 participated on our site, such as Cell adhesion molecules (CAMs),Prion diseases, which may be useful for your reference. Also, other proteins which involved in the same pathway with NCAM1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Prion diseases | PRKACA,FYN,HSPA1A,C1QC,C7,PRNP,CASP12,MAPK3,PRKACG,LAMC1 |
| Cell adhesion molecules (CAMs) | CLDN4,NRCAM,CLDN15,NLGN2B,HLA-G,Siglec1,NLGN3A,SPN,HLA-B,ITGAL |
Protein Function
NCAM1 has several biochemical functions, for example, identical protein binding,virus receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by NCAM1 itself. We selected most functions NCAM1 had, and list some proteins which have the same functions with NCAM1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| virus receptor activity | HTR2A,NPC1,TYRO3,PVRL1,CD4,CXADR,ITGAV,ITGB5,HSPA1B,HLA-DRB1 |
| identical protein binding | RUNX1T1,PTEN,TK1,CBY1,CBX3,IMPA1,IIGP1,CLDN6,SHANK3,APOH |
Interacting Protein
NCAM1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NCAM1 here. Most of them are supplied by our site. Hope this information will be useful for your research of NCAM1.
UCHL1;ATXN1;RHEB;q74yh2_yerpe;q7cgx2_yerpe;flhB
Resources
Research Area
- Natural Killer Cells (NK Cells) Markers
- Myogenesis Markers
- Immunoglobulin Superfamily CAMs
- Synaptic Adhesion Molecules
- Synaptic Proteins
- Mesenchymal Stem Cell Markers
- Conventional/Classical Dendritic Cells
- Natural Killer T (NKT) Cells
- Lymphoid Lineage Markers
- Mesodermal Lineage Markers
- Myogenic Precursor Markers
- Skeletal Muscle Markers
- GDNF Family Receptors
- Neural Progenitor Cell Markers
- Glioma Biomarkers
- CAR-T Cell Therapy Targets
Related Services
Related Products
References
- Yu, XY; Liu, SP; et al. MicroRNA-572 Improves Early Post-Operative Cognitive Dysfunction by Down-Regulating Neural Cell Adhesion Molecule 1. PLOS ONE 10:-(2015).
- Solich, J; Kolasa, M; et al. Effect of desipramine on gene expression in the mouse frontal cortex - Microarray study. PHARMACOLOGICAL REPORTS 67:345-348(2015).
