oprm1
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  • Official Full Name
  • opioid receptor, mu 1
  • Background
  • The κ-opioid receptor (KOR) is a protein that in humans is encoded by the OPRK1 gene. The κ-opioid receptor is one of five related receptors that bind opium-like compounds in the brain and are responsible for mediating the effects of these compounds. These effects include altering the perception of pain, consciousness, motor control, and mood.
  • Synonyms
  • OPRK1; K-OR-1; Kappa type opioid receptor; Kappa-type opioid receptor; KOR 1; KOR; KOR-1; Opiate receptor kappa 1; OPRK 1; OPRK; OPRK_HUMAN; Oprk2; R21; opioid receptor, kappa 1; OTTHUMP00000226313; Opioid Receptor, kappa; OTTHUMP00000226316; kappa opioid receptor; Opiate receptor, kappa-1
Cat.#:OPRM1-295HTag:Myc|DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human OPRM1 Protein, MYC/DDK-tagged
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Cat.#:OPRM1-12176MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse OPRM1 Protein
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Cat.#:OPRM1-4196RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat OPRM1 Protein
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Cat.#:OPRM1-767CTag:His
Source (Host):Mammalian CellsSpecies:Cynomolgus Monkey
Product nameRecombinant Cynomolgus OPRM1 Protein, His-tagged
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Cat.#:OPRM1-3170RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey OPRM1 Protein, His-tagged
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Cat.#:OPRM1-9229ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish OPRM1
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Cat.#:Kit-1078Tag:N/A
Source (Host):Species:
Product nameOxalate Oxidase Activity Assay Kit (Fluorometric)
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Cat.#:Kit-1009Tag:N/A
Source (Host):Species:
Product nameCell Migration/Chemotaxis Assay Kit (24-well, 8 μm)
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Cat.#:Kit-1010Tag:N/A
Source (Host):Species:
Product nameCell Migration/Chemotaxis Assay Kit (24-well, 5 μm)
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Cat.#:Kit-1458Tag:N/A
Source (Host):Species:
Product namecAMP OPRM1 CHO-K1 GPCR Assay Kit
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Cat.#:Kit-1459Tag:N/A
Source (Host):Species:
Product nameOPRM1 CHO K1 β-Arrestin GPCR Assay Kit
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Cat.#:Kit-1460Tag:N/A
Source (Host):Species:
Product nameOPRM1 U2OS β-Arrestin GPCR Assay Kit
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Cat.#:Kit-1461Tag:N/A
Source (Host):Species:
Product nameOPRM1 U2OS β-Arrestin-1 GPCR Assay Kit
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Cat.#:Kit-1462Tag:N/A
Source (Host):Species:
Product nameOPRM1 Total GPCR Internalization Assay Kit
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Cat.#:Kit-0885Tag:N/A
Source (Host):Species:
Product nameMaxi Protein Expression Kit
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Cat.#:Kit-0886Tag:N/A
Source (Host):Species:
Product nameProtein Synthesis Kit
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Involved Pathway

OPRM1 involved in several pathways and played different roles in them. We selected most pathways OPRM1 participated on our site, such as Neuroactive ligand-receptor interaction, Estrogen signaling pathway, Morphine addiction, which may be useful for your reference. Also, other proteins which involved in the same pathway with OPRM1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Neuroactive ligand-receptor interaction
S1PR2; CHRNB3A; GABRB2; GRIN2BB; CNR1; NPY1R; OPRD1; CNR2; TAAR8A; OXTR
Estrogen signaling pathway
HSP90AB1; NRAS; HSP90B1; HSPA1A; GRB2; ITPR3; KCNJ5; ESR2; CALM1; MMP9
Morphine addiction
GNAI3; GABRE; GNB1; GABRA3; PDE11A; PRKCA; GABRA4; GNG12; GNGT2; GNG2

Protein Function

OPRM1 has several biochemical functions, for example, G-protein alpha-subunit binding, G-protein beta-subunit binding, G-protein coupled receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by OPRM1 itself. We selected most functions OPRM1 had, and list some proteins which have the same functions with OPRM1. You can find most of the proteins on our site.
Function
Related Protein
Function G-protein alpha-subunit binding
Related Protein RGS4; RIC8; ARHGEF11; OPRM1; DRD1A; ADRB2; HTR2B; RIC8A; PPP5C; LPAR3
Function G-protein beta-subunit binding
Related Protein RGS7; CCT5; GNG2; RGS9; OPRM1; GNG13; RGS11; F2R; F2RL1; RASD2
Function G-protein coupled receptor activity
Related Protein TAAR10C; PTGER4A; OLFCG5; GRM2A; CXCR3.2; OLFR688; OPN1MW2; GPR132; LPHN1; SMO
Function beta-endorphin receptor activity
Related Protein OPRM1
Function morphine receptor activity
Related Protein OPRM1
Function neuropeptide binding
Related Protein GPR149; SSTR1; MC4R; NPBWR1; OPRL1; ADCYAP1R1; GALR1; SSTR4; GPR1; OPRM1
Function protein binding
Related Protein BRAP; SYVN1; COMMD1; SRSF10; PRSS3; LRP4; RHEB; DPCD; CDKN2D; SLC1A5
Function voltage-gated calcium channel activity
Related Protein RYR1; TPC3; CACNG1A; CALHM1; CACNB2B; CACNG6; CATSPER3; CACNG1; TMC1; PKD2

Interacting Protein

OPRM1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with OPRM1 here. Most of them are supplied by our site. Hope this information will be useful for your research of OPRM1.
WLS; RANBP9; FLNA