PDGFRA

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PDGFRA

Official Full Name platelet-derived growth factor receptor, alpha polypeptide
Background This gene encodes a member of a subfamily of non-clustered, diverged, antennapedia-like homeobox-containing genes. The encoded protein may play a role in the molecular signaling network regulating somite development. Alternatively spliced transcript variants encoding different isoforms have been described.
Synonyms PDGFRA; platelet-derived growth factor receptor, alpha polypeptide; platelet-derived growth factor receptor alpha; CD140a; PDGFR2; PDGFR-alpha; PDGF-R-alpha; CD140a antigen; PDGFRA/BCR fusion; CD140 antigen-like family member A; platelet-derived growth factor receptor 2; alpha-type platelet-derived growth factor receptor; rearranged-in-hypereosinophilia-platelet derived growth factor receptor alpha fusion protein; CD140A; PDGFR-2; RHEPDGFRA; MGC74795
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Human
    • Human Cell
    • Insect Cell
    • Mammalian Cell
    • NS0
    • NSO
    • Sf9 Insect Cell
    • Tag :
    • DDK
    • His
    • Fc
    • GST
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Mouse Pdgfra-1774M Recombinant Mouse Pdgfra Protein, Fc-tagged NS0 Fc
    Human PDGFRA-2050H Recombinant Human PDGFRA Protein, Fc/His-tagged HEK293 Fc/His
    Human PDGFRA-001HCL Recombinant Human PDGFRA cell lysate Insect Cell N/A
    Human PDGFRA-1147H Recombinant Human Platelet-Derived Growth Factor Receptor, Alpha Polypeptide, His-tagged Human His
    Human PDGFRA-1287H Recombinant Human Platelet-Derived Growth Factor Receptor, Alpha Polypeptide, GST-tagged Insect Cell GST
    Human PDGFRA-147H Recombinant Human PDGFRA Protein, DDK/HIS-tagged HEK293 DDK/His
    Human PDGFRA-1576H Recombinant Human Platelet-Derived Growth Factor Receptor, Alpha Polypeptide Sf9 Insect Cell N/A
    Human PDGFRA-1612H Recombinant Human PDGFRA, GST-tagged E.coli GST
    Human PDGFRA-1676H Recombinant Human PDGFRA NSO N/A
    Human PDGFRA-188H Recombinant Human PDGFRA Protein, His-tagged E.coli His
    Human PDGFRA-2657HCL Recombinant Human PDGFRA cell lysate Human Cell N/A
    Human PDGFRA-29161TH Recombinant Human PDGFRA protein, GST-tagged Insect Cell GST
    Human PDGFRA-30830TH Recombinant Human PDGFRA N/A
    Human PDGFRA-3181H Recombinant Human PDGFRA protein, His-tagged HEK293 His
    Human PDGFRA-3560H Recombinant Human PDGFRA, His-tagged E.coli His
    Human PDGFRA-384H Recombinant Human PDGFRA, GST-tagged, Active Sf9 Insect Cell GST
    Human PDGFRA-662H Recombinant Human PDGFRA, Fc-tagged, Biotinylated Human Cell Fc
    Human PDGFRA-7290H Recombinant Human PDGFRA, His & GST tagged Insect Cell His/GST
    Human PDGFRA-824H Recombinant Human PDGFRA, Fc tagged Human Cell Fc
    Human PDGFRA-825H Recombinant Human PDGFRA, None tagged Human Cell N/A
    Mouse PDGFRA-12570M Recombinant Mouse PDGFRA Protein Mammalian Cell His
    Mouse Pdgfra-385M Recombinant Mouse Pdgfra, GST-tagged, Active Sf9 Insect Cell GST
    Rat Pdgfra-51R Recombinant Rat Pdgfra, Fc tagged Human Cell His
    Rat Pdgfra-52R Recombinant Rat Pdgfra, His tagged Human Cell His
    Rat PDGFRA-824RCL Recombinant Rat PDGFRA cell lysate Human Cell N/A
    Chicken PDGFRA-6314C Recombinant Chicken PDGFRA Mammalian Cell His
    Zebrafish PDGFRA-9027Z Recombinant Zebrafish PDGFRA Mammalian Cell His
    Kit-1615 PDGFRa Functional Assay Kit N/A
    Kit-1616 U2OS PDGFRa Bioassay Kit N/A

    PDGFRA involved in several pathways and played different roles in them. We selected most pathways PDGFRA participated on our site, such as content, which may be useful for your reference. Also, other proteins which involved in the same pathway with PDGFRA were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    MAPK signaling pathway ELK1; PPP3R1B; NTF4; PDGFAA; FOS; CACNB2A; MAP3K11; DUSP8A; KCNA3; PPP3R1
    Ras signaling pathway PRKACA; MRAS; CALML3; ETS2; ZAP70; Kitl; IGF1R; SHC3; INS1; GNG13
    Rap signaling pathway PIK3CG; ITGA2B; PARD6B; FGF6; FPR1; BRAF; RHOA; PIK3R5; CALM2; FLT1
    Calcium signaling pathway TACR3L; TACR3; TNNC2; ADRa1A; P2RX3A; ERBB3; P2RX1; EDNRA; CYSLTR2; PHKG2
    Cytokine-cytokine receptor interaction IFNB1; BMPR1B; Fasl; FASLG; CCL19B; EDAR; IL11RA; RELT; TNF; CCL25
    Phospholipase D signaling pathway GRM8; PIK3R3; SOS1; INS; GRB2; PPAP2C; PTPN11; DGKE; LPAR4; TSC2
    Endocytosis GRK5; SNF8; ARFGAP1; HLA-C; PDCD6IP; ARPC2; HLA-E; IST1; FOLR1; RAB7A
    PIK-Akt signaling pathway TCL1B4; LAMB3; IRS1; BCL2L1; IL6R; FLT1; EPOR; TLR4; PPP2R5D; AKT2
    Focal adhesion CDC42L2; PIK3CA; THBS4; PTENA; FLNC; ROCK2B; CAPN2L; TNW; ITGB7; MAPK8
    Gap junction GNAIA; PDGFC; PDGFAB; TUBB2B; CX35B; PRKACBA; MAP2K2B; SRC; Pdgfa&Pdgfb; MAP3K2
    Regulation of actin cytoskeleton CHRM2A; HRASA; ARPC4L; VAV3; MAP2K2A; BDKRB2; MYLPF; ACTN2B; MYL2B; CHRM5A
    HTLV-I infection MSX2; TP53INP1; IL6; LTA; SFPI1; TBP; DVL2; TGFBR1; ELK1; PIK3R2
    Pathways in cancer NFKB2; WNT9B; EGLN3; FH1; PTGS2; IGF1R; KRAS; NKX3-1; CCND1; PRKACG
    MicroRNAs in cancer PDGFRA; PDGFA; PDGFB; RECK; NOTCH4; CD44; ABL1; PLCG2; TPM1; APC2
    Glioma PIK3CA; CAMK2B; SHC3; MAPK1; SHC4; GRB2; ARAF; MAP2K2; PDGFB; CCND1
    Prostate cancer IGF1R; INS; PDGFD; INS1; FGFR2; NOXA1; PIK3CD; INSRR; MAP4K1; ATF4
    Melanoma FGF20; FGF1; MDM2; PIK3R2; RAF1; HGF; FGF14; TP53; FGF17; PDGFRB
    Central carbon metabolism in cancer NTRK3; GLS; MTOR; FGFR2; PTEN; PIK3R1; SIRT3; AKT1; HK3; MAPK1
    Choline metabolism in cancer PLA2G4F; TSC1; RPS6KB1; RAC1; PIP5K1B; RALGDS; DGKQ; SLC5A7; PIK3R2; NRAS

    PDGFRA has several biochemical functions, for example, Content. Some of the functions are cooperated with other proteins, some of the functions could acted by PDGFRA itself. We selected most functions PDGFRA had, and list some proteins which have the same functions with PDGFRA. You can find most of the proteins on our site.

    Function Related Protein
    ATP binding DDX43; RECQL4; CDK14; KLHL8; HSP90AA1; ACSM5; ETNK1; AMHR2; FLAD1; KIF18B
    platelet-derived growth factor alpha-receptor activity PDGFRA
    platelet-derived growth factor binding COL3A1; COL1A2; PDGFRB; Pdgfa&Pdgfb; COL2A1; PDGFRA; COL4A1; COL1A1; COL5A1; PDGFB
    platelet-derived growth factor receptor binding LYN; PTEN; PDGFA; Pdgfa&Pdgfb; VEGFA; FIGF; IL1R1; PDGFB; ITGB3; PDGFAB
    protein binding MAPKAPK5; MSTN; IP6K2; CTNNB2; PBX4; PPP1R8; MCCC1; ID1; NUF2; C20orf195
    protein homodimerization activity COMMD1; SUMF1; CD226; SP1; SLK; TGFB2; RELA; CD247; GRHPR; ATPIF1
    protein kinase activity MAP2K4B; NPR2; NRBP1; MYO3A; PDPK1B; TGFBR1; VRK1; DCLK3; NAT1; RPS6KB1B
    transmembrane receptor protein tyrosine kinase activity RYK; FGFR1B; EPHB3A; NPTN; TRIM27; MUSK; ERBB3B; NTRK3; EPHB4A; NTRK3A
    vascular endothelial growth factor binding PDGFRB; PDGFRA; KDR; NRP1
    vascular endothelial growth factor-activated receptor activity NRP2B; NRP2; KDR; NRP2A; PDGFRA; FLT1; NRP1A; FLT4; FLT3; NRP1

    PDGFRA has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PDGFRA here. Most of them are supplied by our site. Hope this information will be useful for your research of PDGFRA.

    PDGFB; CRK; PDGFA

    Yi, JH; Park, BB; et al. Retrospective analysis of extra-gastrointestinal stromal tumors. WORLD JOURNAL OF GASTROENTEROLOGY 21:1845-1850(2015).
    Albuquerque, A; Rios, E; et al. Evaluation of clinico-pathological features and Helicobacter pylori infection in gastric inflammatory fibroid polyps. VIRCHOWS ARCHIV 465:643-647(2014).

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