Recombinant Active Human PDGFR alpha (E675G Y676C) Mutant Protein, GST-tagged
Cat.No. : | PDGFRA-38H |
Product Overview : | Recombinant human PDGFRα (E675G Y676C) (550-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers. |
Source : | Insect cell |
Species : | Human |
Tag : | GST |
Molecular Mass : | Approx 95 kDa |
Purity : | > 90% |
Stability : | One year at -70 centigrade from data of shipment. |
Storage : | Store product at –70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
Concentration : | 0.05 μg/μL |
Storage Buffer : | Recombinant protein stored in 50 mM sodium phosphate, pH 7.0, 300 mM NaCl, 150 mM imidazole, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol. |
Shipping : | Dry ice |
Gene Name : | PDGFRA platelet derived growth factor receptor alpha [ Homo sapiens (human) ] |
Official Symbol : | PDGFRA |
Synonyms : | PDGFRA; platelet derived growth factor receptor alpha; CD140A; PDGFR2; PDGFR-2; platelet-derived growth factor receptor alpha; CD140 antigen-like family member A; CD140a antigen; PDGF-R-alpha; alpha-type platelet-derived growth factor receptor; platelet-derived growth factor receptor 2; platelet-derived growth factor receptor, alpha polypeptide; EC 2.7.10.1 |
Gene ID : | 5156 |
mRNA Refseq : | NM_006206 |
Protein Refseq : | NP_006197 |
MIM : | 173490 |
UniProt ID : | P16234 |
Products Types
◆ Recombinant Protein | ||
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PDGFRA-2050H | Recombinant Human PDGFRA Protein, Fc/His-tagged | +Inquiry |
PDGFRA-188H | Recombinant Human PDGFRA Protein, His-tagged | +Inquiry |
Pdgfra-1774M | Active Recombinant Mouse Pdgfra Protein, Fc-tagged | +Inquiry |
PDGFRA-2664H | Recombinant Human PDGFRA protein(961-1040 aa), C-His-tagged | +Inquiry |
◆ Lysates | ||
PDGFRA-824RCL | Recombinant Rat PDGFRA cell lysate | +Inquiry |
PDGFRA-001HCL | Recombinant Human PDGFRA cell lysate | +Inquiry |
PDGFRA-2657HCL | Recombinant Human PDGFRA cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-1615 | PDGFRa Functional Assay Kit | +Inquiry |
Kit-1616 | U2OS PDGFRa Bioassay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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