Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at BIO-Europe Spring|March 18–20, 2024|Booth #34

PRKAB1

  • Official Full Name

    protein kinase, AMP-activated, beta 1 non-catalytic subunit

  • Overview

    The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. The myristoylation and phosphorylation of this subunit have been shown to affect the enzyme activity and cellular localization of AMPK. This subunit may also serve as an adaptor molecule mediating the association of the AMPK complex. [provided by RefSeq, Jul 2008]
  • Synonyms

    PRKAB1; protein kinase, AMP-activated, beta 1 non-catalytic subunit; AMPK; HAMPKb; 5-AMP-activated protein kinase subunit beta-1; AMPKb; AMPK beta 1; AMPK beta -1 chain; AMPK subunit beta-1; AMP-activated protein kinase beta subunit; 5-AMP-activated protein kinase beta-1 subunit; protein kinase, AMP-activated, noncatalytic, beta-1;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • E.coli
  • HEK293
  • HEK293T
  • Insect Cell
  • Mammalian Cell
  • Sf9 Insect Cell
  • GST
  • His
  • His (Fc)
  • Avi
  • His|GST
  • His|MBP
  • Myc
  • DDK
  • N/A
  • N
  • No tag
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human PRKAB1-4869H Recombinant Human Protein Kinase, AMP-Activated, Beta 1 Non-Catalytic Subunit, His-tagged Sf9 Insect Cell His
Human PRKAB1-370H Recombinant Human PRKAB1 protein, His/MBP-tagged E.coli His/MBP 118-226 aa
Human PRKAB1-4866H Recombinant Human Protein Kinase, AMP-Activated, Beta 1 Non-Catalytic Subunit, His-tagged Sf9 Insect Cell His
Human PRKAB1-1945H Recombinant Human PRKAB1, His-tagged E.coli His 1-270aa
Human PRKAB1-4870H Recombinant Human Protein Kinase, AMP-Activated, Beta 1 Non-Catalytic Subunit, His-tagged Sf9 Insect Cell His
Human PRKAB1-4865H Recombinant Human Protein Kinase, AMP-Activated, Beta 1 Non-Catalytic Subunit, His-tagged Sf9 Insect Cell His
Human PRKAB1-347H Recombinant Human protein kinase, AMP-activated, beta 1 non-catalytic subunit, His-tagged E.coli His
Human PRKAB1-1785H Recombinant Human PRKAB1 protein, His & GST-tagged E.coli His/GST Arg13~Leu242 (Accession # Q9Y478)
Human PRKAB1-4868H Recombinant Human Protein Kinase, AMP-Activated, Beta 1 Non-Catalytic Subunit, His-tagged Sf9 Insect Cell His
Human PRKAB1-4867H Recombinant Human Protein Kinase, AMP-Activated, Beta 1 Non-Catalytic Subunit, His-tagged Sf9 Insect Cell His
Human AMPK-411HCL Recombinant Human AMPK cell lysate Insect Cell N/A
Human AMPK-410HCL Recombinant Human AMPK cell lysate Insect Cell N/A
Human AMPK-416HCL Recombinant Human AMPK cell lysate Insect Cell N/A
Human AMPK-412HCL Recombinant Human AMPK cell lysate Insect Cell N/A
Human PRKAB1-2869HCL Recombinant Human PRKAB1 293 Cell Lysate HEK293 N/A
Human PRKAB1-3249H Recombinant Human PRKAB1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human PRKAB1-0735H Recombinant Human PRKAB1 Protein (G2-I270), Tag Free Insect Cell No tag G2-I270
Human PRKAB1-3081H Recombinant Human PRKAB1 protein, His-tagged E.coli His 1 - 70 aa
Human PRKAB1-0736H Recombinant Human PRKAB1 Protein (G2-I270), GST tagged Insect Cell GST G2-I270
Human PRKAB1-5984H Recombinant Human PRKAB1 Protein (Arg13-Leu242), N-GST tagged E.coli N-GST Arg13-Leu242
Mouse Prkab1-4932M Recombinant Mouse Prkab1 protein, His-tagged E.coli His 2-270aa
Mouse Prkab1-5110M Recombinant Mouse Prkab1 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rat PRKAB1-4670R Recombinant Rat PRKAB1 Protein Mammalian Cell His
Rat PRKAB1-4329R Recombinant Rat PRKAB1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat PRKAB1-4329R-B Recombinant Rat PRKAB1 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque PRKAB1-3601R Recombinant Rhesus monkey PRKAB1 Protein, His-tagged Mammalian Cell His
Rhesus Macaque PRKAB1-3419R Recombinant Rhesus Macaque PRKAB1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque PRKAB1-3419R-B Recombinant Rhesus Macaque PRKAB1 Protein Pre-coupled Magnetic Beads HEK293
Chicken PRKAB1-3403C Recombinant Chicken PRKAB1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • PRKAB1 Related Articles
  • PRKAB1 Related Research Area
  • PRKAB1 Related Signal Pathway

PRKAB1 involved in several pathways and played different roles in them. We selected most pathways PRKAB1 participated on our site, such as FoxO signaling pathway, AMPK signaling pathway, Circadian rhythm, which may be useful for your reference. Also, other proteins which involved in the same pathway with PRKAB1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
FoxO signaling pathwayRAG2;USP7;PRKAG1;SGK2A;PRKAB2;RAF1B;CCNB1;MAPK3;GABARAPA
AMPK signaling pathwayACACA;INS2;MTOR;FOXO1;FASN;PPP2R2B;PRKAB2;LEPR;RHEB
Circadian rhythmPRKAB2;CUL1;BHLHE40;RBX1;RORA;CSNK1E;PRKAB1;BTRC;FBXL3
Insulin signaling pathwayFBP1;HK1;PIK3CA;HK3;PTPRFB;RPS6KB1;MAPK10;HKDC1;PIK3R1
Adipocytokine signaling pathwayNFKB1;SLC2A1;AGRP;IRS1;PCK2;MAPK8;JAK2A;TNF;STAT3
Oxytocin signaling pathwayMAP2K1;GNAI2;RGS2;CACNA2D1;CAMK1G;ACTG1;CACNB3;CACNG8;MEF2C
Insulin resistancePIK3R3A;PYGM;RPS6KB2;PPP1R3CB;GFPT1;MAPK8;MLXIPL;PYGB;PPP1R3D
Non-alcoholic fatty liver disease (NAFLD)TNFRSF1A;NDUFB2;NDUFB11;NDUFB7;UQCRC1;GSK3B;NDUFV3;NDUFC2;NDUFA10
Hypertrophic cardiomyopathy (HCM)CACNB2;SLC8A1;TNF;ITGA1;ACTG1;ITGB3;CACNG1;CACNG6;ITGA2B

PRKAB1 has several biochemical functions, for example, AMP-activated protein kinase activity, protein binding, protein kinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PRKAB1 itself. We selected most functions PRKAB1 had, and list some proteins which have the same functions with PRKAB1. You can find most of the proteins on our site.

Function Related Protein
AMP-activated protein kinase activityALPK2;PRKAB1;PRKAG3;PRKAG2;PRKAA1;PRKAA2
protein bindingALDH3A1;C9orf86;ANKS1A;HACE1;SDCCAG3;SH3YL1;GSN;SP100;EPHB6
protein kinase activityKDRL;FGFR1A;PKN2;TRIO;MKNK2B;PDK1;MAP2K4A;NRBP2;SRPK1B
protein kinase bindingADRA2A;RACGAP1;CD24;ADCY6;TTN;STK11IP;CNPPD1;YWHAZ;AGAP2

PRKAB1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PRKAB1 here. Most of them are supplied by our site. Hope this information will be useful for your research of PRKAB1.

PRKAA1; PRKAG1; PRKAB2; CBR1; Cidea; GRB2

Brett, KE; Ferraro, ZM; et al. Prenatal physical activity and diet composition affect the expression of nutrient transporters and mTOR signaling molecules in the human placenta. PLACENTA 36:204-212(2015).
Banerjee, S; Zagorska, A; et al. Interplay between Polo kinase, LKB1-activated NUAK1 kinase, PP1 beta(MYPT1) phosphatase complex and the SCF beta TrCP E3 ubiquitin ligase. BIOCHEMICAL JOURNAL 461:233-245(2014).
  • Q&As
  • Reviews

Q&As (0)

Ask a question

Customer Reviews (0)

Write a review

Ask a Question for All PRKAB1 Products

Required fields are marked with *

My Review for All PRKAB1 Products

Required fields are marked with *

logo

FOLLOW US

Terms and Conditions        Privacy Policy

Copyright © 2024 Creative BioMart. All Rights Reserved.

Contact Us

  • /

Stay Updated on the Latest Bioscience Trends