ren
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  • Official Full Name
  • renin
  • Background
  • Prorenin is a glycosylated aspartic protease that consists of 2?homologouslobes and is the precursor of renin. Renin activates the renin-angiotensinsystem by cleaving angiotensinogen, produced by the liver, to yield angiotensinI, which is further converted into angiotensin II by ACE, theangiotensin-converting enzyme primarily within the capillaries of the lungs. Ithas been reported that the levels of circulating prorenin (but not renin) areincreased in diabetic subjects.
  • Synonyms
  • Prorenin; REN; renin; angiotensinogenase; renin precursor, renal; angiotensin-forming enzyme; HNFJ2; FLJ10761
Cat.#:REN-5473HTag:N/A
Source (Host):Human Embryonic Kidney cellsSpecies:Human
Product nameRecombinant Human Renin
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Cat.#:REN-803HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human REN Protein, MYC/DDK-tagged
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Cat.#:REN-5472DTag:His
Source (Host):Human Embryonic Kidney CellsSpecies:Dog
Product nameRecombinant Dog Renin, His-tagged
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Cat.#:REN-700DTag:His
Source (Host):HEK293Species:Dog
Product nameRecombinant Dog Renin, His-tagged
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Cat.#:REN-052HTag:His
Source (Host):HEK293 cellsSpecies:Human
Product nameRecombinant Human REN Protein, His-tagged
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Cat.#:REN-1111HTag:His
Source (Host):NSO CellsSpecies:Human
Product nameRecombinant Human REN Protein, His-tagged
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Cat.#:REN-223HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human renin, His-tagged
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Cat.#:REN-2253HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human REN, His-tagged
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Cat.#:REN-31180THTag:His
Source (Host):Species:Human
Product nameRecombinant Human REN, His-tagged
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Cat.#:REN-317HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human REN, His tagged
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Cat.#:REN-73HTag:
Source (Host):YeastSpecies:Human
Product nameRecombinant Human REN
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Cat.#:Ren-16RTag:His
Source (Host):HEK293Species:Rat
Product nameRecombinant Rat Ren, His-tagged
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Cat.#:Ren-2454RTag:His
Source (Host):HEK293Species:Rat
Product nameRecombinant Rat Renin, His-tagged
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Cat.#:REN-4994RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat REN Protein
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Cat.#:Ren-695RTag:His
Source (Host):HEK293Species:Rat
Product nameRecombinant Rat Ren protein, His-tagged
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Cat.#:Ren-7887RTag:His
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Ren protein, His-tagged
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Cat.#:Ren-7888RTag:His
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Ren protein, His-tagged
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Cat.#:REN-3848RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey REN Protein, His-tagged
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Cat.#:REN-2456DTag:His
Source (Host):HEK293Species:Dog
Product nameRecombinant Dog Renin, His-tagged
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Cat.#:REN-12121ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish REN
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Cat.#:REN -16HTag:His
Source (Host):Species:Human
Product nameRecombinant Human Prorenin, His-tagged
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Cat.#:REN-245HTag:
Source (Host):Human KidneySpecies:Human
Product nameNative Human Renin
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Cat.#:REN-388HTag:N/A
Source (Host):Human KidneySpecies:Human
Product nameNative Human Renin Antigen
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Cat.#:Ren -72RTag:His
Source (Host):Species:Rat
Product nameRecombinant Rat Prorenin, His tag
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Cat.#:REN-2862HCLTag:
Source (Host):HEK293Species:Human
Product nameRecombinant Human REN cell lysate
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Cat.#:REN-50HTag:
Source (Host):Species:Human
Product nameHuman Renin Reference standard
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Cat.#:REN-99HTag:
Source (Host):Species:Human
Product nameHuman Renin(rec DNA) Reference standard
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Cat.#:REN-48PTag:
Source (Host):Species:Pig
Product namePorcine Renin Reference standard
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Involved Pathway

REN involved in several pathways and played different roles in them. We selected most pathways REN participated on our site, such as Renin-angiotensin system, Renin secretion, which may be useful for your reference. Also, other proteins which involved in the same pathway with REN were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Renin-angiotensin system
MAS1; AGTR1A; KLK1B24; ANPEP; AGTR1B; KLK1B22; ATP6AP2; ACE; KLK1B8; KLK1B3
Renin secretion
CALM4; LOC100328615; PLCB2; PTGER2; CLCA4; PLCB1; ACE; ITPR3; CALML5; AQP1

Protein Function

REN has several biochemical functions, for example, aspartic-type endopeptidase activity, insulin-like growth factor receptor binding, peptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by REN itself. We selected most functions REN had, and list some proteins which have the same functions with REN. You can find most of the proteins on our site.
Function
Related Protein
Function aspartic-type endopeptidase activity
Related Protein PGA5; REN2; Ren1; CTSD; CNTNAP5A; SPPL3; PSEN1; PGA4; PSEN2; PGA
Function insulin-like growth factor receptor binding
Related Protein IRS1; IGF2; INSR; GNAS; SHC1; SOCS1; REN; Ren1; YWHAG; IGF1
Function peptidase activity
Related Protein USP25; TMPRSS11D; PM20D1; USP43A; CAPN2A; STAMBPA; KLK1B5; ELA3L; USP2A; TMPRSS4A
Function receptor binding
Related Protein BAAT; HCK; ABL1; FGF11A; FGF8A; JAK2; HAND2; EHHADH; FGF8B; CCL13

Interacting Protein

REN has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with REN here. Most of them are supplied by our site. Hope this information will be useful for your research of REN.
KCTD15

REN Related Articles

Pimentel, DC; El Abd, O; et al. Anti-Tumor Necrosis Factor Antagonists in the Treatment of Low Back Pain and Radiculopathy: A Systematic Review and Meta-analysis. PAIN PHYSICIAN 17:E27-E44(2014).
Volta, V; Ranzato, E; et al. Preclinical Demonstration of Synergistic Active Nutrients/Drug (AND) Combination as a Potential Treatment for Malignant Pleural Mesothelioma. PLOS ONE 8:-(2013).