REN Protein, renin


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Official Full Name renin
Background Prorenin is a glycosylated aspartic protease that consists of 2?homologouslobes and is the precursor of renin. Renin activates the renin-angiotensinsystem by cleaving angiotensinogen, produced by the liver, to yield angiotensinI, which is further converted into angiotensin II by ACE, theangiotensin-converting enzyme primarily within the capillaries of the lungs. Ithas been reported that the levels of circulating prorenin (but not renin) areincreased in diabetic subjects.
Synonyms Prorenin; REN; renin; angiotensinogenase; renin precursor, renal; angiotensin-forming enzyme; HNFJ2; FLJ10761
    • Species :
    • Dog
    • Human
    • Pig
    • Rat
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Human Cell
    • Human Kidney
    • Mammalian Cell
    • NS0
    • Yeast
    • Tag :
    • His
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human REN -16H Recombinant Human Prorenin, His-tagged HEK293 His
    Human REN-052H Recombinant Human REN protein, His-tagged HEK293 His
    Human REN-1111H Recombinant Human REN Protein, His-tagged NS0 His
    Human REN-223H Recombinant Human renin, His-tagged E.coli His
    Human REN-2253H Recombinant Human REN, His-tagged E.coli His
    Human REN-245H Native Human Renin Human Kidney N/A
    Human REN-2862HCL Recombinant Human REN cell lysate Human Cell N/A
    Human REN-31180TH Recombinant Human REN, His-tagged His
    Human REN-317H Recombinant Human REN, His tagged Human Cell His
    Human REN-388H Native Human Renin Antigen Human Kidney N/A
    Human REN-50H Human Renin Reference standard N/A
    Human REN-5473H Recombinant Human Renin HEK293 N/A
    Human REN-73H Recombinant Human REN Yeast N/A
    Human REN-803H Recombinant Human REN Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human REN-99H Human Renin(rec DNA) Reference standard N/A
    Rat Ren -72R Recombinant Rat Prorenin, His tag HEK293 His
    Rat Ren-16R Recombinant Rat Ren, His-tagged HEK293 His
    Rat Ren-2454R Recombinant Rat Renin, His-tagged HEK293 His
    Rat REN-4994R Recombinant Rat REN Protein Mammalian Cell His
    Rat Ren-695R Recombinant Rat Ren protein, His-tagged HEK293 His
    Rat Ren-7887R Recombinant Rat Ren protein, His-tagged E.coli His
    Rat Ren-7888R Recombinant Rat Ren protein, His-tagged E.coli His
    Rhesus Macaque REN-3848R Recombinant Rhesus monkey REN Protein, His-tagged Mammalian Cell His
    Dog REN-2456D Recombinant Dog Renin, His-tagged HEK293 His
    Dog REN-5472D Recombinant Dog Renin, His-tagged HEK293 His
    Dog REN-700D Recombinant Dog Renin, His-tagged HEK293 His
    Zebrafish REN-12121Z Recombinant Zebrafish REN Mammalian Cell His
    Pig REN-48P Porcine Renin Reference standard N/A

    REN involved in several pathways and played different roles in them. We selected most pathways REN participated on our site, such as Renin-angiotensin system, Renin secretion, which may be useful for your reference. Also, other proteins which involved in the same pathway with REN were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Renin-angiotensin system KLK1; KLK1B1; KLK1B5; AGTR1A; KLK1B11; KLK2; KLK1B8; PREP; AGTR1B; ATP6AP2
    Renin secretion PPP3CB; CALML5; CLCA4; CLCA2; GUCY1B3; PPP3R1; PRKACG; GNAQ; Ren1; AGTR1B

    REN has several biochemical functions, for example, aspartic-type endopeptidase activity, insulin-like growth factor receptor binding, peptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by REN itself. We selected most functions REN had, and list some proteins which have the same functions with REN. You can find most of the proteins on our site.

    Function Related Protein
    aspartic-type endopeptidase activity BACE1; DDI1; SPPL2; ANK2B; BACE2; CTSD; REN2; PGA4; SPPL3; ATP6AP2
    insulin-like growth factor receptor binding INS; IGF2A; INS2; IGF3; REN; SHC1; SOCS1; PIK3R1; IGF2; GNAS
    peptidase activity DHH; KLK1B22; MMP30; TMPRSS11F; UCHL3; TMPRSS12; GZMF; MMP1A; TMPRSS5; CTSSB.2
    receptor binding PRDX5; CD70; LRRC4B; STRAP; SSTR3; PTK2AA; ECI2; MCHR1; CCDC129; NXPH1

    REN has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with REN here. Most of them are supplied by our site. Hope this information will be useful for your research of REN.


    Pimentel, DC; El Abd, O; et al. Anti-Tumor Necrosis Factor Antagonists in the Treatment of Low Back Pain and Radiculopathy: A Systematic Review and Meta-analysis. PAIN PHYSICIAN 17:E27-E44(2014).
    Volta, V; Ranzato, E; et al. Preclinical Demonstration of Synergistic Active Nutrients/Drug (AND) Combination as a Potential Treatment for Malignant Pleural Mesothelioma. PLOS ONE 8:-(2013).

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