slc1a3
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  • Official Full Name
  • solute carrier family 1 (glial high affinity glutamate transporter), member 3
  • Background
  • This gene encodes a member of a member of a high affinity glutamate transporter family. Mutations in this gene are; associated with episodic ataxia, Type 6. Alternative splicing results in multiple transcript variants.
  • Synonyms
  • SLC1A3; solute carrier family 1 (glial high affinity glutamate transporter), member 3; excitatory amino acid transporter 1; glutamate/aspartate transporter; solute carrier family 1 member 3; solute carrier family 1, member 3; glial high affinity glutamate transporter; high-affinity neuronal glutamate transporter; sodium-dependent glutamate/aspartate transporter 1; Gmt1; Eaat1; GLAST; GLU-T; GluT-1; MGluT1; GLAST-1; AI504299; B430115D02Rik;
Cat.#:SLC1A3-26509THTag:
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human SLC1A3
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Cat.#:SLC1A3-2704HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human SLC1A3, GST-tagged
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Cat.#:SLC1A3-15254MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse SLC1A3 Protein
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Cat.#:SLC1A3-4231RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey SLC1A3 Protein, His-tagged
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Cat.#:SLC1A3-1619HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human SLC1A3 cell lysate
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Involved Pathway

SLC1A3 involved in several pathways and played different roles in them. We selected most pathways SLC1A3 participated on our site, such as Glutamatergic synapse, which may be useful for your reference. Also, other proteins which involved in the same pathway with SLC1A3 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Glutamatergic synapse
GRM2; PRKCG; SLC17A7; GRIN3B; GNG2; ITPR1; GNG5; PRKCA; PLCB1; SLC1A1

Protein Function

SLC1A3 has several biochemical functions, for example, L-glutamate transmembrane transporter activity, glutamate binding, high-affinity glutamate transmembrane transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SLC1A3 itself. We selected most functions SLC1A3 had, and list some proteins which have the same functions with SLC1A3. You can find most of the proteins on our site.
Function
Related Protein
Function L-glutamate transmembrane transporter activity
Related Protein SLC17A6A; SLC38A7; SLC25A13; SLC1A2; SLC25A12; SLC25A22; SLC1A6; SLC17A6B; SLC1A3; SLC1A7
Function glutamate binding
Related Protein GRIN1; GRIK1; GLUL; GRM7; GRIN2A; GCLC; CPS1; SLC1A1; GAD2; SLC1A3
Function high-affinity glutamate transmembrane transporter activity
Related Protein SLC1A3
Function sodium:dicarboxylate symporter activity
Related Protein SLC1A3A; SLC1A3; SLC1A4; SLC1A7; SLC1A3B; SLC1A7A; SLC1A1; SLC13A3; SLC1A2B; SLC1A2

Interacting Protein

SLC1A3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SLC1A3 here. Most of them are supplied by our site. Hope this information will be useful for your research of SLC1A3.
TNFRSF1B; ZDHHC17; ssrna_ug