Recombinant Human SLC1A3 Protein (T2-M542), 8×His-MBP, Flag tagged

• Cat.No.: SLC1A3-1215H
• Product Overview: Recombinant Human 8His-MBP-TEV-(GG)-SLC1A3(T2-M542)-Flag Protein was expressed in Insect cell.

Specification

• Description: Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate. Functions as a symporter that transports one amino acid molecule together with two or three Na(+) ions and one proton, in parallel with the counter-transport of one K(+) ion. Mediates Cl(-) flux that is not coupled to amino acid transport; this avoids the accumulation of negative charges due to aspartate and Na(+) symport. Plays a redundant role in the rapid removal of released glutamate from the synaptic cleft, which is essential for terminating the postsynaptic action of glutamate.
• Source: Insect cell
• Species: Human
• Tag: 8His-MBP,Flag
• Form: Liquid
• Protein Length: T2-M542
• Endotoxin: < 0.01 EU per μg of the protein
• Purity: 80%
• Stability: Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade.
• Storage: Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Storage Buffer: Formulation:
• Shipping: It is shipped out with blue ice.

Gene Information

• Gene Name: SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 [ Homo sapiens (human) ]
• Official Symbol: SLC1A3
• Synonyms: SLC1A3; solute carrier family 1 (glial high affinity glutamate transporter), member 3; excitatory amino acid transporter 1; EA6; EAAT1; GLAST; glutamate transporter variant EAAT1ex9skip; GLAST-1; solute carrier family 1 member 3; sodium-dependent glutamate/aspartate transporter 1; GLAST1; FLJ25094
• Gene ID: 6507
• mRNA Refseq: NM_001166695
• Protein Refseq: NP_001160167
• MIM: 600111
• UniProt ID: P43003