stx2
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  • Official Full Name
  • syntaxin 2
  • Background
  • The product of this gene belongs to the syntaxin/epimorphin family of proteins. The syntaxins are a large protein family implicated in the targeting and fusion of intracellular transport vesicles. The product of this gene regulates epithelial-mesenchymal interactions and epithelial cell morphogenesis and activation. Alternatively spliced transcript variants encoding different isoforms have been identified.
  • Synonyms
  • STX2; syntaxin 2; EPIM, epimorphin , STX2A, STX2B, STX2C; syntaxin-2; EPM; EPIM; Epimorphin; MGC51014; OTTHUMP00000238636; OTTHUMP00000238637; STX2_HUMAN; STX2A; STX2B; STX2C; Syntaxin 2C
Cat.#:STX2-2990HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human STX2 Protein, MYC/DDK-tagged
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Cat.#:STX2-4046HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human STX2 Protein, GST-tagged
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Cat.#:Stx2-411MTag:N/A
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Syntaxin 2
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Cat.#:STX2-30658THTag:
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human STX2
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Cat.#:STX2-6854HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Syntaxin 2, His-tagged
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Cat.#:STX2-5813RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat STX2 Protein
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Cat.#:STX2-3547CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken STX2
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Cat.#:STX2-1718HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human STX2 cell lysate
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Involved Pathway

STX2 involved in several pathways and played different roles in them. We selected most pathways STX2 participated on our site, such as SNARE interactions in vesicular transport, Synaptic vesicle cycle, which may be useful for your reference. Also, other proteins which involved in the same pathway with STX2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
SNARE interactions in vesicular transport
GOSR1; STX4A; STX5AL; SEC22B; SEC22BB; STX11A; VAMP3; SEC22BA; STX6; BET1L
Synaptic vesicle cycle
ATP6V0A2; DNM3; ATP6V0A4; SYT1; ATP6V1G1; STXBP1; ATP6V0C; ATP6V1B2; SNAP25; CPLX2

Protein Function

STX2 has several biochemical functions, for example, SNAP receptor activity, SNARE binding, calcium-dependent protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by STX2 itself. We selected most functions STX2 had, and list some proteins which have the same functions with STX2. You can find most of the proteins on our site.
Function
Related Protein
Function SNAP receptor activity
Related Protein SEC22BA; GOSR1; STX11A; VTI1B; SNAP25B; STX2A; STX4A; SNAP23; YKT6; SNAP25
Function SNARE binding
Related Protein VAMP7; GOSR1; VAMP3; SEC22BA; STX1A; UNC13A; STX5A; LRRK2; VTI1A; VTI1B
Function calcium-dependent protein binding
Related Protein CALM1; TNNT3; CCDC167; RBM22; DDX5; SYN1; S100A4; MASP1; CPNE3; CLEC4M
Function protein binding
Related Protein ICA1; HGF; HMBOX1; APBA2; ZRANB2; KATNAL1; MAPK13; THBD; PDCD10; SOCS4
Function protein dimerization activity
Related Protein ASCL4; ATOH1; STX2; ARNTL1A; HIF3A; RIMKLB; HER11; TCF21; AHRR; ATOH7

Interacting Protein

STX2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with STX2 here. Most of them are supplied by our site. Hope this information will be useful for your research of STX2.
VAMP3

STX2 Related Articles

Diodati, ME; Bates, AH; et al. High Genotypic and Phenotypic Similarity Among Shiga Toxin-Producing Escherichia coli O111 Environmental and Outbreak Strains. FOODBORNE PATHOGENS AND DISEASE 12:235-243(2015).
Arimitsu, H; Sasaki, K; et al. Isolation of B subunit-specific monoclonal antibody clones that strongly neutralize the toxicity of Shiga toxin 2. MICROBIOLOGY AND IMMUNOLOGY 59:71-81(2015).