Recombinant Human Syntaxin 2, His-tagged

• Cat.No.: STX2-6854H
• Product Overview: Recombinant human STX2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 1-264aa
• Description: STX2 belongs to thesyntaxin/epimorphin family of proteins. Syntaxin family is cellular receptors for transport vesicles which participate in exocytosis in neutrophils. STX2 is a t-SNARE that localizes to the apical plasma membrane and intracellular vesicular structures.
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 50% glycerol,1mM DTT.
• Molecular Mass: 33.6 kDa (289aa) confirmed by MALDI-TOF
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSHMMRDRL PDLTACRKND DGDTVVVVEK DHFMDDFFHQ VEEIRNSIDK ITQYVEEVKK NHSIILSAPN PEGKIKEELE DLNKEIKKTA NKIRAKLKAI EQSFDQDESG NRTSVDLRIR RTQHSVLSRK FVEAMAEYNE AQTLFRERSK GRIQRQLEIT GRTTTDDELE EMLESGKPSI FTSDIISDSQ ITRQALNEIE SRHKDIMKLE TSIRELHEMF MDMAMFVETQ GEMINNIERN VMNATDYVEH AKEETKKAIK YQSKARRKK
• Purity: >95% by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -75°C. Avoid repeated freezing and thawing cycles.
• Concentration: 0.25 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: STX2 syntaxin 2 [ Homo sapiens ]
• Official Symbol: STX2
• Synonyms: STX2; syntaxin 2; EPIM, epimorphin , STX2A, STX2B, STX2C; syntaxin-2; EPM; epimorphin; EPIM; STX2A; STX2B; STX2C; MGC51014
• Gene ID: 2054
• mRNA Refseq: NM_194356
• Protein Refseq: NP_919337
• MIM: 132350
• UniProt ID: P32856
• Chromosome Location: 12q24
• Pathway: Botulinum neurotoxicity, organism-specific biosystem; Disease, organism-specific biosystem; Neuronal System, organism-specific biosystem; Proteolytic cleavage of SNARE complex proteins, organism-specific biosystem; SNARE interactions in vesicular transport, organism-specific biosystem; SNARE interactions in vesicular transport, conserved biosystem; Synaptic vesicle cycle, organism-specific biosystem
• Function: SNAP receptor activity; SNARE binding; calcium-dependent protein binding; protein binding