sumo2
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  • Official Full Name
  • SMT3 suppressor of mif two 3 homolog 2
  • Background
  • This gene encodes a protein that is a member of the SUMO (small ubiquitin-like modifier) protein family. It functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. It is not active until the last two amino acids of the carboxy-terminus have been cleaved off. Numerous pseudogenes have been reported for this gene. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
  • Synonyms
  • SUMO2; SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae); SMT3 (suppressor of mif two 3, yeast) homolog 2 , SMT3 suppressor of mif two 3 homolog 2 (yeast) , SMT3H2; small ubiquitin-related modifier 2; SMT3B; sentrin 2; SMT3 homolog 2; ubiquitin-like
Cat.#:SUMO2-432HTag:GST
Source (Host):BacteriaSpecies:Human
Product nameRecombinant Human SUMO2 Protein, GST-tagged
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Cat.#:SUMO2-433HTag:
Source (Host):BacteriaSpecies:Human
Product nameRecombinant Human SUMO2 Protein
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Cat.#:SUMO2-435HTag:His
Source (Host):BacteriaSpecies:Human
Product nameRecombinant Human SUMO2 Protein, His-tagged
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Cat.#:SUMO2-3016HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human SUMO2 Protein, MYC/DDK-tagged
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Cat.#:SUM02-13HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human SUM02
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Cat.#:SUMO2-250HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human SUMO2, His-tagged
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Cat.#:SUMO2-28787THTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human SUMO2
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Cat.#:SUMO2-587HTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human SUMO2
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Cat.#:SUMO2-588HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human SUMO2, His-tagged
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Cat.#:SUMO2-590HTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human SUMO2
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Cat.#:SUMO2-591HTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human SUMO2
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Cat.#:SUMO2-592HTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human SUMO2
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Cat.#:SUMO2-16238MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse SUMO2 Protein
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Cat.#:SUMO2-5840RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat SUMO2 Protein
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Cat.#:SUMO2-991CTag:His
Source (Host):Mammalian CellsSpecies:Cynomolgus Monkey
Product nameRecombinant Cynomolgus SUMO2 Protein, His-tagged
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Cat.#:SUMO2-4561RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey SUMO2 Protein, His-tagged
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Cat.#:SUMO2-3612CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken SUMO2
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Cat.#:SUMO2-1722HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human SUMO2 cell lysate
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Involved Pathway

SUMO2 involved in several pathways and played different roles in them. We selected most pathways SUMO2 participated on our site, such as RNA transport, which may be useful for your reference. Also, other proteins which involved in the same pathway with SUMO2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
RNA transport
EIF4E1C; EIF4EBP3L; EIF4G1A; EIF3EB; EIF3A; NCBP2; TACC3; EEF1A1L2; KPNB1; EIF4BA

Protein Function

SUMO2 has several biochemical functions, for example, poly(A) RNA binding, protein binding, protein tag. Some of the functions are cooperated with other proteins, some of the functions could acted by SUMO2 itself. We selected most functions SUMO2 had, and list some proteins which have the same functions with SUMO2. You can find most of the proteins on our site.
Function
Related Protein
Function poly(A) RNA binding
Related Protein MOV10; AKAP8; EBI3; TCP1; MKI67IP; ZC3H18; SRP54; RPL5; CELF1; RPL7L1
Function protein binding
Related Protein PRKAA1; WIF1; COQ7; TSC1; SOCS7; NEFL; CCDC36; RASGRP3; GNB1B; ADAP2
Function protein tag
Related Protein ISG15; SUMO3B; SUMO3; UBL5; SUMO4; RNF41; SUMO2; SUMO2B; SUMO3A; NFATC2IP
Function ubiquitin protein ligase binding
Related Protein RNF31; MDM2; FLJ11011L; GPI; DBT; MYOD1; PRKAR2A; CDKN1A; CLU; MAGEA2B

Interacting Protein

SUMO2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SUMO2 here. Most of them are supplied by our site. Hope this information will be useful for your research of SUMO2.
CHD3; PELP1; USPL1; uspl1; HOMEZ; SENP2; USP25

SUMO2 Related Articles

Collaud, S; Tischler, V; et al. Lung neuroendocrine tumors: correlation of ubiquitinylation and sumoylation with nucleo-cytosolic partitioning of PTEN. BMC CANCER 15:-(2015).
Bund, T; Spoden, GA; et al. An L2 SUMO interacting motif is important for PML localization and infection of human papillomavirus type 16. CELLULAR MICROBIOLOGY 16:1179-1200(2014).