Recombinant Human SUMO2 Protein, His-tagged
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|Product Overview :||Recombinant Human SUMO2(Q90P) Protein is produced by Bacteria expression system. This protein is fused with a His tag.|
SUMO (small Ub-related modifier) is a Ub-like protein. Three types of SUMO are most commonly studied, SUMO 1, SUMO 2, and SUMO 3. SUMO 2 and SUMO 3 are almost identical isoforms and thus share many functions. Like Ub, SUMO can be conjugated to its target proteins as a polymeric chain. However, SUMO 1 forms chains inefficiently as compared to SUMO 2 and SUMO 3. SUMO is conjugated to target proteins by the E1 (SAE1/SAE2), E2 (Ube2I or Ubc9), E3 (RanBP2/Nup358, amongst others). Protein sumoylation is involved in many cellular processes including gene transcription.
The SUMO2(Q90P) mutant can still form polySUMO2 chains, but these chains are often resistant to desumolyation.
|Form :||20 mM Tris, 150 mM NaCl, 2 mM βME, 10% Glycerol|
|Molecular Mass :||10.9 kDa|
|Purity :||> 95 % by SDS-PAGE|
|Storage :||Store at -80 centigrade; avoid multiple freeze-thaw cycles.|
|Gene Name :||SUMO2 small ubiquitin-like modifier 2 [ Homo sapiens (human) ]|
|Official Symbol :||SUMO2|
|Synonyms :||HSMT3; SMT3B; SUMO3; Smt3A; SMT3H2; MGC117191|
|Gene ID :||6613|
|mRNA Refseq :||NM_006937|
|Protein Refseq :||NP_008868|
|UniProt ID :||P61956|
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