|Official Full Name||WEE1 homolog|
|Background||Entry of all eukaryotic cells into mitosis is regulated by activation of cdc2 kinase. The critical regulatory step in activating cdc2 during progression into mitosis appears to be dephosphorylation of Tyr15 and Thr14 (1,2). Phosphorylation at Tyr15 and Th|
|Synonyms||WEE1; WEE1 homolog (S. pombe); wee1+ (S. pombe) homolog; wee1-like protein kinase; wee1A kinase; WEE1+ homolog; WEE1A; WEE1hu; FLJ16446; DKFZp686I18166|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
WEE1 involved in several pathways and played different roles in them. We selected most pathways WEE1 participated on our site, such as Cell cycle, which may be useful for your reference. Also, other proteins which involved in the same pathway with WEE1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Cell cycle||TUBG1; SMAD3A; CDH1-A; ARF1; TTK; HDAC5; PLK1; MCM10; TFDP2; OIP5|
WEE1 has several biochemical functions, for example, ATP binding, magnesium ion binding, non-membrane spanning protein tyrosine kinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by WEE1 itself. We selected most functions WEE1 had, and list some proteins which have the same functions with WEE1. You can find most of the proteins on our site.
|ATP binding||HSPH1; MYH7B; SUPV3L1; UBE2G1B; SARS2; OASL1; PSKH1; PI4KA; PRKACAA; KCNJ1|
|magnesium ion binding||THTPA; NUAK2; AASDHPPT; STK36; PTENA; ATP9B; PPM1B; ATP8B3; STK4; IDH3B|
|non-membrane spanning protein tyrosine kinase activity||CLK1; MELK; ZAP70; EIF2AK2; WEE2; JAK3; JAK2; HCK; PTK2BB; FYNA|
|protein binding||MMP15; APOH; LPA; NCOR1; KPNA1; FAF2; ATG3; MPZL1L; GNL3; ATP6AP2|
|protein tyrosine kinase activity||MAP2K2; BCR; PTK2BB; KDR; IGF1RA; AXL; PTK2; JAK2B; MAP3K11; EPHA4B|
WEE1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with WEE1 here. Most of them are supplied by our site. Hope this information will be useful for your research of WEE1.
YWHAB; FBXW11; YWHAZ; BTRC; N/A; PLK1; Cdk1; SFN; YWHAG; NEK6; czc8004