A2ML1 involved in several pathways and played different roles in them. We selected most pathways A2ML1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with A2ML1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name |
Pathway Related Protein |
A2ML1 has several biochemical functions, for example, peptidase inhibitor activity, serine-type endopeptidase inhibitor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by A2ML1 itself. We selected most functions A2ML1 had, and list some proteins which have the same functions with A2ML1. You can find most of the proteins on our site.
| Function |
Related Protein |
| peptidase inhibitor activity |
SERPINB10; WFDC15B; SERPINA3C; COL28A1; SSPO; SERPINB11; SPINK8; PTTG2; COL7A1; SERPINA1D |
| serine-type endopeptidase inhibitor activity |
OVST; SERPINA12; SERPINE1; SERPINB12; COL28A1; SERPINA3M; SERPINB6; OVAL; SERPINB1B; SERPINA3K |
A2ML1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with A2ML1 here. Most of them are supplied by our site. Hope this information will be useful for your research of A2ML1.
RASSF9
Poot, AM; Diercks, GFH; et al. Laboratory diagnosis of paraneoplastic pemphigus. BRITISH JOURNAL OF DERMATOLOGY 169:1016-1024(2013).
Numata, S; Teye, K; et al. Anti-Alpha-2-Macroglobulin-Like-1 Autoantibodies Are Detected Frequently and May Be Pathogenic in Paraneoplastic Pemphigus. JOURNAL OF INVESTIGATIVE DERMATOLOGY 133:1785-1793(2013).
Schepens, I; Jaunin, F; et al. The Protease Inhibitor Alpha-2-Macroglobuline-Like-1 Is the p170 Antigen Recognized by Paraneoplastic Pemphigus Autoantibodies in Human. PLOS ONE 5:-(2010).
Galliano, MF; Toulza, E; et al. Binding of alpha 2ML1 to the Low Density Lipoprotein Receptor-Related Protein 1 (LRP1) Reveals a New Role for LRP1 in the Human Epidermis. PLOS ONE 3:-(2008).
