Recombinant Human A2ML1 Protein, Myc/DDK-tagged, C13 and N15-labeled
| Cat.No. : | A2ML1-1627H |
| Product Overview : | A2ML1 MS Standard C13 and N15-labeled recombinant protein (NP_653271) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
- Specification
- Gene Information
- Related Products
| Description : | This gene encodes a member of the alpha-macroglobulin superfamily. The encoded protein is thought to be an N-glycosylated monomeric protein that acts as an inhibitor of several proteases. It has been shown to form covalent interactions with proteases, and has been reported as the p170 antigen recognized by autoantibodies in the autoimmune disease paraneoplastic pemphigus (PNP; PMID:20805888). Mutations in these gene have also been associated with some cases of Noonan syndrome (NS; PMID:24939586) as well as some cases of otitis media (PMID:26121085). Alternative splicing results in multiple transcript variants encoding different isoforms. |
| Source : | HEK293 |
| Species : | Human |
| Tag : | Myc/DDK |
| Molecular Mass : | 161 kDa |
| AA Sequence : | MWAQLLLGMLALSPAIAEELPNYLV TLPARLNFPSVQKVCLDLSPGYSDV KFTVTLETKDKTQKLLEYSGLKKRH LHCISFLVPPPAGGTEEVATIRVSG VGNNISFEEKKKVLIQRQGNGTFVQ TDKPLYTPGQQVYFRIVTMDSNFVP VNDKYSMVELQDPNSNRIAQWLEVV PEQGIVDLSFQLAPEAMLGTYTVAV AEGKTFGTFSVEEYVLPKFKVEVVE PKELSTVQESFLVKICCRYTYGKPM LGAVQVSVCQKANTYWYREVEREQL PDKCRNLSGQTDKTGCFSAPVDMAT FDLIGYAYSHQINIVATVVEEGTGV EANATQNIYISPQMGSMTFEDTSNF YHPNFPFSGKIRVRGHDDSFLKNHL VFLVIYGTNGTFNQTLVTDNNGLAP FTLETSGWNGTDVSLEGKFQMEDLV YNPEQVPRYYQNAYLHLRPFYSTTR SFLGIHRLNGPLKCGQPQEVLVDYY IDPADASPDQEISFSYYLIGKGSLV MEGQKHLNSKKKGLKASFSLSLTFT SRLAPDPSLVIYAIFPSGGVVADKI QFSVEMCFDNQVSLGFSPSQQLPGA EVELQLQAAPGSLCALRAVDESVLL LRPDRELSNRSVYGMFPFWYGHYPY QVAEYDQCPVSGPWDFPQPLIDPMP QGHSSQRSIIWRPSFSEGTDLFSFF RDVGLKILSNAKIKKPVDCSHRSPE YSTAMGAGGGHPEAFESSTPLHQAE DSQVRQYFPETWLWDLFPIGNSGKE AVHVTVPDAITEWKAMSFCTSQSRG FGLSPTVGLTAFKPFFVDLTLPYSV VRGESFRLTATIFNYLKDCIRVQTD LAKSHEYQLESWADSQTSSCLCADE AKTHHWNITAVKLGHINFTISTKIL DSNEPCGGQKGFVPQKGRSDTLIKP VLVKPEGVLVEKTHSSLLCPKGKVA SESVSLELPVDIVPDSTKAYVTVLG DIMGTALQNLDGLVQMPSGCGEQNM VLFAPIIYVLQYLEKAGLLTEEIRS RAVGFLEIGYQKELMYKHSNGSYSA FGERDGNGNTWLTAFVTKCFGQAQK FIFIDPKNIQDALKWMAGNQLPSGC YANVGNLLHTAMKGGVDDEVSLTAY VTAALLEMGKDVDDPMVSQGLRCLK NSATSTTNLYTQALLAYIFSLAGEM DIRNILLKQLDQQAIISGESIYWSQ KPTPSSNASPWSEPAAVDVELTAYA LLAQLTKPSLTQKEIAKATSIVAWL AKQRNAYGGFSSTQDTVVALQALAK YATTAYMPSEEINLVVKSTENFQRT FNIQSVNRLVFQQDTLPNVPGMYTL EASGQGCVYVQTVLRYNILPPTNMK TFSLSVEIGKARCEQPTSPRSLTLT IHTSYVGSRSSSNMAIVEVKMLSGF SPMEGTNQLLLQQPLVKKVEFGTDT LNIYLDELIKNTQTYTFTISQSVLV TNLKPATIKVYDYYLPDEQATIQYS DPCETRTRPLEQKLISEEDLAANDI LDYKDDDDKV |
| Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : | 50 μg/mL as determined by BCA |
| Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
| Gene Name : | A2ML1 alpha-2-macroglobulin-like 1 [ Homo sapiens (human) ] |
| Official Symbol : | A2ML1 |
| Synonyms : | A2ML1; alpha-2-macroglobulin-like 1; C3 and PZP like, alpha 2 macroglobulin domain containing 9, CPAMD9; alpha-2-macroglobulin-like protein 1; FLJ25179; C3 and PZP-like, alpha-2-macroglobulin domain containing 9; CPAMD9; FLJ16045; FLJ39129; FLJ41597; FLJ41598; FLJ41607; DKFZp686C1729; DKFZp686D2011; DKFZp686G1812; DKFZp686L1821; DKFZp686O1010; |
| Gene ID : | 144568 |
| mRNA Refseq : | NM_144670 |
| Protein Refseq : | NP_653271 |
| MIM : | 610627 |
| UniProt ID : | A8K2U0 |
Products Types
| ◆ Recombinant Protein | ||
| A2ML1-240H | Recombinant Human A2ML1 Protein, His (Fc)-Avi-tagged | +Inquiry |
| A2ML1-0043H | Recombinant Human A2ML1 Protein (Gln1119-Thr1348), N-His-tagged | +Inquiry |
| A2ML1-827H | Active Recombinant Human A2ML1 Protein, His-tagged | +Inquiry |
| A2ML1-1833H | Recombinant Human A2ML1 protein, GST-tagged | +Inquiry |
| a2ML1-3328H | Recombinant Human a2ML1 | +Inquiry |
| ◆ Lysates | ||
| A2ML1-2105HCL | Recombinant Human A2ML1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Ask a Question for All A2ML1 Products
Required fields are marked with *
My Review for All A2ML1 Products
Required fields are marked with *
0
Inquiry Basket
