actc1

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actc1

Official Full Name Actin, Alpha, Cardiac Muscle 1
Background Actins are highly conserved proteins that are involved in various types of cell motility. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to four others. The protein encoded by this gene belongs to the actin family which is comprised of three main groups of actin isoforms, alpha, beta, and gamma. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus.
Synonyms ACTC1; actin, alpha, cardiac muscle 1; ACTC; ASD5; CMD1R; CMH11; LVNC4; OTTHUMP00000160081; alpha-cardiac actin
    • Species :
    • Bovine
    • Chicken
    • Human
    • Mouse
    • Rat
    • Source :
    • Bovine cardiac
    • Bovine cardiac muscle
    • Bovine Heart
    • E. coli
    • E.coli
    • E.Coli or Yeast
    • HEK293
    • HEK293T
    • Human Heart
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • T7
    • MYC/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human ACTC1-1705H Recombinant Human ACTC1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human ACTC1-214H Recombinant Human ACTC1 Protein, GST-tagged Wheat Germ GST
    Human ACTC1-244H Recombinant Human ACTC1 protein, GST-tagged E. coli GST
    Human ACTC1-5294H Native Human Actin, Alpha, Cardiac Muscle 1 Human Heart N/A
    Human ACTC1-6835H Recombinant Human ACTC1 protein, His & T7-tagged E.coli His/T7
    Human ACTC1-9065HCL Recombinant Human ACTC1 293 Cell Lysate HEK293 N/A
    Human ACTC1-9333H Recombinant Human ACTC1, His-tagged E.coli His
    Mouse ACTC1-1241M Recombinant Mouse ACTC1 Protein Mammalian Cell His
    Mouse Actc1-3089M Recombinant Mouse Actc1, His-tagged E.Coli or Yeast His
    Mouse Actc1-813M Recombinant Mouse Actc1 Protein, MYC/DDK-tagged HEK293T MYC/DDK
    Rat ACTC1-479R Recombinant Rat ACTC1 Protein Mammalian Cell His
    Bovine ACTC1-166B Native bovine ACTC1 Bovine Heart N/A
    Bovine ACTC1-852B Native Bovine ACTC1 Protein Bovine cardiac muscle N/A
    Bovine ACTC1-885B Native Bovine ACTC1 Protein, Pyrene labeled Bovine cardiac N/A
    Chicken ACTC1-3520C Recombinant Chicken ACTC1 Mammalian Cell His

    actc1 involved in several pathways and played different roles in them. We selected most pathways actc1 participated on our site, such as Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Hypertrophic cardiomyopathy (HCM), which may be useful for your reference. Also, other proteins which involved in the same pathway with actc1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cardiac muscle contraction ACTC1B; COX5B2; TNNT2; SLC8A1; COX6A1; UQCRC2; CACNA1D; ACTC1A; CACNB4; COX6B2
    Adrenergic signaling in cardiomyocytes PPP2CA; ATP2B1A; CACNG1A; MAPK12; CAMK2D; PIK3R3B; PLCB2; SLC8A1; PPP2R1A; CACNA1SB
    Hypertrophic cardiomyopathy (HCM) CACNA2D1; MYL3; CACNA2D2; DES; SGCG; ITGB6; TNNI3; RYR2; SGCD; ITGA3
    Dilated cardiomyopathy CACNA2D4; CACNG1; ITGB5; ITGB8; CACNA2D2; ITGA10; DES; SGCB; PRKACG; RYR2

    actc1 has several biochemical functions, for example, ATP binding, ATPase activity, myosin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by actc1 itself. We selected most functions actc1 had, and list some proteins which have the same functions with actc1. You can find most of the proteins on our site.

    Function Related Protein
    ATP binding STK31; DDX59; MYO1C; PRKX; ATP1A1A.5; PKMYT1; TNIKA; MCM8; MYO7AA; FGFR3
    ATPase activity KIF25; TOR1B; ABCD3A; ATP13A3; EIF4A1B; ATAD1; PSMC3; KIF15; PSMC6; KIF21A
    myosin binding KIRREL; NPHS1; GIPC1; ACTA1; CALM; VAMP2; SMYD1B; ARFGEF1; FXYD1; ARFGEF2

    actc1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with actc1 here. Most of them are supplied by our site. Hope this information will be useful for your research of actc1.

    ESR1; GAPDH; C1QTNF9; MYBPC3; TNNI3K; TRIM63; BCL11A; ASH2L; MPC1; ere_dna; MYC; VCAM1; ARRB2; HTR7; MYH9

    Tian, T; Wang, JZ; et al. A low prevalence of sarcomeric gene variants in a Chinese cohort with left ventricular non-compaction. HEART AND VESSELS 30:258-264(2015).
    Chen, CD; Yu, ZQ; et al. Evaluating the Association between Pathological Myopia and SNPs in RASGRFI, ACTCI and GJD2 Genes at Chromosome 15q14 and 15q25 in a Chinese Population. OPHTHALMIC GENETICS 36:1-7(2015).

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