Recombinant Human AK2 Protein, GST-tagged

• Cat.No.: AK2-484H
• Product Overview: Human AK2 full-length ORF ( AAH09405, 1 a.a. - 239 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: Adenylate kinases are involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate groups among adenine nucleotides. Three isozymes of adenylate kinase, namely 1, 2, and 3, have been identified in vertebrates; this gene encodes isozyme 2. Expression of these isozymes is tissue-specific and developmentally regulated. Isozyme 2 is localized in the mitochondrial intermembrane space and may play a role in apoptosis. Mutations in this gene are the cause of reticular dysgenesis. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 1 and 2.[provided by RefSeq, Nov 2010]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 52.03 kDa
• AA Sequence: MAPSVPAAEPEYPKGIRAVLLGPPG AGKGTQAPRLAENFCVCHLATGDML RAMVASGSELGKKLKATMDAGKLVS DEMVVELIEKNLETPLCKNGFLLDG FPRTVRQAEMLDDLMEKRKEKLDSV IEFSIPDSLLIRRITGRLIHPKSGR SYHEEFNPPKEPMKDDITGEPLIRR SDDNEKALKIRLQAYHTQTTPLIEY YRKRGIHSAIDASQTPDVVFASILA AFSKATCKDLVMFI
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: AK2 adenylate kinase 2 [ Homo sapiens ]
• Official Symbol: AK2
• Synonyms: AK2; adenylate kinase 2; adenylate kinase 2, mitochondrial; ATP-AMP transphosphorylase 2; adenylate kinase isoenzyme 2, mitochondrial; ADK2; AK 2
• Gene ID: 204
• mRNA Refseq: NM_001199199
• Protein Refseq: NP_001186128
• MIM: 103020
• UniProt ID: P54819