Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

Recombinant Rat Ak2 Protein, His-tagged

Cat.No. : Ak2-511R
Product Overview : Recombinant Rat Ak2(Leu64~Ser232) fused with His tag at N-terminal was expressed in E. coli.
  • Specification
  • Gene Information
  • Related Products
Source : E. coli
Species : Rat
Tag : His
Form : PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Molecular Mass : 22.8kDa
Protein length : Leu64~Ser232
Endotoxin : <1.0EU per 1ug (determined by the LAL method)
Purity : > 95%
Applications : Positive Control; Immunogen; SDS-PAGE; WB.
If bio-activity of the protein is needed, please check active protein
Stability : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
Reconstitution : Reconstitute in PBS or others
Gene Name : Ak2 adenylate kinase 2 [ Rattus norvegicus ]
Official Symbol : Ak2
Synonyms : AK2; adenylate kinase 2; adenylate kinase 2, mitochondrial; AK 2; ATP-AMP transphosphorylase 2;
Gene ID : 24184
mRNA Refseq : NM_001033967
Protein Refseq : NP_001029139
UniProt ID : P29410

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Inquiry

  • Q&As
  • Reviews

Q&As (13)

Ask a question
Are there any drugs that target AK2 protein? 03/03/2023

Currently, there are no FDA-approved drugs targeting AK2 specifically. However, ongoing research is exploring the development of AK2 inhibitors as potential anti-cancer therapies.

Are there any natural compounds or dietary factors that impact AK2 protein activity? 02/05/2022

Some studies suggest that certain natural compounds and dietary factors, such as resveratrol, quercetin, and curcumin, can modulate AK2 protein activity. These compounds are known to exhibit antioxidant and anti-inflammatory properties, and their effects on AK2 activity may contribute to their potential health benefits.

How is AK2 protein regulated in the body? 01/14/2022

AK2 protein activity can be regulated at multiple levels. It can be modulated by post-translational modifications, such as phosphorylation and acetylation, which can affect its enzymatic activity and protein stability. The expression of AK2 can also be regulated by various factors, including hormones, growth factors, and environmental stimuli.

How is AK2 protein studied in the lab? 05/05/2021

AK2 protein is commonly studied using techniques such as gene cloning, recombinant protein expression, and enzymatic assays. Researchers also use cell and animal models to investigate the physiological and pathological roles of AK2 in various biological processes.

Is AK2 protein expressed in cancer cells? 01/13/2020

AK2 protein expression levels can vary in different cancer types. Some studies have reported elevated AK2 expression in certain cancers, including leukemia, breast cancer, and colorectal cancer. However, more research is needed to fully understand the role of AK2 in cancer development and progression.

How does AK2 protein interact with other proteins in the cellular network? 01/12/2020

AK2 can interact with various proteins in the cellular network, forming protein complexes involved in energy metabolism and other cellular processes. For example, it can interact with other enzymes involved in ATP production and utilization, as well as proteins involved in mitochondrial function and signaling pathways.

What are the other functions of AK2 protein besides energy metabolism? 04/12/2019

Besides its role in energy metabolism, AK2 protein has been implicated in other cellular processes, such as DNA replication and repair, apoptosis (programmed cell death), and signal transduction. It may also play a role in maintaining cellular redox balance and regulating cellular differentiation.

How is AK2 protein related to diseases? 03/28/2019

Mutations in the AK2 gene have been associated with several diseases, including reticular dysgenesis, a rare immunodeficiency disorder. In these cases, the dysfunctional AK2 enzyme impairs the production of ATP, leading to impaired immune system development and function.

What are the potential future research directions for AK2 protein? 05/24/2018

Further research on AK2 protein may focus on understanding its role in cellular energy metabolism, exploring its involvement in other diseases, and developing targeted therapies to modulate its activity for therapeutic purposes.

Are there any therapies targeting AK2 protein currently in clinical trials? 04/22/2018

As of now, there are no clinical trials specifically targeting AK2 protein. However, preclinical studies continue to explore the potential of AK2 inhibitors as therapeutic agents, particularly in cancer treatment. These inhibitors aim to disrupt the altered energy metabolism of cancer cells, which may provide a basis for future clinical trials.

Can AK2 protein be targeted for therapeutic purposes? 12/06/2017

AK2 protein has gained attention as a potential therapeutic target for certain diseases. Inhibiting AK2 activity may be beneficial in specific cancer types, as cancer cells often rely on altered energy metabolism for their growth and survival.

Can AK2 protein be used as a diagnostic marker for diseases? 02/27/2015

AK2 protein itself is not commonly used as a diagnostic marker for diseases. However, mutations in the AK2 gene have been linked to certain genetic disorders, such as reticular dysgenesis, and genetic testing for these mutations can be used for diagnostic purposes.

Where is AK2 protein found in the body? 01/14/2015

AK2 protein is found in various tissues and organs throughout the body, including the heart, brain, liver, and skeletal muscles.

Customer Reviews (3)

Write a review
Reviews
04/06/2023

    The remarkable traits of the AK2 protein, combined with the manufacturer's top-tier assistance, allows me to delve deeper into my research objectives

    03/08/2023

      With the AK2 protein in my arsenal and the unwavering support of the manufacturer's technical team, I am empowered to overcome any hurdles that may obstruct my progress.

      12/13/2022

        With an unrivaled depth of knowledge and expertise, ensuring a seamless and successful research experience.

        Ask a Question for All Ak2 Products

        Required fields are marked with *

        My Review for All Ak2 Products

        Required fields are marked with *

        0

        Inquiry Basket

        cartIcon
        logo

        FOLLOW US

        Terms and Conditions        Privacy Policy

        Copyright © 2024 Creative BioMart. All Rights Reserved.

        Contact Us

        • /

        Stay Updated on the Latest Bioscience Trends