ARL6IP5
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Official Full Name
ADP-ribosylation factor-like 6 interacting protein 5
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Overview
Expression of this gene is affected by vitamin A. The encoded protein of this gene may be associated with the cytoskeleton. A similar protein in rats may play a role in the regulation of cell differentiation. The rat protein binds and inhibits the cell membrane glutamate transporter EAAC1. The expression of the rat gene is upregulated by retinoic acid, which results in a specific reduction in EAAC1-mediated glutamate transport. -
Synonyms
ARL6IP5; ADP-ribosylation factor-like 6 interacting protein 5; PRA1 family protein 3; addicsin; protein JWa; ARL-6-interacting protein 5; prenylated Rab acceptor protein 2; glutamate transporter EAAC1-interacting protein; ADP-ribosylation-like factor 6 in;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Bos taurus (Bovine)
- Chicken
- Cynomolgus Monkey
- Gallus gallus (Chicken)
- Homo sapiens (Human)
- Human
- Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
- Mouse
- Mus musculus (Mouse)
- Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
- Rat
- Rattus norvegicus (Rat)
- Rhesus Macaque
- Sus scrofa (Pig)
- E.coli
- E.coli expression system
- HEK293
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- His|SUMO
- N/A
- Involved Pathway
- Protein Function
- Interacting Protein
- ARL6IP5 Related Articles
ARL6IP5 involved in several pathways and played different roles in them. We selected most pathways ARL6IP5 participated on our site, such as Glutamate Neurotransmitter Release Cycle, Neuronal System, Neurotransmitter Release Cycle, which may be useful for your reference. Also, other proteins which involved in the same pathway with ARL6IP5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Glutamate Neurotransmitter Release Cycle | CPLX2L;SLC17A7A;PPFIA4;CPLX1;SLC1A7A;PPFIA2;ARL6IP5B;UNC13B;SLC1A7B |
| Neuronal System | KCNA7;KCNK13B;CHRNE;KCNJ1A.3;DLG1L;KCNAB3;KCNAB1A;KCNAB2;KCNJ8 |
| Neurotransmitter Release Cycle | SLC6A1A;SYN3;ARL6IP5B;CPLX2L;BZRAP1;SNAP25A;LIN7B;SLC1A7A;Apba1 |
| Transmission across Chemical Synapses | SLC1A3A;CACFD1;RAB3AB;SLC1A7B;SLC17A7A;ARL6IP5A;CACNG2B;LIN7B;CACNB4B |
ARL6IP5 has several biochemical functions, for example, molecular_function, protein C-terminus binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ARL6IP5 itself. We selected most functions ARL6IP5 had, and list some proteins which have the same functions with ARL6IP5. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| molecular_function | LMF2B;GNB5A;TLE4;D19ERTD386E;DAW1;PDK3B;STAMBPB;FBXO36B;H2AFJ |
| protein C-terminus binding | SNF8;ERBB2;BLOC1S2A;KCNJ11;SNTG1;ERCC2;VPS4B;SNX17;DLG3 |
| protein binding | HLX;GRIN2D;MAGEA1;TEX19.1;DRD1A;MINOS1;SNRNP25;FAM59A;RAP1A |
ARL6IP5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ARL6IP5 here. Most of them are supplied by our site. Hope this information will be useful for your research of ARL6IP5.
RNF185; PRAF2; CCR5; q7ard3_yerpe
- Q&As
- Reviews
Q&As (4)
Ask a questionARL6IP5 mutations have been associated with Bardet-Biedl syndrome (BBS), a rare genetic disorder characterized by vision impairment, obesity, kidney dysfunction, and other symptoms. These findings suggest a role for ARL6IP5 in ciliopathies.
Investigating ARL6IP5 can enhance our understanding of the molecular mechanisms underlying Bardet-Biedl syndrome and other ciliopathies. It may also provide insights into intracellular trafficking pathways and potential therapeutic targets for related disorders.
Limited information is available on post-translational modifications of ARL6IP5. However, it is speculated that phosphorylation events may modulate its function and protein-protein interactions.
ARL6IP5 is involved in vesicular traffic between the Golgi apparatus and the plasma membrane. It interacts with other proteins, such as the small GTPase Arl6, to regulate processes like protein trafficking and secretion.
Customer Reviews (8)
Write a reviewthe ARL6IP5 protein's high quality and its compatibility with my experimental needs, coupled with the manufacturer's excellent technical support, create a valuable alliance that contributes to successful research endeavors.
The manufacturer's commitment to providing high-quality proteins is evident in their meticulous production process, ensuring the purity and reliability of the ARL6IP5 protein.
ARL6IP5 protein is highly recommended for researchers due to its excellent performance in WB experiments and its utility in protein electron microscopy structure analysis.
Its reliability and versatility make it an essential tool for investigating ARL6IP5 protein's expression, function, and structural characteristics.
This partnership enhances research productivity while ensuring accurate and meaningful outcomes.
By visualizing the structural features, interactions, and conformational changes of ARL6IP5, researchers gain valuable insights into its function and potential for therapeutic interventions.
The ARL6IP5 protein is characterized by its exceptional quality, making it an ideal choice to fulfill my experimental requirements.
The use of ARL6IP5 protein in such analyses provides valuable structural insights that contribute to the elucidation of ANO2's functional mechanisms and potential drug targeting sites.
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