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Official Full Name ADP-ribosylation factor-like 6 interacting protein 5
Background Expression of this gene is affected by vitamin A. The encoded protein of this gene may be associated with the cytoskeleton. A similar protein in rats may play a role in the regulation of cell differentiation. The rat protein binds and inhibits the cell membrane glutamate transporter EAAC1. The expression of the rat gene is upregulated by retinoic acid, which results in a specific reduction in EAAC1-mediated glutamate transport.
Synonyms ARL6IP5; ADP-ribosylation factor-like 6 interacting protein 5; PRA1 family protein 3; addicsin; protein JWa; ARL-6-interacting protein 5; prenylated Rab acceptor protein 2; glutamate transporter EAAC1-interacting protein; ADP-ribosylation-like factor 6 in
    • Species :
    • Chicken
    • Cynomolgus Monkey
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • SUMO
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human ARL6IP5-36HCL Recombinant Human ARL6IP5 lysate HEK293 N/A
    Human ARL6IP5-820H Recombinant Human ARL6IP5 protein, GST-tagged Wheat Germ GST
    Human ARL6IP5-95H Recombinant Human ARL6IP5 protein, His/SUMO-tagged E.coli His/SUMO
    Human ARL6IP5-9863H Recombinant Human ARL6IP5, GST-tagged E.coli GST
    Mouse ARL6IP5-1940M Recombinant Mouse ARL6IP5 Protein Mammalian Cell His
    Rat ARL6IP5-786R Recombinant Rat ARL6IP5 Protein Mammalian Cell His
    Cynomolgus Monkey ARL6IP5-312C Recombinant Cynomolgus ARL6IP5 Protein, His-tagged Mammalian Cell His
    Rhesus Macaque ARL6IP5-404R Recombinant Rhesus monkey ARL6IP5 Protein, His-tagged Mammalian Cell His
    Chicken ARL6IP5-1975C Recombinant Chicken ARL6IP5 Mammalian Cell His

    arl6ip5 involved in several pathways and played different roles in them. We selected most pathways arl6ip5 participated on our site, such as Glutamate Neurotransmitter Release Cycle, Neuronal System, Neurotransmitter Release Cycle, which may be useful for your reference. Also, other proteins which involved in the same pathway with arl6ip5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Glutamate Neurotransmitter Release Cycle SLC1A2A; SLC1A7A; RAB3AA; CCDC167; CPLX2L; PPFIA1; STXBP1A; SYT1A; RAB3AB; ARL6IP5
    Neuronal System KCNJ1A.4; KCNN3; KCNMA1; KCNA6A; LIN7B; CACNB4B; KCNQ3; SYN2; DDX1; PICK1
    Neurotransmitter Release Cycle PPFIA1; SLC6A1A; SLC1A7A; PPFIA2; SNAP25A; LIN7A; RERG; SLC6A11; SLC1A7B; SYN1
    Transmission across Chemical Synapses SLC1A2A; CAMKK1B; BZRAP1; SLC17A7A; PPFIA2; SYN1; SLC6A11; CACNG2B; SNAP25A; RAB3AB

    arl6ip5 has several biochemical functions, for example, molecular_function, protein C-terminus binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by arl6ip5 itself. We selected most functions arl6ip5 had, and list some proteins which have the same functions with arl6ip5. You can find most of the proteins on our site.

    Function Related Protein
    molecular_function SINUP; WFDC15B; CFC1; PITPNAA; MYOM1A; TIMM8A2; C3orf75; ARL6IP5B; UEVLD; CAX1
    protein C-terminus binding ATP1B1; TERF2; PHB; TOP2B; VAMP2; PPM1A; MPDZ; CEP120; NCF2; LCK
    protein binding FBXO34; ZFHX3; RPH3AL; CNOT4; LOXL3; CCDC146; RGS14; MBP; DUT; C14orf166

    arl6ip5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with arl6ip5 here. Most of them are supplied by our site. Hope this information will be useful for your research of arl6ip5.

    RNF185; PRAF2; CCR5; q7ard3_yerpe

    Wu, Y; Yang, M; et al. Deficiency of osteoblastic Arl6ip5 impaired osteoblast differentiation and enhanced osteoclastogenesis via disturbance of ER calcium homeostasis and induction of ER stress-mediated apoptosis. CELL DEATH & DISEASE 5:-(2014).
    Liu, X; Wang, SY; et al. Synergistic Role between p53 and JWA: Prognostic and Predictive Biomarkers in Gastric Cancer. PLOS ONE 7:-(2012).

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