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Official Full Name ATPase, Na+/K+ transporting, beta 3 polypeptide
Background The protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes a beta 3 subunit. This gene encodes a beta 3 subunit. A pseudogene exists for this gene, and it is located on chromosome 2.
Synonyms ATP1B3; ATPase, Na+/K+ transporting, beta 3 polypeptide; sodium/potassium-transporting ATPase subunit beta-3; CD298; FLJ29027; Na, K-ATPase beta-3 polypeptide; sodium/potassium-dependent ATPase beta-3 subunit; sodium/potassium-dependent ATPase subunit bet
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • His
    • T7
    • MYC/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Mouse Atp1b3-664M Recombinant Mouse Atp1b3 Protein, MYC/DDK-tagged HEK293T MYC/DDK
    Human ATP1B3-184H Recombinant Human ATP1B3, His-tagged E.coli His
    Human ATP1b3-3767H Recombinant Human ATP1b3, His-tagged, T7 tagged E.coli His/T7
    Human ATP1B3-8610HCL Recombinant Human ATP1B3 293 Cell Lysate HEK293 N/A
    Human ATP1B3-967H Recombinant Human ATP1B3 protein Wheat Germ N/A
    Mouse ATP1B3-2118M Recombinant Mouse ATP1B3 Protein Mammalian Cell His
    Mouse Atp1b3-708M Recombinant Mouse Atp1b3 protein, His & T7-tagged E.coli His/T7
    Rat Atp1b3-709R Recombinant Rat Atp1b3 protein, His & T7-tagged E.coli His/T7
    Rat ATP1B3-857R Recombinant Rat ATP1B3 Protein Mammalian Cell His
    Rhesus Macaque ATP1B3-450R Recombinant Rhesus monkey ATP1B3 Protein, His-tagged Mammalian Cell His
    Chicken ATP1B3-7083C Recombinant Chicken ATP1B3 Mammalian Cell His

    atp1b3 involved in several pathways and played different roles in them. We selected most pathways atp1b3 participated on our site, such as cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, which may be useful for your reference. Also, other proteins which involved in the same pathway with atp1b3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    cGMP-PKG signaling pathway ATF4; ATP1B4; TRPC6; FXYD2; MEF2A; PPP3CB; PDE3B; GNAI2; PIK3R3; ATP1A2
    cAMP signaling pathway GABBR1; TNNI3; LIPE; MLLT4; CALM1; NFATC1; ORAI1; GRIN3B; PIK3CA; PDE3B
    Cardiac muscle contraction CACNB2; CACNG8; TNNT2; UQCRH; ATP1B4; ATP1A4; COX7A3; MYL2B; COX6B2; ATP1B2A
    Adrenergic signaling in cardiomyocytes ATP1A3; CAMK2D1; CACNA2D1; ADCY8; CREB3; CACNG2; ATP2B2; MYH15; PIK3CA; SLC8A1
    Insulin secretion ATP1A3; ATF4; INS; VAMP2; Adcy4; ATP1A2; RAPGEF4; RIMS2; PLCB1; PRKACG
    Thyroid hormone synthesis ATP1B1; ITPR3; SLC5A5; PRKACG; ATF4; HSPA5; ATP1B3; PLCB1; PRKACB; PLCB3
    Thyroid hormone signaling pathway TBC1D4; EP300; ACTB; HDAC2; THRB; ATP1B3; PLCB3; MAPK3; MAPK1; KAT2A
    Aldosterone-regulated sodium reabsorption INS; SLC9A3R2; PIK3R5; PIK3CA; ATP1B2; PIK3R2; SCNN1G; IGF1; INS1; SCNN1B
    Endocrine and other factor-regulated calcium reabsorption KLK1B1; PLCB2; ATP2B1; RAB11A; ATP1B4; DNM3; KLK2; KLK1B24; ATP1B2; FXYD2
    Proximal tubule bicarbonate reclamation PCK2; Car2; SLC4A4; SLC9A3; ATP1B1; ATP1B3; Car4; ATP1B4; PCK1; SLC38A3
    Salivary secretion PRKCB; PRH2; PRH1; TRPV6; LYZ2; CALM4; LPO; MUC5B; PLCB2; CALM2
    Gastric acid secretion CA2; PLCB2; GNAQ; MYLK; ATP1B2; Slc4a2; Adcy4; CALM4; CALM1; ITPR3
    Pancreatic secretion AMY2B; SCTR; PRSS1; BST1; SLC26A3; PLA2G3; PRKCG; ATP1B4; PLA2G2F; ITPR3
    Carbohydrate digestion and absorption ATP1B2; ATP1B1; ATP1A2; AMY2A; ATP1B3; AMY1B; TAS1R2; HKDC1; G6PC; PLCB2
    Protein digestion and absorption SLC36A1; SLC16A10; PRSS1; SLC15A1; LOC780933; PRSS2; COL7A1; SLC7A8; ELN; COL27A1
    Bile secretion ATP1A4; SLC22A1; ADCY9; HMGCR; PRKACB; NCEH1; ABCB1A; OSTA; CFTR; SLC2A1
    Mineral absorption Trf; TF; SLC26A9; SLC26A6; HEPH; SLC11A1; SLC8A1; ATP1B4; FXYD2; HMOX2

    atp1b3 has several biochemical functions, for example, ATPase activator activity, ATPase binding, sodium:potassium-exchanging ATPase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by atp1b3 itself. We selected most functions atp1b3 had, and list some proteins which have the same functions with atp1b3. You can find most of the proteins on our site.

    Function Related Protein
    ATPase activator activity AHSA1; MYBPC3; DNAJC19; ATP1B3; DNAJB1; TOR1AIP1; RAB4A; ATP1B2; ATP1B1; DNAJC15
    ATPase binding GRIN2A; LCK; ATPIF1; TOR1AIP1; BBC3; PKD2; METTL21A; SLN; ATP6V0A2; ATP1B3
    sodium:potassium-exchanging ATPase activity ATP1A2A; ATP1A3; ATP1A2; ATP1A1A.2; ATP1B3; ATP1A1B; ATP1A1A.3; FXYD2; ATP1A3B; ATP12A
    contributes_to sodium:potassium-exchanging ATPase activity ATP1A1; ATP1B1; ATP1A2; ATP1B2; ATP1B3

    atp1b3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with atp1b3 here. Most of them are supplied by our site. Hope this information will be useful for your research of atp1b3.

    PTP4A3; b3xyc5_sollc; cona_canen; 1C; P

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