ATP1B3

  • Official Full Name

    ATPase, Na+/K+ transporting, beta 3 polypeptide

  • Overview

    The protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes a beta 3 subunit. This gene encodes a beta 3 subunit. A pseudogene exists for this gene, and it is located on chromosome 2.
  • Synonyms

    ATP1B3; ATPase, Na+/K+ transporting, beta 3 polypeptide; sodium/potassium-transporting ATPase subunit beta-3; CD298; FLJ29027; Na, K-ATPase beta-3 polypeptide; sodium/potassium-dependent ATPase beta-3 subunit; sodium/potassium-dependent ATPase subunit bet;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Gallus gallus (Chicken)
  • Homo sapiens (Human)
  • Human
  • Mouse
  • Mus musculus (Mouse)
  • Mus Musculus (Mouse)
  • Rat
  • Rhesus Macaque
  • Xenopus laevis (African clawed frog)
  • E.coli
  • E.coli expression system
  • HEK293
  • HEK293T
  • Human Cells
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • C
  • His
  • Fc
  • His (Fc)
  • Avi
  • His|T7
  • MYC
  • DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human ATP1B3-967H Recombinant Human ATP1B3 protein Wheat Germ N/A
Human ATP1b3-3767H Recombinant Human ATP1b3, His-tagged, T7 tagged E.coli His/T7 279
Human ATP1B3-184H Recombinant Human ATP1B3, His-tagged E.coli His 57- 279aa
Human ATP1B3-8610HCL Recombinant Human ATP1B3 293 Cell Lysate HEK293 N/A
Human ATP1B3-151H Recombinant Human ATP1B3 Protein, His-tagged Human Cells His
Human ATP1B3-1431H Recombinant Human ATP1B3 Protein (Met61-Phe273), N-His tagged E.coli N-His Met61-Phe273
Human ATP1B3-1167HF Recombinant Full Length Human ATP1B3 Protein In Vitro Cell Free System 279 amino acids
Human ATP1B3-4708H Recombinant Human ATP1B3 Protein (Thr57-Ala279), C-His tagged Mammalian cells C-His Thr57-Ala279
Mouse ATP1B3-2118M Recombinant Mouse ATP1B3 Protein Mammalian Cell His
Mouse Atp1b3-708M Recombinant Mouse Atp1b3 protein, His & T7-tagged E.coli His/T7 Met61~Arg277 (Accession # P97370)
Mouse Atp1b3-664M Recombinant Mouse Atp1b3 Protein, MYC/DDK-tagged HEK293T MYC/DDK
Mouse ATP1B3-852M-B Recombinant Mouse ATP1B3 Protein Pre-coupled Magnetic Beads HEK293
Mouse ATP1B3-01M Recombinant Mouse ATP1B3 Protein, Fc-tagged E.coli Fc
Mouse ATP1B3-852M Recombinant Mouse ATP1B3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat Atp1b3-709R Recombinant Rat Atp1b3 protein, His & T7-tagged E.coli His/T7 Asn66~Phe273 (Accession # Q63377)
Rat ATP1B3-857R Recombinant Rat ATP1B3 Protein Mammalian Cell His
Rat ATP1B3-513R-B Recombinant Rat ATP1B3 Protein Pre-coupled Magnetic Beads HEK293
Rat ATP1B3-513R Recombinant Rat ATP1B3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Gallus gallus (Chicken) RFL-19415GF Recombinant Full Length Chicken Sodium/Potassium-Transporting Atpase Subunit Beta-3(Atp1B3) Protein, His-Tagged E.coli expression system His Full Length (1-280)
Homo sapiens (Human) RFL-2180HF Recombinant Full Length Human Sodium/Potassium-Transporting Atpase Subunit Beta-3(Atp1B3) Protein, His-Tagged E.coli expression system His Full Length (1-279)
Mus musculus (Mouse) RFL-3810MF Recombinant Full Length Mouse Sodium/Potassium-Transporting Atpase Subunit Beta-3(Atp1B3) Protein, His-Tagged E.coli expression system His Full Length (1-278)
Mus Musculus (Mouse) ATP1B3-01H Recombinant mouse ATPase, Na+/K+ transporting, beta 3 polypeptide Protein, Fc-tagged E.coli Fc 450
Rhesus Macaque ATP1B3-450R Recombinant Rhesus monkey ATP1B3 Protein, His-tagged Mammalian Cell His
Rhesus Macaque ATP1B3-279R Recombinant Rhesus Macaque ATP1B3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque ATP1B3-279R-B Recombinant Rhesus Macaque ATP1B3 Protein Pre-coupled Magnetic Beads HEK293
Xenopus laevis (African clawed frog) RFL-4382XF Recombinant Full Length Xenopus Laevis Sodium/Potassium-Transporting Atpase Subunit Beta-3(Atp1B3) Protein, His-Tagged E.coli expression system His Full Length (1-277)
Chicken ATP1B3-7083C Recombinant Chicken ATP1B3 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

ATP1B3 involved in several pathways and played different roles in them. We selected most pathways ATP1B3 participated on our site, such as cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, which may be useful for your reference. Also, other proteins which involved in the same pathway with ATP1B3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
cGMP-PKG signaling pathwayPIK3R1;AGTR1A;ATP2B1;PRKG2;Adcy4;CALML5;CREB5;NFATC2;PPP3R1
cAMP signaling pathwayPRKACA;PDE3B;ATP1A4;PRKACB;NPY;PIK3R2;CAMK2A;GLI3;LOC100328615
Cardiac muscle contractionATP1A1;CACNG1;ATP1A2;COX7B2;MYL2B;TNNT2A;ATP2A2;UQCRFS1;COX7B
Adrenergic signaling in cardiomyocytesADCY1B;BCL2A;CREB3;TNNT2;TPM4;TPMA;GNAI2B;MYL4;PLCB2
Insulin secretionAdcy4;KCNMB1;PLCB1;ATP1B1;GPR119;PRKACA;ATP1A3;GIP;CREB3L1
Thyroid hormone synthesisPLCB1;PRKCA;ATP1B4;PRKCB;PAX8;ATP1A2;ATP1B1;GPX5;CANX
Thyroid hormone signaling pathwayPLCB3;EP300;PIK3R3;GATA4;HDAC2;ATP1B2;MED24;PLCD1;MAPK1
Aldosterone-regulated sodium reabsorptionPRKCA;MAPK3;PIK3R3;ALPHA-ENAC;ATP1B1;PIK3R1;SCNN1G;SLC9A3R2;ATP1B2
Endocrine and other factor-regulated calcium reabsorptionPRKACA;PLCB2;KLK1B11;PRKCB;KL;KLK1B3;FXYD2;GNAQ;ATP2B1
Proximal tubule bicarbonate reclamationSLC38A3;AQP1;SLC9A3;MDH1;CA2;CA4;ATP1A3;ATP1B3;ATP1B4
Salivary secretionCST2;AQP5;CALM3;PRKCA;PRKG1;CST4;PMAP-36;LYZ;AMY1B
Gastric acid secretionMYLK2;GNAI1;PRKCG;ATP1B1;SSTR2;CA2;GNAS;ATP1A3;Adcy4
Pancreatic secretionKCNMA1;PLCB1;AMY2A4;SCTR;PNLIPRP1;KCNQ1;PLA2G2E;PLA2G2A;PLA2G12A
Carbohydrate digestion and absorptionGNAT3;ATP1B2;ATP1B3;PIK3R1;ATP1B1;TAS1R2;PIK3CB;AMY2B;AMY2A
Protein digestion and absorptionLOC780933;PRSS3;COL6A6;MEP1B;CPA1;ATP1B4;COL6A4;SLC8A1;SLC15A1
Bile secretionPRKACA;KCNN2;ATP1B4;FAM84B;SLCO1A2;ABCG8;ADCY7;ATP1A2;SLC27A5
Mineral absorptionSLC46A1;MT1A;FTL;VDR;SLC34A2;HEPH;ATOX1;MT1G;ATP1B4

ATP1B3 has several biochemical functions, for example, ATPase activator activity, ATPase binding, sodium:potassium-exchanging ATPase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ATP1B3 itself. We selected most functions ATP1B3 had, and list some proteins which have the same functions with ATP1B3. You can find most of the proteins on our site.

Function Related Protein
ATPase activator activityAHSA1L;AHSA2;AHSA1;DNAJB6;DNAJC19;DNAJC24;TOR1AIP2;ATP1B3;MYBPC3
ATPase bindingUSP25;ATP6V0A2;ATP1B2;ATP6V0A1A;NKAIN1;ESR1;S100A1;ZNHIT6;DERL1
sodium:potassium-exchanging ATPase activityATP12A;ATP1A2A;ATP1A2;ATP1A1A.4;ATP1A3A;ATP1A1A.1;ATP1A1A.5;ATP1A4;ATP1B3
contributes_to sodium:potassium-exchanging ATPase activityATP1A1;ATP1B1;ATP1A2;ATP1B3;ATP1B2

ATP1B3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ATP1B3 here. Most of them are supplied by our site. Hope this information will be useful for your research of ATP1B3.

PTP4A3; b3xyc5_sollc; cona_canen; 1C; P

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