• Official Full Name

    ATPase, Na+/K+ transporting, beta 3 polypeptide

  • Background

    The protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes a beta 3 subunit. This gene encodes a beta 3 subunit. A pseudogene exists for this gene, and it is located on chromosome 2.
  • Synonyms

    ATP1B3; ATPase, Na+/K+ transporting, beta 3 polypeptide; sodium/potassium-transporting ATPase subunit beta-3; CD298; FLJ29027; Na, K-ATPase beta-3 polypeptide; sodium/potassium-dependent ATPase beta-3 subunit; sodium/potassium-dependent ATPase subunit bet;
    • Type:
    • Recombinant Proteins
    • Cell & Tissue Lysates
    • Protein Pre-coupled Magnetic Beads
    • Species :
    • Chicken
    • Human
    • Mouse
    • Mus Musculus (Mouse)
    • Rat
    • Rhesus Macaque
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Human Cells
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • Fc
    • His
    • His (Fc)
    • Avi
    • His|T7
    • MYC
    • DDK
    • N/A
    • N
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Chicken ATP1B3-7083C Recombinant Chicken ATP1B3 Mammalian Cell His
    Human ATP1B3-967H Recombinant Human ATP1B3 protein Wheat Germ N/A
    Human ATP1B3-8610HCL Recombinant Human ATP1B3 293 Cell Lysate HEK293 N/A
    Human ATP1B3-184H Recombinant Human ATP1B3, His-tagged E.coli His
    Human ATP1b3-3767H Recombinant Human ATP1b3, His-tagged, T7 tagged E.coli His/T7
    Human ATP1B3-151H Recombinant Human ATP1B3 Protein, His-tagged Human Cells His
    Human ATP1B3-0289H Recombinant Human ATP1B3 Protein (Met61-Phe273), His-tagged E.coli His
    Human ATP1B3-1432H Recombinant Human ATP1B3 Protein (Met61-Phe273), His tagged E.coli His
    Human ATP1B3-1431H Recombinant Human ATP1B3 Protein (Met61-Phe273), N-His tagged E.coli N-His
    Mouse ATP1B3-2118M Recombinant Mouse ATP1B3 Protein Mammalian Cell His
    Mouse Atp1b3-664M Recombinant Mouse Atp1b3 Protein, MYC/DDK-tagged HEK293T MYC/DDK
    Mouse Atp1b3-708M Recombinant Mouse Atp1b3 protein, His & T7-tagged E.coli His/T7
    Mouse ATP1B3-01M Recombinant Mouse ATP1B3 Protein, Fc-tagged E.coli Fc
    Mouse ATP1B3-852M-B Recombinant Mouse ATP1B3 Protein Pre-coupled Magnetic Beads HEK293
    Mouse ATP1B3-852M Recombinant Mouse ATP1B3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
    Mus Musculus (Mouse) ATP1B3-01H Recombinant mouse ATPase, Na+/K+ transporting, beta 3 polypeptide Protein, Fc-tagged E.coli Fc
    Rat ATP1B3-513R-B Recombinant Rat ATP1B3 Protein Pre-coupled Magnetic Beads HEK293
    Rat ATP1B3-857R Recombinant Rat ATP1B3 Protein Mammalian Cell His
    Rat Atp1b3-709R Recombinant Rat Atp1b3 protein, His & T7-tagged E.coli His/T7
    Rat ATP1B3-513R Recombinant Rat ATP1B3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
    Rhesus Macaque ATP1B3-279R-B Recombinant Rhesus Macaque ATP1B3 Protein Pre-coupled Magnetic Beads HEK293
    Rhesus Macaque ATP1B3-450R Recombinant Rhesus monkey ATP1B3 Protein, His-tagged Mammalian Cell His
    Rhesus Macaque ATP1B3-279R Recombinant Rhesus Macaque ATP1B3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
    • Involved Pathway
    • Protein Function
    • Interacting Protein

    ATP1B3 involved in several pathways and played different roles in them. We selected most pathways ATP1B3 participated on our site, such as cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, which may be useful for your reference. Also, other proteins which involved in the same pathway with ATP1B3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cardiac muscle contractionTPMA;ATP1A3B;TPM3;COX6A1;CACNB3;CACNG2A;ATP1A1A.1;CACNB3A;CACNA1DA
    Adrenergic signaling in cardiomyocytesPRKACB;MYH15;SCN1BB;CACNG3;CAMK2D;RYR2;PPP2R5EA;PRKACAB;ADRA1D
    Insulin secretionATP1A2;SLC2A2;ATP1A3;PLCB4;RIMS2;PRKCG;CAMK2A;KCNN3;ATP1B3
    Thyroid hormone synthesisATP1B2;PRKCG;ATP1A4;GPX5;SLC5A5;ITPR1;TPO;GPX7;ATP1A1
    Thyroid hormone signaling pathwayDIO1;PFKP;SRC;SLC9A1;NOTCH1;NOTCH4;PIK3R2;CCND1;DIO3
    Aldosterone-regulated sodium reabsorptionPIK3R1;ATP1B4;PIK3CG;MAPK3;SGK1;KCNJ1;ATP1B1;IGF1;ALPHA-ENAC
    Endocrine and other factor-regulated calcium reabsorptionATP2B1;PRKACB;KLK1B26;KL;ATP1B4;ATP1B1;KLK1B22;ESR1;KLK1
    Proximal tubule bicarbonate reclamationATP1A4;PCK2;SLC4A4;ATP1A2;GLS2;MDH1;Car4;GLS;ATP1A1
    Salivary secretionATP1A3;PRH1;ITPR3;PLCB1;CALML5;CALM2;GNAQ;CST1;PRKCG
    Gastric acid secretionITPR1;ACTB;CAMK2B;CALML5;GNAI2;PLCB4;GNAI1;CALML3;ATP1B1
    Pancreatic secretionGNAQ;ATP1B2;CPB1;KCNQ1;ATP1A3;PLA2G2A;CLCA1;CELA2A;ATP2A2
    Carbohydrate digestion and absorptionHK2;ATP1B2;SLC2A5;SI;ATP1B4;G6PC;Amy1;TAS1R3;HKDC1
    Protein digestion and absorptionCPA1;SLC36A1;KCNN4;COL10A1;ACE2;KCNE3;SLC7A7;COL21A1;KCNJ13
    Mineral absorptionSLC26A9;SLC40A1;MT1F;SLC8A1;SLC9A3;MT1G;STEAP1;HEPH;ATOX1

    ATP1B3 has several biochemical functions, for example, ATPase activator activity, ATPase binding, sodium:potassium-exchanging ATPase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ATP1B3 itself. We selected most functions ATP1B3 had, and list some proteins which have the same functions with ATP1B3. You can find most of the proteins on our site.

    Function Related Protein
    ATPase activator activityATP1B1;ATP1B3;DNAJC19;AHSA1L;DNAJC10;DNAJB6;RAB4A;AHSA2;DNAJC24
    sodium:potassium-exchanging ATPase activityATP1A2;ATP1A3;ATP1A1B;ATP1A1A.3;FXYD2;ATP1A1;ATP1A1A.5;ATP1A2A;ATP1A4
    contributes_to sodium:potassium-exchanging ATPase activityATP1A1;ATP1A2;ATP1B2;ATP1B3;ATP1B1

    ATP1B3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ATP1B3 here. Most of them are supplied by our site. Hope this information will be useful for your research of ATP1B3.

    PTP4A3; b3xyc5_sollc; cona_canen; 1C; P

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