ATP5B

  • Official Full Name

    ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide

  • Overview

    This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel consists of three main subunits (a, b, c). This gene encodes the beta subunit of the catalytic core.
  • Synonyms

    ATP5B; ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide; ATPSB; ATP synthase subunit beta, mitochondrial; mitochondrial; ATP 5B; ATP synthase subunit beta; ATP synthase subunit beta mitochondrial; ATPB; ATPB_HUMAN; ATPMB; Mitochondrial ATP Synthase Subunit Beta; Mitochondrial ATP synthetase beta subunit; OTTHUMP00000243448; OTTHUMP00000243449; OTTHUMP00000243452; mitochondrial ATP synthase beta subunit; mitochondrial ATP synthetase, beta subunit;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • E.coli
  • E.Coli or Yeast
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • Yeast
  • GST
  • His
  • His (Fc)
  • Avi
  • His|SUMO
  • SUMO
  • Myc
  • MYC
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human ATP5B-1137H Recombinant Human ATP5B Protein, His-tagged Yeast His
Human ATP5B-977H Recombinant Human ATP5B protein, GST-tagged Wheat Germ GST
Human ATP5B-26425TH Recombinant Human ATP5B, His-tagged E.coli His
Human ATP5B-8605HCL Recombinant Human ATP5B 293 Cell Lysate HEK293 N/A
Human ATP5B-1339HF Recombinant Full Length Human ATP5B Protein, GST-tagged In Vitro Cell Free System GST 529 amino acids
Mouse Atp5b-3710M Recombinant Mouse Atp5b, His-tagged E.Coli or Yeast His 529
Mouse ATP5B-2130M Recombinant Mouse ATP5B Protein Mammalian Cell His
Mouse ATP5B-2567M Recombinant Mouse ATP5B protein, His-SUMO & Myc-tagged E.coli His-SUMO & Myc 230-529aa
Mouse ATP5B-859M-B Recombinant Mouse ATP5B Protein Pre-coupled Magnetic Beads HEK293
Mouse Atp5b-669M Recombinant Mouse Atp5b Protein, MYC/DDK-tagged HEK293T MYC/DDK
Mouse ATP5B-346M Recombinant Mouse ATP5B Protein (47-529 aa), His-SUMO-tagged E.coli His/SUMO 47-529 aa
Mouse ATP5B-859M Recombinant Mouse ATP5B Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Atp5b-5348M Recombinant Mouse Atp5b protein, His-tagged Yeast His 47-529aa
Rat ATP5B-868R Recombinant Rat ATP5B Protein Mammalian Cell His
Rat ATP5B-524R-B Recombinant Rat ATP5B Protein Pre-coupled Magnetic Beads HEK293
Rat Atp5b-468R Recombinant Rat Atp5b Protein, His-tagged E.coli His Ala47~Ser529
Rat ATP5B-524R Recombinant Rat ATP5B Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish ATP5B-3029Z Recombinant Zebrafish ATP5B Mammalian Cell His
Chicken ATP5B-3042C Recombinant Chicken ATP5B Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

ATP5B involved in several pathways and played different roles in them. We selected most pathways ATP5B participated on our site, such as Oxidative phosphorylation, Metabolic pathways, Alzheimers disease, which may be useful for your reference. Also, other proteins which involved in the same pathway with ATP5B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Oxidative phosphorylationUQCR11;COX7B2;NDUFA9;ATP6V1AA;NDUFA2;NDUFS7;ATP5G1;NDUFA3;PPA2
Metabolic pathwaysPIGA;UQCRFS1;SGMS2;AMY2A5;CYP2P6;ACSBG2;ST8SIA5;OLAH;NDST3
Alzheimers diseaseCOX7A1;ATP5G3;NAE1;CASP7;NDUFB11;CALML5;COX7C;NDUFC1;NDUFS8
Parkinsons diseaseNDUFS2;UQCRC2;UBA7;UBE2G1;UBE2L3;NDUFB6;mt-Atp8;PRKACB;GNAI1
Huntingtons diseaseHDAC2;GRIN2B;HDAC1;UQCRC2;DNAH6;PPIF;ATP5G1;MT-ATP6;SLC25A31

ATP5B has several biochemical functions, for example, ATP binding, contributes_to ATPase activity, MHC class I protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ATP5B itself. We selected most functions ATP5B had, and list some proteins which have the same functions with ATP5B. You can find most of the proteins on our site.

Function Related Protein
ATP bindingTRIP13;MAPK3;OBSCN;AURKA;PFKFB2A;ATP9A;UBE2NB;FLT4;PRPS1
contributes_to ATPase activityMSH6;ATP5I;ATP1B1;ATP5A1;ATP6V1H;SFRP5;ATP5D;ATP5E;ATP5F1
MHC class I protein bindingTUBB4B;BCAP31;CD244;ATP5A1;ATP5B;VCP;LILRB1;TUBB;CD8A
protein bindingSTK16;CUBN;ATP6V1E2;SUGP1;UBE2M;AKAP12;FOXC2;MTERFD2;GMDS
proton-transporting ATP synthase activity, rotational mechanismATP5E;ATP5B;ATP5C1;ATP5O;ATP6AP1B;ATP6V0C;ATP6AP1;ATP5A1
proton-transporting ATPase activity, rotational mechanismATP6V0A1;ATP6AP1;ATP6V0A2B;ATP6V1AA;ATP6V1A;ATP6V0CA;ATP5B;ATP6V1E1B;ATP6V0A1B
transmembrane transporter activitySLC22A23;SV2B;SLC17A9;SLC22A13;ATP5J2;ATP5E;SLC2A13B;ATP5B;SLC2A9L1
transporter activitySYPB;RLBP1B;AP1S2;LCN9;FABP5;TIMM9;TTPAL;STEAP1;TMEM184C

ATP5B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ATP5B here. Most of them are supplied by our site. Hope this information will be useful for your research of ATP5B.

YWHAZ; ESR1; vpu; ATP5F1; PPP1CC; YWHAG; SIRT3; IKBKG; RPP14; TK1; CDK4; ANXA7; HMOX2; CDKN1A; PSME3; PIN1

  • Q&As
  • Reviews

Q&As (6)

Ask a question
What is the frequency of ATP5B mutations? 07/09/2022

ATP5B gene mutation frequency may be different in different diseases and populations, which needs further study.

How about the link between ATP5B protein and neurological diseases? 02/07/2021

It plays an important role in the nervous system and is associated with certain nervous system diseases such as Parkinson's disease and cerebral ischemia.

How are ATP5B mutations associated with disease? 10/15/2020

This gene mutations may lead to abnormal protein structure or function, which in turn affects the physiological function of the protein and is associated with specific diseases.

What are the regulatory mechanisms of ATP5B? 06/29/2020

ATP5B expression and function are affected by a variety of regulatory mechanisms, including regulation of transcription factors and epigenetic modifications.

How to evaluate the effect of ATP5B gene mutation on disease? 03/03/2019

Assessment of the effect of ATP5B mutations on disease often requires a comprehensive analysis of gene sequencing, protein function studies, and clinical and epidemiological studies.

In which tissues or organs is ATP5B highly expressed? 01/15/2019

It is highly expressed in multiple tissues and organs, especially metabolically active tissues such as heart, liver, and brain.

Customer Reviews (3)

Write a review
Reviews
05/22/2020

    The outstanding quality of proteins lies in their strong biological activity and their high purity during production, which is really rare.

    04/25/2020

      ATP5B has a very short half-life and shows a very high clearance rate, which makes its biological activity more stable.

      04/07/2019

        Because the production process is efficient and environmentally friendly, recombinant proteins can be produced on a large scale without negative environmental impacts.

        Ask a Question for All ATP5B Products

        Required fields are marked with *

        My Review for All ATP5B Products

        Required fields are marked with *

        logo

        FOLLOW US

        Terms and Conditions        Privacy Policy

        Copyright © 2024 Creative BioMart. All Rights Reserved.

        Contact Us

        • /

        Stay Updated on the Latest Bioscience Trends