ATP5B
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Official Full Name
ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide -
Overview
This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel consists of three main subunits (a, b, c). This gene encodes the beta subunit of the catalytic core. -
Synonyms
ATP5B;ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide;ATPSB;ATP synthase subunit beta, mitochondrial;mitochondrial;ATP 5B;ATP synthase subunit beta;ATP synthase subunit beta mitochondrial;ATPB;ATPB_HUMAN;ATPMB;Mitochondrial ATP Synthase Subunit Beta;Mitochondrial ATP synthetase beta subunit;OTTHUMP00000243448;OTTHUMP00000243449;OTTHUMP00000243452;mitochondrial ATP synthase beta subunit;mitochondrial ATP synthetase, beta subunit
Recombinant Proteins
- Rat
- Human
- Mouse
- Zebrafish
- Chicken
- E.coli
- Yeast
- Mammalian Cells
- E.Coli/Yeast
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- His
- GST
- Non
- Myc
- SUMO
- Avi
- Fc
- DDK
Involved Pathway
ATP5B involved in several pathways and played different roles in them. We selected most pathways ATP5B participated on our site, such as Oxidative phosphorylation,Metabolic pathways,Alzheimers disease, which may be useful for your reference. Also, other proteins which involved in the same pathway with ATP5B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Oxidative phosphorylation | NDUFB2,ATP6V1C1,UQCR10,COX6B2,ATP6V0D2,ATP5G3,NDUFB9,ATP6V1G2,NDUFC1,NDUFS8 |
| Alzheimers disease | ATP5G1,ATP5C1,UQCRC1,ADAM17,GRIN2C,NDUFS4,COX6B2,COX6C,GSK3B,GRIN2D |
| Huntingtons disease | ATP5J,CREB3L2,NDUFA4,TBPL1,NDUFS8,DCTN1,HIP1,IFT57,UQCRC1,UCP1 |
| Parkinsons disease | SDHD,NDUFB3,COX6B2,NDUFA12,LRRK2,COX6A2,PPIF,NDUFB5,VDAC3,NDUFA3 |
| Metabolic pathways | ENO1,MCAT,ADKA,Cel,INPP5E,AMPD1,CYP3A41B,MTMR8,FAM213B,NDUFS8B |
Protein Function
ATP5B has several biochemical functions, for example, ATP binding,contributes_to ATPase activity,MHC class I protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ATP5B itself. We selected most functions ATP5B had, and list some proteins which have the same functions with ATP5B. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| transporter activity | SLC22A17,SLC22A23,PTGDSB,XPO1,FABP7,SLC12A2,AP1B1,SLC4A8,SLC5A12,SEC22A |
| ATP binding | DNAH14,QARS,FBXO18,JAK3,ZRANB3,CCT2,STK35L,DHX58,UBE2L3B,PFKP |
| transmembrane transporter activity | ATP5L,SLC22A23,ATP5F1,SLC17A9,ATP5A1,SLC2A3A,SLC22A17,SLC22A7B.1,ATP5O,ATP5E |
| proton-transporting ATP synthase activity, rotational mechanism | ATP5A1,ATP6AP1,ATP5O,ATP6AP1B,ATP5E,ATP6V0C,ATP5C1 |
| MHC class I protein binding | LILRB1,TAPBP,ATP5A1,CD8B,PILRB,DERL1,TUBB,PILRB2,TAP1,Pilrb1 |
| proton-transporting ATPase activity, rotational mechanism | ATP6V0CA,TCIRG1,ATP6V0E2,ATP6V1E1B,ATP6V1H,ATP5D,ATP5E,ATP6V1B2,ATP6V0A2,ATP6V0A4 |
| protein binding | PSMB3,ZNF187,PRMT6,SMC3,NDE1,CD200R1,CHD,LGALSL,SEC16B,TMEM185A |
| contributes_to ATPase activity | SFRP5,ATP5J2,ATP5L,MSH6,MSH2,ATP5O,ATP5F1,RFC3,ABCA7,ATP5H |
Interacting Protein
ATP5B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ATP5B here. Most of them are supplied by our site. Hope this information will be useful for your research of ATP5B.
YWHAZ;ESR1;vpu;ATP5F1;PPP1CC;YWHAG;SIRT3;IKBKG;RPP14;TK1;CDK4;ANXA7;HMOX2;CDKN1A;PSME3;PIN1
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