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  • Official Full Name
  • betacellulin
  • Background
  • The protein encoded by this gene is a member of the EGF family of growth factors. It is synthesized primarily as a transmembrane precursor, which is then processed to mature molecule by proteolytic events. This protein is a ligand for the EGF receptor.
  • Synonyms
  • BTC; betacellulin; probetacellulin; Betacellulin; Betacellulin precursor; BTC; BTC_HUMAN; OTTHUMP00000160600; OTTHUMP00000219057; Probetacellulin; OTTHUMP00000160600; OTTHUMP00000219057
Cat.#:BTC-21HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Betacellulin
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Cat.#:BTC-320BTag:N/A
Source (Host):E. coliSpecies:Bovine
Product nameRecombinant Bovine Betacellulin
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Cat.#:BTC-10315HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human BTC, GST-tagged
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Cat.#:BTC-26709THTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human BTC
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Cat.#:BTC-268HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human BTC, LEVLFQ tagged
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Cat.#:BTC-377HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human BTC Protein, GST-tagged
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Cat.#:BTC-395HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human BTC, Fc tagged
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Cat.#:BTC-569HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human BTC, His tagged
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Cat.#:Btc-425MTag:FC/His
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse Btc, Fc-His tagged
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Cat.#:Btc-566MTag:
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Btc
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Cat.#:Btc-762MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Btc protein, His-tagged
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Cat.#:BTC-58CTag:His
Source (Host):HEK293Species:Cynomolgus Monkey
Product nameRecombinant Cynomolgus BTC, Fc tagged
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Cat.#:BTC-1240CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken BTC
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Cat.#:BTC-3912ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish BTC
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Cat.#:BTC-869HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Betacellulin, His-tagged
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Cat.#:BTC-933HCLTag:
Source (Host):HEK293Species:Human
Product nameRecombinant Human BTC cell lysate
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Cat.#:BTC-2505MCLTag:
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse BTC cell lysate
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Cat.#:BTC-1049CCLTag:
Source (Host):HEK293Species:Cynomolgus Monkey
Product nameRecombinant Cynomolgus BTC cell lysate
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Involved Pathway

BTC involved in several pathways and played different roles in them. We selected most pathways BTC participated on our site, such as ErbB signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with BTC were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
ErbB signaling pathway
ELK1; PIK3CG; PLCG2; SOS1; PIK3R2; SHC4; PIK3R3B; PTK2AA; MAPK8B; MAPK10

Protein Function

BTC has several biochemical functions, for example, epidermal growth factor receptor binding, growth factor activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by BTC itself. We selected most functions BTC had, and list some proteins which have the same functions with BTC. You can find most of the proteins on our site.
Function
Related Protein
Function epidermal growth factor receptor binding
Related Protein EPGN; SHC1; SNX1; FAM83B; HBEGF; YES1; ARF4; AGR2; ERBB4; FER
Function growth factor activity
Related Protein OSM; BMP2B; CTGF; CXCL1; Il2; FGF3; ENDOU; BMP8A; FGF6; TGFB1
Function protein binding
Related Protein APLP2; SILV; ZKSCAN3; BID; NUPL1; CD24; NUP62L; MUC7; KRTAP4-11; IFIT1

Interacting Protein

BTC has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BTC here. Most of them are supplied by our site. Hope this information will be useful for your research of BTC.
S100A4; KRT31; GMPPA; ERBB2

BTC Related Articles

Gezginci-Oktayoglu, S; Karatug, A; et al. Nerve Growth Factor Neutralization Suppresses beta-Cell Proliferation Through Activin A and Betacellulin. PANCREAS 44:243-249(2015).
Celebi, B; Kilic, S; et al. Development of a Novel Francisella tularensis Antigen Stained with Tetrazolium-blue for Tularemia Microagglutination Test. MIKROBIYOLOJI BULTENI 47:514-522(2013).