CCL1

  • Official Full Name

    chemokine (C-C motif) ligand 1

  • Overview

    Chemokine (C-X-C motif) ligand 1 (CXCL1) is a small cytokine belonging to the CXC chemokine family that was previously called GRO1 oncogene, GROα, KC, Neutrophil-activating protein 3 (NAP-3) and melanoma growth stimulating activity, alpha (MSGA-α). In humans, this protein is encoded by the CXCL1 gene.
  • Synonyms

    CCL1; chemokine (C-C motif) ligand 1; C-C motif chemokine 1; P500; TCA3; CCR8 ligand; SIS-epsilon; T-cell activation protein 3; small inducible cytokine A1; small-inducible cytokine A1; I-309; Scya1; Tca-3; BF534335; Ccl1;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Hamster
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • CHO
  • E.coli
  • HEK293
  • Human Cell
  • Human Cells
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • Biotin
  • DYKDDDDK
  • Fc
  • GST
  • hFc
  • His
  • Avi
  • His (Fc)
  • His|GST
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CCL1-29H Recombinant Human Chemokine (C-C Motif) Ligand 1 E.coli N/A
Human CCL1-19H Recombinant Human CCL1, hFc-tagged HEK293 hFc
Human CCL1-1532H Recombinant Human CCL1 protein, His & GST-tagged E.coli His/GST
Human CCL1-605H Recombinant Human CCL1 protein E.coli N/A
Human CCL1-0604H Recombinant Human CCL1 Protein, GST-Tagged Wheat Germ GST
Human CCL1-168H Recombinant Human CCL1, His-tagged E.coli His
Human CCL1-3060HCL Recombinant Human CCL1 cell lysate Human Cell N/A
Human CCL1-30H Recombinant Human CCL1(Lys24-Lys96) Protein, None-tagged E.coli N/A
Human CCL1-214H Recombinant Human CCL1 Protein, DYKDDDDK-tagged Human Cells DYKDDDDK
Human CCL1-69H Recombinant Human CCL1 Protein E.coli
Human CCL1-77H Recombinant Human CCL1 Protein, Biotin-tagged E.coli Biotin
Human CCL1-266C Active Recombinant Human CCL1 Protein (73 aa) CHO
Human CCL1-2918HF Recombinant Full Length Human CCL1 Protein, GST-tagged In Vitro Cell Free System GST
Human CCL1-0883H Recombinant Human CCL1 Protein (Lys24-Lys96), N-GST tagged E.coli N-GST
Human CCL1-383C Active Recombinant Human CCL1 Protein (74 aa) E.coli
Human CCL1-1856H Active Recombinant Human CCL1 protein, His & Avi-tagged, Biotinylated HEK293 His & Avi
Human CCL1-111C Active Recombinant Human CCL1 Protein (74 aa) E.coli
Mouse Ccl1-621M Recombinant Mouse Ccl1, Fc tagged Human Cell Fc
Mouse Ccl1-126M Recombinant Mouse Chemokine (C-C Motif) Ligand 1 Mammalian cells N/A
Mouse CCL1-1690MCL Recombinant Mouse CCL1 cell lysate Human Cell N/A
Mouse Ccl1-10525M Recombinant Mouse Ccl1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Ccl1-639M Recombinant Mouse Ccl1 Protein, His-tagged E.coli N-His
Mouse Ccl1-2027M Active Recombinant Mouse Ccl1 Protein HEK293
Mouse Ccl1-10525M-B Recombinant Mouse Ccl1 Protein Pre-coupled Magnetic Beads HEK293
Rat Ccl1-640R Recombinant Rat Ccl1 Protein, His-tagged E.coli N-His
Hamster Ccl1-638H Recombinant Hamster Ccl1 Protein, His&GST-tagged E.coli N-His&GST
Rhesus Macaque CCL1-678R Recombinant Rhesus monkey CCL1 Protein, His-tagged Mammalian Cell His
Rhesus Macaque CCL1-506R-B Recombinant Rhesus Macaque CCL1 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque CCL1-506R Recombinant Rhesus Macaque CCL1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Chicken CCL1-6340C Recombinant Chicken CCL1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • CCL1 Related Articles
  • CCL1 Related Gene Family
  • CCL1 Related Research Area

CCL1 involved in several pathways and played different roles in them. We selected most pathways CCL1 participated on our site, such as Cytokine-cytokine receptor interaction, Chemokine signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with CCL1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Cytokine-cytokine receptor interactionIL17RA;CRLF2;CCL23;CCL5;CD40;IFNL3;IL10;CXCR4A;CCL6
Chemokine signaling pathwaySRC;CCL2;CXCL12;CCL3;STAT2;GNG11;PTK2;NFKB1;PIK3R3

CCL1 has several biochemical functions, for example, CCR chemokine receptor binding, chemokine activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CCL1 itself. We selected most functions CCL1 had, and list some proteins which have the same functions with CCL1. You can find most of the proteins on our site.

Function Related Protein
CCR chemokine receptor bindingCCL16;CCL11;CCL3L3;CCL15;CCL44;CCL38A.4;CCL25B;CCL35.1;XCL1
chemokine activityCcl21c;CCL13;CCL20A.3;CCL35.2;CXCL12;CCL34B.1;Cxcl15;C5;CXCL8B.3

CCL1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CCL1 here. Most of them are supplied by our site. Hope this information will be useful for your research of CCL1.

Metcalf, TU; Baxter, VK; et al. Recruitment and Retention of B Cells in the Central Nervous System in Response to Alphavirus Encephalomyelitis. JOURNAL OF VIROLOGY 87:2420-2429(2013).
Birkhauser, FD; Koya, RC; et al. Dendritic Cell-Based Immunotherapy in Prevention and Treatment of Renal Cell Carcinoma: Efficacy, Safety, and Activity of Ad-GM.CAIX in Immunocompetent Mouse Models. JOURNAL OF IMMUNOTHERAPY 36:102-111(2013).
  • Q&As
  • Reviews

Q&As (5)

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How does CCL1 contribute to the pathogenesis of inflammatory conditions? 04/30/2021

CCL1 promotes the recruitment of immune cells to inflamed tissues, exacerbating inflammation and contributing to the pathogenesis of various inflammatory conditions.

Are there any ongoing clinical trials targeting CCL1 for therapeutic intervention? 06/26/2020

Several clinical trials are exploring the therapeutic potential of targeting CCL1 in autoimmune diseases and inflammatory disorders to modulate immune responses.

How does CCL1 interact with other immune modulators, and what implications does this have for drug development? 03/24/2020

CCL1 interacts with various immune modulators, and understanding these interactions is crucial for developing targeted therapies that can modulate the immune response more effectively.

In what ways does CCL1 participate in the regulation of immune responses? 05/25/2018

CCL1 regulates immune responses by influencing the migration and activation of specific immune cells, modulating the overall immune system's activity.

How does CCL1 influence the migration of specific immune cell types, and how is this mechanism exploited in clinical applications? 05/16/2016

CCL1 selectively influences the migration of specific immune cell types, and understanding this mechanism is essential for developing therapies that target specific immune responses in various diseases.

Customer Reviews (3)

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Reviews
11/14/2022

    Its exceptional purity and integrity ensure clear and reliable bands, enabling accurate detection and quantification of target proteins.

    12/03/2019

      Its stability and structural integrity make it an ideal candidate for studying protein structures at high resolution.

      11/11/2019

        I am delighted to highly recommend the aroE Protein for researchers seeking excellent performance in Western blotting (WB) experiments and protein electron microscopy structure analysis

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