Recombinant Hamster Ccl1 Protein, His&GST-tagged

Cat.No. : Ccl1-638H
Product Overview : Recombinant Hamster Ccl1 Protein (Lys24-Cys91) with His&GST tag was expressed in E. coli.
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Description : This antimicrobial gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, is secreted by activated T cells and displays chemotactic activity for monocytes but not for neutrophils. It binds to the chemokine (C-C motif) receptor 8.
Source : E. coli
Species : Hamster
Tag : N-His&GST
Form : Freeze-dried powder
Molecular Mass : Predicted Molecular Mass: 37.8 kDa; Accurate Molecular Mass: \
Protein length : Lys24-Cys91
Purity : > 90%
Applications : Positive Control; Immunogen; SDS-PAGE; WB.
Stability : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
Storage Buffer : 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
Reconstitution : Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
SDS-PAGE:
Gene Name : Ccl1 C-C motif chemokine ligand 1 [ Cricetulus griseus (Chinese hamster) ]
Official Symbol : Ccl1
Synonyms : Ccl1; C-C motif chemokine ligand 1; C-C motif chemokine 1; chemokine (C-C motif) ligand 1
Gene ID : 103159565
mRNA Refseq : XM_007644150
Protein Refseq : XP_007642340

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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How does CCL1 contribute to the pathogenesis of inflammatory conditions? 04/30/2021

CCL1 promotes the recruitment of immune cells to inflamed tissues, exacerbating inflammation and contributing to the pathogenesis of various inflammatory conditions.

Are there any ongoing clinical trials targeting CCL1 for therapeutic intervention? 06/26/2020

Several clinical trials are exploring the therapeutic potential of targeting CCL1 in autoimmune diseases and inflammatory disorders to modulate immune responses.

How does CCL1 interact with other immune modulators, and what implications does this have for drug development? 03/24/2020

CCL1 interacts with various immune modulators, and understanding these interactions is crucial for developing targeted therapies that can modulate the immune response more effectively.

In what ways does CCL1 participate in the regulation of immune responses? 05/25/2018

CCL1 regulates immune responses by influencing the migration and activation of specific immune cells, modulating the overall immune system's activity.

How does CCL1 influence the migration of specific immune cell types, and how is this mechanism exploited in clinical applications? 05/16/2016

CCL1 selectively influences the migration of specific immune cell types, and understanding this mechanism is essential for developing therapies that target specific immune responses in various diseases.

Customer Reviews (3)

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Reviews
11/14/2022

    Its exceptional purity and integrity ensure clear and reliable bands, enabling accurate detection and quantification of target proteins.

    12/03/2019

      Its stability and structural integrity make it an ideal candidate for studying protein structures at high resolution.

      11/11/2019

        I am delighted to highly recommend the aroE Protein for researchers seeking excellent performance in Western blotting (WB) experiments and protein electron microscopy structure analysis

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