Active Recombinant Mouse Ccl1 Protein

• Cat.No.: Ccl1-2027M
• Product Overview: Purified recombinant protein of Mouse chemokine (C-C motif) ligand 1 (Ccl1) without tag was expressed in HEK293.

Specification

• Description: Cytokine that is chemotactic for neutrophils.
• Source: HEK293
• Species: Mouse
• Bio-activity: Bioactivity was measured by its property to chemoattract mouse BW.5147.G.1.4OUAR.1 cells in a dose dependent manner.
• Molecular Mass: 7.7 kDa
• Protein length: Lys24-Cys92
• Endotoxin: Less than 0.01 ng/μg protein as determined by the LAL method
• Purity: > 98%, as determined by Coomassie stained SDS-PAGE.
• Stability: Unopened vial can be stored between 2 and 8 centigrade for up to 2 weeks, at -20 centigrade for up to 6 months, or at -70 centigrade or below until the expiration date. Aliquots can be stored between 2 and 8 centigrade for up to one week and stored at -20 centigrade or colder for up to 3 months. Avoid repeated freeze/thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: Protein formulated and vialed at >50 μg/mL in specified buffer
• Storage Buffer: 1 x PBS

Gene Information

• Gene Name: Ccl1 chemokine (C-C motif) ligand 1 [ Mus musculus (house mouse) ]
• Official Symbol: Ccl1
• Synonyms: CCL1; chemokine (C-C motif) ligand 1; C-C motif chemokine 1; P500; TCA3; CCR8 ligand; SIS-epsilon; T-cell activation protein 3; small inducible cytokine A1; small-inducible cytokine A1; I-309; Scya1; Tca-3; BF534335
• Gene ID: 20290
• mRNA Refseq: NM_011329
• Protein Refseq: NP_035459
• UniProt ID: P10146

Reviews

11/14/2022

Its exceptional purity and integrity ensure clear and reliable bands, enabling accurate detection and quantification of target proteins.

12/03/2019

Its stability and structural integrity make it an ideal candidate for studying protein structures at high resolution.

11/11/2019

I am delighted to highly recommend the aroE Protein for researchers seeking excellent performance in Western blotting (WB) experiments and protein electron microscopy structure analysis

Q&As

How does CCL1 contribute to the pathogenesis of inflammatory conditions?

CCL1 promotes the recruitment of immune cells to inflamed tissues, exacerbating inflammation and contributing to the pathogenesis of various inflammatory conditions.

Are there any ongoing clinical trials targeting CCL1 for therapeutic intervention?

Several clinical trials are exploring the therapeutic potential of targeting CCL1 in autoimmune diseases and inflammatory disorders to modulate immune responses.

How does CCL1 interact with other immune modulators, and what implications does this have for drug development?

CCL1 interacts with various immune modulators, and understanding these interactions is crucial for developing targeted therapies that can modulate the immune response more effectively.

In what ways does CCL1 participate in the regulation of immune responses?

CCL1 regulates immune responses by influencing the migration and activation of specific immune cells, modulating the overall immune system's activity.

How does CCL1 influence the migration of specific immune cell types, and how is this mechanism exploited in clinical applications?

CCL1 selectively influences the migration of specific immune cell types, and understanding this mechanism is essential for developing therapies that target specific immune responses in various diseases.