Recombinant Human CCL1, His-tagged CCL1-168H

Recombinant Human CCL1, His-tagged


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Recombinant Human CCL1, His-tagged

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Cat.No. : CCL1-168H Optional Service: Optional requirements on this protein
Product Overview : Recombinant human CCL1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.
Description : CCL1 (chemokine C-C motif ligand 1) is a small glycoprotein secreted by activated T cells that belongs to a family inflammatory cytokines known as chemokines. CCL1 attracts monocytes, NK cells, and immature B cells and dendritic cells by interacting with a cell surface chemokine receptor called CCR8. Unlike the other members of the C-C family, CCL1 does not induce chemotaxis in natural killer (NK) cells.
Source : E.coli.
Form : Liquid. In 20mM Tris-HCl buffer (pH 7.5) containing 2mM DTT, 10% glycerol, 50mM NaCl.
Molecular Weight : 10.8 kDa (94aa) confirmed by MALDI-TOF.
Purity : > 85% by SDS - PAGE.
Concentration : 0.5 mg/ml (determined by Bradford assay).
Endotoxin Level : < 1.0 EU per 1 μg of protein (determined by LAL method).
Storage : Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Pathways : Cytokine-cytokine receptor interaction
Gene Name : CCL1 chemokine (C-C motif) ligand 1
Synonyms : P500; SISe; TCA3; I-309; SCYA1; small inducible cytokine A1; inflammatory cytokine I-309; T lymphocyte-secreted protein I-309; small inducible cytokine A1 (I-309, homologous to mouse Tca-3); chemokine (C-C motif) ligand 1; CCL1
Gene ID : 6346
mRNA Refseq : NM_002981
Protein Refseq : NP_002972
MIM : 182281
UniProt ID : P22362
Chromosome Location : 17q12
Function : chemokine activity
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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