Recombinant Human CCL1 protein, His & GST-tagged

• Cat.No.: CCL1-1532H
• Product Overview: Recombinant Human CCL1 aa. (Lys24~Lys96 (Accession # P22362)) fused with N-terminal His & GST tag was produced in E. coli cells.

Specification

• Species: Human
• Source: E.coli
• Tag: GST&His
• Protein Length: Lys24~Lys96
• Description: This antimicrobial gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, is secreted by activated T cells and displays chemotactic activity for monocytes but not for neutrophils. It binds to the chemokine (C-C motif) receptor 8.
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 40.9kDa.
• Endotoxin: <1.0EU per 1µg (determined by the LAL method).
• Purity: >95%
• Characteristic: The isoelectric point is 8.7.
• Applications: SDS-PAGE; WB; ELISA; IP.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.

Gene Information

• Gene Name: CCL1 C-C motif chemokine ligand 1 [ Homo sapiens (human) ]
• Official Symbol: CCL1
• Synonyms: P500; SISe; TCA3; I-309; SCYA1; T lymphocyte-secreted protein I-309; chemokine (C-C motif) ligand 1; inflammatory cytokine I-309; small inducible cytokine A1 (I-309, homologous to mouse Tca-3); C-C motif chemokine 1
• Gene ID: 6346
• mRNA Refseq: NM_002981.2
• Protein Refseq: NP_002972.1
• UniProt ID: P22362