Recombinant Mouse Chemokine (C-C Motif) Ligand 1

• Cat.No.: Ccl1-126M

Specification

• Cat. No.: Ccl1-126M
• Description: Chemokine (C-C motif) ligand 1 (CCL1) is a small glycoprotein secreted by activated T cells that belongs to a family inflammatory cytokines known as chemokines. CCL1 attracts monocytes, NK cells, and immature B cells and dendritic cells by interacting with a cell surface chemokine receptor called CCR8. CCL1 may play a role in lymphocyte recruitment in bronchial asthma.
• Source: Mammalian cells
• State Of Matter: Lyophilized.
• Purity: >95% by SDS Page and analyzed by silver stain.
• Endotoxin: <1.0 EU/µg as determined by the LAL method.
• Molecular Weight: The predicted molecular weight of Recombinant Mouse CCL1 is Mr 7.8 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 13-16 kDa.
• Storage And Stability: This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
• Tag: Non

Gene Information

• Gene Name: Ccl1 chemokine (C-C motif) ligand 1 [ Mus musculus ]
• Synonyms: chemokine (C-C motif) ligand 1; I-309; Scya1; Tca-3; BF534335; Ccl1; CCR8 ligand; OTTMUSP00000000867; small inducible cytokine A1; CCR8 ligand
• Gene ID: 20290
• mRNA Refseq: NM_011329
• Protein Refseq: NP_035459
• UniProt ID: P10146
• Chromosome Location: 11 47.32 cM
• Pathway: Chemokine signaling pathway; Cytokine-cytokine receptor interaction
• Function: chemokine activity; cytokine activity; protein binding

Reviews

11/14/2022

Its exceptional purity and integrity ensure clear and reliable bands, enabling accurate detection and quantification of target proteins.

12/03/2019

Its stability and structural integrity make it an ideal candidate for studying protein structures at high resolution.

11/11/2019

I am delighted to highly recommend the aroE Protein for researchers seeking excellent performance in Western blotting (WB) experiments and protein electron microscopy structure analysis

Q&As

How does CCL1 contribute to the pathogenesis of inflammatory conditions?

CCL1 promotes the recruitment of immune cells to inflamed tissues, exacerbating inflammation and contributing to the pathogenesis of various inflammatory conditions.

Are there any ongoing clinical trials targeting CCL1 for therapeutic intervention?

Several clinical trials are exploring the therapeutic potential of targeting CCL1 in autoimmune diseases and inflammatory disorders to modulate immune responses.

How does CCL1 interact with other immune modulators, and what implications does this have for drug development?

CCL1 interacts with various immune modulators, and understanding these interactions is crucial for developing targeted therapies that can modulate the immune response more effectively.

In what ways does CCL1 participate in the regulation of immune responses?

CCL1 regulates immune responses by influencing the migration and activation of specific immune cells, modulating the overall immune system's activity.

How does CCL1 influence the migration of specific immune cell types, and how is this mechanism exploited in clinical applications?

CCL1 selectively influences the migration of specific immune cell types, and understanding this mechanism is essential for developing therapies that target specific immune responses in various diseases.