CD209 Protein

September 27-30, 2022

Boston Convention and Exhibition Center

Booth #336

Learn More

  • 00


  • 00


  • 00


  • 00



Home / Products / CD209


Official Full Name CD209 molecule
Background This gene encodes a transmembrane receptor and is often referred to as DC-SIGN because of its expression on the surface of dendritic cells and macrophages. The encoded protein is involved in the innate immune system and recognizes numerous evolutionarily divergent pathogens ranging from parasites to viruses with a large impact on public health. The protein is organized into three distinct domains: an N-terminal transmembrane domain, a tandem-repeat neck domain and C-type lectin carbohydrate recognition domain. The extracellular region consisting of the C-type lectin and neck domains has a dual function as a pathogen recognition receptor and a cell adhesion receptor by binding carbohydrate ligands on the surface of microbes and endogenous cells. The neck region is important for homo-oligomerization which allows the receptor to bind multivalent ligands with high avidity. Variations in the number of 23 amino acid repeats in the neck domain of this protein are rare but have a significant impact on ligand binding ability. This gene is closely related in terms of both sequence and function to a neighboring gene (GeneID 10332; often referred to as L-SIGN). DC-SIGN and L-SIGN differ in their ligand-binding properties and distribution. Alternative splicing results in multiple variants.[provided by RefSeq, Feb 2009]
Synonyms CD209; CD209 molecule; CDSIGN; CLEC4L; DC-SIGN; DC-SIGN1; CD209 antigen; HIV gpl20-binding protein; C-type lectin domain family 4 member L; C-type lectin domain family 4, member L; dendritic cell-specific ICAM-3-grabbing non-integrin 1; dendritic cell-specific intracellular adhesion molecules (ICAM)-3 grabbing non-integrin;
    • Species :
    • Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops)
    • Human
    • Rhesus
    • Zebrafish
    • Source :
    • CHO
    • E.coli
    • E.coli expression system
    • HEK293
    • Human Cell
    • Mammalian Cell
    • Mammalian cells
    • Wheat Germ
    • Tag :
    • Fc
    • GST
    • His
    • T7
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CD209-636H Recombinant Human CD209 protein, Fc-tagged Mammalian cells Fc
    Human CD209-0747H Recombinant Human CD209 Protein Wheat Germ N/A
    Human CD209-0748H Recombinant Human CD209 Protein, GST-Tagged Wheat Germ GST
    Human CD209-633H Recombinant Human CD209, Fc tagged Human Cell Fc
    Human CD209-634H Recombinant Human CD209 protein, Fc-tagged HEK293 Fc
    Human CD209-635H Recombinant Human CD209 protein CHO N/A
    Human CD209-7173H Recombinant Human CD209 protein, His & T7-tagged E.coli His/T7
    Rhesus CD209-727R Recombinant Rhesus CD209 protein, His-tagged HEK293 His
    Rhesus CD209-728R Recombinant Rhesus CD209 protein, Fc-tagged HEK293 Fc
    Zebrafish CD209-7858Z Recombinant Zebrafish CD209 Mammalian Cell His
    Human CD209-2986HCL Recombinant Human CD209 cell lysate Human Cell N/A
    Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops) RFL7980CF Recombinant Full Length Chlorocebus Aethiops Cd209 Antigen(Cd209) Protein, His-Tagged E.coli expression system His
    Human CD209-643H Recombinant Human CD209 protein, His-tagged HEK293 His
    Rhesus CD209-726R Recombinant Rhesus CD209 protein (Lys62-Glu381), His-tagged HEK293 His

    CD209 involved in several pathways and played different roles in them. We selected most pathways CD209 participated on our site, such as Phagosome, Tuberculosis, Measles, which may be useful for your reference. Also, other proteins which involved in the same pathway with CD209 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Tuberculosis CD209A; CD14; TNF; PMAP-36; LBP; ATP6V0D1; TLR4; HSPA9; BID; MRC1
    Measles IFIH1; IFNA2; PIK3R1; IFNA21; HSPA1L; TP53; IL2RB; FAS; IFNGR2; MSN

    CD209 has several biochemical functions, for example, carbohydrate binding, mannose binding, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CD209 itself. We selected most functions CD209 had, and list some proteins which have the same functions with CD209. You can find most of the proteins on our site.

    Function Related Protein
    carbohydrate binding ACAN; MAN2A2; CLEC4E; PRG2; LGALS2; SFTPD; NOMO1; REG3A; PRPS1; CLEC11A
    mannose binding LMAN2L; CD207; DPM1; LMAN2; CLN5; LMAN1; CD209B; CLEC4M; CD209A; MANBA
    metal ion binding CUBN; ZFP11; NEURL1AA; SP8B; USP2; EXTL3; TKTL1; ZIM3; ZFP865; FOLH1
    peptide antigen binding HLA-DQA1; HLA-DRB4; TAPBP; HLA-DPB1; HLA-DQB1; MHC1UDA; HLA-E; H2-AB1; MHC1ZFA; HLA-DPA1
    protein binding CELSR1; TMEM14C; ERGIC2; ADORA2A; PTGES3; Cd24a; CHRNA5; DDX47; CSF2RA; RAB7
    virion binding APCS; PVRL1; HIPK2; HSP90B1; CD209; CLEC4M; PTX3; TSG101; PPIA
    virus receptor activity CD86; ITGA2; LAMP1; IDE; CD4; CLEC4M; HTR2A; HYAL2; CD209A; PVRL2

    CD209 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CD209 here. Most of them are supplied by our site. Hope this information will be useful for your research of CD209.

    VAC14; q03463-pro_0000278734

    Park, KT; Burnett, S; et al. Development and characterization of a monoclonal antibody specific for bovine CD209. VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY 163:216-220(2015).
    Paul, M; Reljic, R; et al. Characterization of a plant-produced recombinant human secretory IgA with broad neutralizing activity against HIV. MABS 6:1585-1597(2014).

    Related Services & Products

    Apply For A Coupon

    $50 OFF Your First Purchase

    Apply For a Coupon

    Enter your email here to subscribe.

    creative biomart inc.

    Easy access to products and services you need from our library via powerful searching tools.

    Follow Us

    Copyright © 2022 Creative BioMart. All Rights Reserved. Terms and Conditions | Privacy Policy