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Official Full Name clusterin
Background The protein encoded by this gene is a secreted chaperone that can under some stress conditions also be found in the cell cytosol. It has been suggested to be involved in several basic biological events such as cell death, tumor progression, and neurodegenerative disorders. Alternate splicing results in both coding and non-coding variants.[provided by RefSeq, May 2011]
Synonyms CLU; clusterin; CLI; AAG4; APOJ; CLU1; CLU2; KUB1; SGP2; APO-J; SGP-2; SP-40; TRPM2; TRPM-2; NA1/NA2; apolipoprotein J; ku70-binding protein 1; sulfated glycoprotein 2; aging-associated protein 4; complement lysis inhibitor; complement cytolysis inhibitor; complement-associated protein SP-40,40; testosterone-repressed prostate message 2;
    • Species :
    • Canine
    • Cattle
    • Chicken
    • Dog
    • Human
    • Mouse
    • Pig
    • Rabbit
    • Rat
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Human Cell
    • Human Plasma
    • Mammalian Cell
    • Mammalian cells
    • Mouse
    • Plasma
    • Wheat Germ
    • Tag :
    • Fc
    • His
    • Flag
    • GST
    • S
    • T7
    • MYC/DDK
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CAB11516MH Mouse Anti-Human Clusterin Monoclonal Antibody Mouse N/A
    Human CLU-106H Recombinant Human CLU, Flag-tagged HEK293 Flag
    Human CLU-10H Recombinant Human CLU, His-tagged HEK293 His
    Human CLU-11356H Recombinant Human CLU, GST-tagged E.coli GST
    Human CLU-11H Recombinant Human CLU protein, His-tagged HEK293 His
    Human CLU-1526H Recombinant Human CLU Protein, GST-tagged Wheat Germ GST
    Human CLU-19H Native Human Clusterin Protein Human plasma N/A
    Human CLU-2198HCL Recombinant Human CLU cell lysate Human Cell N/A
    Human CLU-223H Recombinant Human CLU, C13&N15-labeled HEK293 N/A
    Human CLU-26745TH Recombinant Human CLU protein, FLAG-tagged HEK293 FLAG
    Human CLU-26748TH Recombinant Human CLU, His-tagged His
    Human CLU-2751H Recombinant Human CLU Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human CLU-3277H Recombinant Human CLU Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human CLU-3661H Human Clusterin N/A
    Human CLU-3893H Recombinant Human CLU, His tagged Human Cell His
    Human CLU-4122H Native Human Clusterin Protein Human Plasma N/A
    Human CLU-4585H Recombinant Human CLU Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human CLU-67H Native Human Clusterin Plasma N/A
    Human CLU-722H Recombinant Human CLU, His-tagged Mammalian cells His
    Human CLU-841H Recombinant Human CLU Protein HEK293 N/A
    Human CLU-842H Recombinant Human CLU Protein, Fc/His-tagged HEK293 Fc/His
    Mouse Clu-039M Recombinant Mouse Clu Protein, His-tagged HEK293 His
    Mouse Clu-040M Recombinant Mouse Clu Protein, MYC/DDK-tagged HEK293T MYC/DDK
    Mouse Clu-1317M Recombinant Mouse Clusterin, Flag-tagged HEK293 Flag
    Mouse Clu-1867M Recombinant Mouse Clusterin HEK293 N/A
    Mouse CLU-2195MCL Recombinant Mouse CLU cell lysate Human Cell N/A
    Mouse Clu-3302M Recombinant Mouse Clu, His tagged Human Cell His
    Mouse Clu-5774M Recombinant Mouse Clu protein, His-tagged E.coli His
    Rat Clu-108R Recombinant Rattus Clusterin, His-tagged, T7-tagged E.coli His
    Rat CLU-1472R Recombinant Rat CLU Protein Mammalian Cell His
    Rat Clu-2679R Recombinant Rat Clusterin, T7-His E.coli T7/His
    Rat Clu-3664R Recombinant Rat Clu, His-tagged E.coli His
    Rhesus Macaque CLU-921R Recombinant Rhesus monkey CLU Protein, His-tagged Mammalian Cell His
    Canine CLU-1318C Recombinant Canine Clusterin, His-tagged E.coli His
    Canine CLU-1319C Recombinant Canine Clusterin, Flag-tagged HEK293 Flag
    Dog CLU-5773D Recombinant Dog CLU protein, His & S-tagged E.coli His/S
    Rabbit CLU-5777R Recombinant Rabbit CLU protein, His-tagged E.coli His
    Chicken CLU-6462C Recombinant Chicken CLU Mammalian Cell His
    Zebrafish CLU-11058Z Recombinant Zebrafish CLU Mammalian Cell His
    Cattle CLU-5772C Recombinant Cattle CLU protein, His & T7-tagged E.coli His/T7
    Pig CLU-5776P Recombinant Pig CLU protein, His-tagged E.coli His

    Clu involved in several pathways and played different roles in them. We selected most pathways Clu participated on our site, such as Hemostasis, Platelet activation, signaling and aggregation, Platelet degranulation, which may be useful for your reference. Also, other proteins which involved in the same pathway with Clu were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Hemostasis GATA5; CFHL4; SLC8A2A; CAP1; ABHD12; IGF2B; GNA13; AKAP10; CENPE; HMG20B
    Platelet activation, signaling and aggregation ABHD6B; STXBP3A; CALU; G6b; RHOGA; C6orf25; GNA13B; F13A1A.1; SRGN; TFA
    Platelet degranulation AASS; PLEK; CLU; SPARC; F13A1A.1; HRG; TFA; F13A1B; MMRN2A; BRPF3
    Response to elevated platelet cytosolic Ca2+ STXBP3A; F13A1A.1; CALU; SPARC; CLU; MMRN1; MMRN2A; F13A1B; CAP1; BRPF3
    Validated targets of C-MYC transcriptional repression MXD4; CLU; SFXN3; CSDE1; S100A7; TMEM126A; ZFP36L1; LGALS1; DNTT; GFI1

    Clu has several biochemical functions, for example, NOT ATPase activity, chaperone binding, misfolded protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Clu itself. We selected most functions Clu had, and list some proteins which have the same functions with Clu. You can find most of the proteins on our site.

    Function Related Protein
    NOT ATPase activity KIF26A; CLU; RUVBL1; MYO18A
    chaperone binding CDC37L1; CTSC; UBL4; SYVN1; DNLZ; BAG3; GET4; DNAJB2; TSC1; PARK2
    misfolded protein binding STUB1; BAG6; TOR1A; CLU; F12; SDF2L1; HSPA5; HDAC6; HSPD1; EDEM1
    protein binding NUP85; ARNT; FCN3; TOMM70A; MRPS31; GOPC; IQCE; SOX10; NCOR1; NR1I2
    ubiquitin protein ligase binding CCDC50; IKBKE; BLZF1; FHIT; RB1; USP25; DERL1; UBE2B; LC3; PTPN22

    Clu has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Clu here. Most of them are supplied by our site. Hope this information will be useful for your research of Clu.

    PDIA3; ADCYAP1; FOS; PPARG; Stag2; NR3C1; ZNF24; NR4A1; MDM2; BCL2L1; KLF11; POLR1C; CYP2E1

    Mourra, N; Scriva, A; et al. Clusterin expression in gastrointestinal neuroendocrine tumours is highly correlated with location and is helpful in determining the origin of liver metastases. HISTOPATHOLOGY 65:642-650(2014).
    Shabayek, MI; Sayed, OM; et al. Diagnostic Evaluation of Urinary Angiogenin (ANG) and Clusterin (CLU) as Biomarker for Bladder Cancer. PATHOLOGY & ONCOLOGY RESEARCH 20:859-866(2014).

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