Recombinant Mouse Clu Protein, MYC/DDK-tagged

• Cat.No.: Clu-040M
• Product Overview: Purified recombinant protein of full-length mouse clusterin (Clu), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: The protein encoded by this gene is a secreted chaperone that can, under some stress conditions, also be found in the cell cytosol. It has been suggested to be involved in several basic biological events such as cell death, tumor progression, and neurodegenerative disorders. The encoded preproprotein undergoes proteolytic processing to generate a disulfide-linked heterodimeric mature protein comprised of alpha and beta subunits. Mice lacking the encoded protein exhibit increased severity of autoimmune myocarditis, faster progression of the acute inflammation to myocardial scarring and decreased brain injury following neonatal hypoxic-ischemic injury.
• Molecular Mass: 51.7 kDa
• Purity: >80%, as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 ug/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Clu clusterin [ Mus musculus (house mouse) ]
• Official Symbol: Clu
• Synonyms: Clu; clusterin; Cli; ApoJ; Sgp2; SP-40; Sgp-2; Sugp-2; AI893575; D14Ucla3; clusterin; Apolipoprotein J; clustrin; complement lysis inhibitor; sulfated glycoprotein 2; testosterone repressed prostate message; testosterone repressed prostate message-2
• Gene ID: 12759
• mRNA Refseq: NM_013492
• Protein Refseq: NP_038520
• UniProt ID: Q06890