Recombinant human CLU protein (23-449aa), N-6×His-tagged

• Cat.No.: CLU-13H
• Product Overview: Recombinant human CLu protein (23-449aa), fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Specification

• Description: The protein encoded by this gene is a secreted chaperone that can under some stress conditions also be found in the cell cytosol. It has been suggested to be involved in several basic biological events such as cell death, tumor progression, and neurodegenerative disorders. Alternate splicing results in both coding and non-coding variants.
• Source: E.coli
• Species: Human
• Tag: N-6×His
• Form: Liquid
• Molecular Mass: 54.1 kDa (463aa)
• Protein Length: 23-449
• AA Sequence: MRGSHHHHHHGMASMTGGQQMGRDL YDDDDKDRWGSDQTVSDNELQEMSN QGSKYVNKEIQNAVNGVKQIKTLIE KTNEERKTLLSNLEEAKKKKEDALN ETRESETKLKELPGVCNETMMALWE ECKPCLKQTCMKFYARVCRSGSGLV GRQLEEFLNQSSPFYFWMNGDRIDS LLENDRQQTHMLDVMQDHFSRASSI IDELFQDRFFTREPQDTYHYLPFSL PHRRPHFFFPKSRIVRSLMPFSPYE PLNFHAMFQPFLEMIHEAQQAMDIH FHSPAFQHPPTEFIREGDDDRTVCR EIRHNSTGCLRMKDQCDKCREILSV DCSTNNPSQAKLRRELDESLQVAER LTRKYNELLKSYQWKMLNTSSLLEQ LNEQFNWVSRLANLTQGEDQYYLRV TTVASHTSDSDVPSGVTEVVVKLFD SDPITVTVPVEVSRKNPKFMETVAE KALQEYRKKHREE
• Purity: >85% by SDS-PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at +2 to +8 centigrade for 1 week. For long term storage, aliquot and store at -20 to -80 centigrade. Avoid repeated freezing and thawing cycles.
• Concentration: 0.5 mg/mL (determined by Bradford assay)
• Storage Buffer: 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT

Gene Information

• Gene Name: CLU clusterin [ Homo sapiens (human) ]
• Official Symbol: CLU
• Synonyms: CLU; clusterin; APOJ, CLI, clusterin (complement lysis inhibitor, SP 40,40, sulfated glycoprotein 2, testosterone repressed prostate message 2, apolipoprotein J); apolipoprotein J; complement lysis inhibitor; KUB1; SGP 2; SP 40; sulfated glycoprotein 2; testosterone repressed prostate message 2; TRPM 2; ku70-binding protein 1; aging-associated protein 4; complement cytolysis inhibitor; complement-associated protein SP-40,40; testosterone-repressed prostate message 2; CLI; AAG4; APOJ; SGP2; APO-J; SGP-2; SP-40; TRPM2; TRPM-2; NA1/NA2; MGC24903
• Gene ID: 1191
• mRNA Refseq: NM_001831
• Protein Refseq: NP_001822
• MIM: 185430
• UniProt ID: P10909